Комплексная оценка состояния здоровья первоклассников в процессе адаптации к обучению в образовательных учреждениях нового типа

The state of health, vegetative homeostasis and parameters of local immunity 104 first-graders at the age of 6—8 years in adaptation to training in educational institutions of the general type and with the raised academic load is studied. It is shown that the current of adaptable process of the first-graders trained in educational institutions of new type is interfaced to growth of a chronic pathology, infringement of a vegetative homeostasis and a condition of local immunity of mucous membranes (maintenance increase sekretori immunoglobulin A, activity decrease kaspazy-3 asaliva), testifying to decrease in nonspecific resistance of an organism of children.Изучено состояние здоровья, вегетативный гомеостаз и параметры местного иммунитета 104 первоклассников в возрасте 6—8 лет в период адаптации к обучению в образовательных учреждениях общего типа и с повышенной учебной нагрузкой. Показано, что течение адаптационного процесса первоклассников, обучающихся в образовательных учреждениях нового типа, сопряжено с ростом хронической патологии, нарушением вегетативного гомеостаза и состояния местного иммунитета слизистых оболочек (увеличение содержания секреторного иммуноглобулина A, снижение активности каспазы-3 слюны), свидетельствующими о снижении неспецифической резистентности организма детей

The risk of acute myocardial infarction development in long-term radiation exposure

Study of risk acute myocardial infarction (AMI) development in persons (80,2% males) exposed to long-term low doses ionizing radiation and chemical factors.Prospective cohort study of AMI morbidity in period 1998—2006 among the personal, exposed to long-term professional radiation and chemical factors.Risk AMI development increase in group of male personel exposed combined radiation and chemical factors. The obtained results indicate that possible summation of «traditional» AMI development risk factors and radiation factor negative influence on endothelial tissue

Complex estimation of a state of health of first-graders in the process of adaptation to training in educational institutions new type

The state of health, vegetative homeostasis and parameters of local immunity 104 first-graders at the age of 6—8 years in adaptation to training in educational institutions of the general type and with the raised academic load is studied. It is shown that the current of adaptable process of the first-graders trained in educational institutions of new type is interfaced to growth of a chronic pathology, infringement of a vegetative homeostasis and a condition of local immunity of mucous membranes (maintenance increase sekretori immunoglobulin A, activity decrease kaspazy-3 asaliva), testifying to decrease in nonspecific resistance of an organism of children

ANTIHYPERTENSIVE TREATMENT WITH COMBINED DRUG OF LOSARTAN AND HYDROCHLOROTHIAZIDE

Aim:  to evaluate efficiency and safety of the combined antihypertensive drug Lozap Plus (50 mg losartan, 12,5 mg hydrochlorothiazide) in patients with arterial hypertension (AH) of I-III grade with high and very high cardiovascular risk. Material and methods: 30 patients with AH of I-III grade (13 men and 17 women aged 51.9±1.9) were observed. Patients received Lozan Plus (Zentiva, Czech Republic) 1 time in the morning during 12 weeks. Ambulatory blood pressure monitoring (ABPM), echocardiography, biochemical blood analysis were carried out, microalbuminuria (MA) was determined, quality of life was assessed. Results: After 2 weeks of therapy decrease in office systolic blood pressure (BP) was observed, and after 4 weeks - in diastolic BP. After 12 weeks of treatment decrease in BP became more significant. Target systolic and diastolic BP was reached in 83.3% and 90% of patients respectively. Decrease in systolic BP was observed in 24 hrs. (from 141.9±1.9 to 128.6±0.8 mmHg, p<0.001), in daytime (from 146.8±2.6 to 135.8±1.0 mmHg, p<0.01) and in nighttime (from 131.5±1.9 to 118.8±1.9 mmHg, p<0.001). Diastolic BP also decreased: in 24 hrs. (from 91.7±1.8 to 78.7±1.6 mmHg, p<0.05), in daytime (from 94.3±1.3 to 85.0±1.2 mmHg, p<0.05) and in nighttime (from 83.5±2.0 to 71.2±1.7 mmHg, p<0.01). Daily variability of BP, time index of BP and morning BP rise (from 37.6±2.0 to 23.9±1.9 mmHg, p<0.001) reduced. Normalization of daily profile of BP was observed in the majority of patients after 12 weeks of Lozap Plus therapy. Treatment resulted in reduction of number of patients with myocardial hypertrophy (from 50% to 30%, p<0.01), and of patients with diastolic dysfunction of left ventricle (from 43.3% to 30%, p<0.05). Therapy with Lozap Plus during 12 weeks was followed by decrease in MA from 56.7±1.1 mg/l to 9.0±0.5 mg/l. Lozap Plus demonstrated metabolic safety by assessing carbohydrate, lipid, nitric and electrolyte blood parameters. Increase in quality of life was observed by week 12 of treatment. Conclusion: Lozap Plus is efficient antihypertensive drug providing cardio- and nephroprotection, which doesn’t cause metabolic disturbances and improves quality of life of hypertensive patients

The future of the moment before. Scenarios for Russian society, torn between political and discontinuities and social continuities

Il volume tratta di scenari che girano intorno alle discontinuit\ue0 politiche e istituzionalinel passaggio tra URSS e Federazione Russia e alle continuit\ue0 sociali. Vengono trattati quindi i processi sociali, i prerequisiti per la formazione della classe media, i problemi socio-economici nelle relazioni etniche, l'adeguata interpretazione fri grandi cambiamenti, la percezione psicologica della nuova realt\ue0, i valori umanitari, rapporto fra intellighentia e potere, movimenti socio-politici, lo sviluppo russ