Results of adolescent health risk assesment on exposure to habitat water peroral factor in conditions of a large industrial city

Results of the non-carcinogenic risk assessment on ingestion of chemical substances with drinking water showed that the risk value corresponded to the allowable level of the non-carcinogenic risk (HQ ( 1) for the major part of elements in all zones. The excess of the allowable level is observed only in oil products in the 1st zone (2.05) and the 4th zone (1.04). However, the total hazard index (HI) on combined peroral ingestion of chemical compounds and elements with drinking water in selected zones of the city of Kazan implies a low risk level for adolescents living in the 1st and the 4th zones (3.7 and 3.59) correspondingly, and is dangerous for health. According to the results of analysis carried out in all zones, the following basic critical organs and systems were identified: blood, CNS, kidneys, endocrine system, cardiovascular system, skeletal system and teeth. The total hazard indices in the 1st and the 4th zones deserve particular attention

Risk assessment of the rural population health from exposure to polluted food products

In the diet of the rural population, milk, dairy products, meat and meat products, fish, bread, and bread products make the largest contribution to the exposition of cadmium, arsenic, and mercury. The cardiovascular, hormonal, central nervous, immune, reproductive systems, blood, and kidneys are most at risk. Non-carcinogenic risk for imported food products is determined by the systems: Blood, hormonal, central nervous, and reproductive. Materials and Methods: Statistical analysis of the obtained data was implemented operating system Windows 2007 with the application of standard application program packages Excel 2007 and "Statistics v.6.0". Result and Discussion: Comparative analysis of the obtained data revealed that the Republic of Tatarstan had higher indices in the content of pollutants in the fruit and vegetable products

Efficiency of maintaining reservoir pressure in oil wells during the development of carbonate reservoirs

The paper analyzes the operation dynamics of injection and observation production wells. It assesses the impact of injection wells on produced water density. The reservoir is characterized by out-contour flooding. It was found that such a scheme is ineffective due to the weak hydrodynamic relationship of the reservoir with the aquifer, which is confirmed by the result of this analysis, and the selective (focal) water flooding used on the Kizelovsky horizon also does not have the proper effect, and there is no correlation of formation pressure with injection in observation wells. It was shown that large volumes of water injection into injection wells do not maintain formation pressure in certain areas, but in general, there is a slight positive impact on the development indicators for the target. The recommendations for optimizing the formation pressure maintenance system were proposed based on the results of the analysis

Integrated Ecological-Economic Modeling of Regions with the use of GIS Technologies

The paper shows the process of modeling the integrated map “Scheme of the ecological and economic regionalization of the territory of the Russian Federation on the basis of the mineral and raw materials base of natural adsorbents” using GIS technologies. The map is based on three main groups of indicators: natural, economic and environmental. The ecological content of the map is characterized by indicators that are potential or actual sources of pollutant release into the environment (nuclear power plants, nuclear reactors, radioactive waste storage and disposal sites, nuclear test sites, industrial enterprises, railways, operating and under construction oil pipelines, hydrocarbon fields, etc.). The economic component of the map is the reserves estimated by the indicators of study and development, the relationship to the subsoil fund and forecast resources. The natural group of indicators is represented by the mineral and raw material base of natural adsorbents (fields and objects of forecast resources) that can be used to prevent harmful emissions and for the ecological and economic rehabilitation of contaminated areas. Based on the analysis of cartographic data, the ecological and economic areas of the territorial distribution of man-caused environmental impacts and the presence of adsorption raw materials are identified. As an example, a description is given of the ecological and economic model of the regionalization of the Privolzhsky Federal District using the GIS “Mineral resource base of natural adsorbents of Russia” developed at the Federal State Unitary Enterprise TsNIIgeolnerud

The Risk of the Development of Non-Carcinogenic Effects from Exposure to Chemicals that Pollute the Atmospheric Air for the Health of Adolescents in an Urbanized Areas (Using the Example of Kazan)

© 2020 IOP Publishing Ltd. All rights reserved. Assessment of risk for adolescents due to atmospheric air pollution showed that the highest contribution to the total value of HI on inhalation route of entry was made by the suspended particulate matters PM 2.5 and the spread of values in the districts was from 15.03 % to 18.68 %. 12.02% - 20.95%; carbon (soot) - (11.54% - 18.68%) and formaldehyde (4.88% - 9.47%) ranked second. An alarming level of risk for adolescents was identified in 1 (HI = 3.04) and 2 (HI = 3.23) zones of the city. The risk of diseases of the blood ranked second in general toxic action of chemicals. The total risk of developing non-carcinogenic effects in adolescents on entry of chemicals with atmospheric air corresponded to average level. The substances contributing the main percentage share to the risk of developing non-carcinogenic effects are carbon (soot), suspended particulate matters (PM10 and PM 2.5), nitrogen dioxide, carbon oxide, and formaldehyde

Peak window correlation method for drug screening using Raman spectroscopy

© 2018 Elsevier B.V. Modern portable and hand-held Raman spectrometers that recently have become widespread in drug quality screening have good reproducibility and are able to detect small concentrations of substances in mixtures of several components or distinguish compounds similar in structure and having minimal differences in spectrum with appropriate mathematical processing methods. Among other spectrum comparison approaches, the peak search at their location is the most important task of spectral imaging of the studied samples. In this work, the Raman spectra of liquid drugs involved in the governmental non-destructive quality screening program performed by 8 mobile laboratories equipped with Raman spectrometers with uncooled detector and a 532 nm laser were compared with reference sample spectra using the peak windows correlation (PWC) algorithm developed in this work by authors. The proposed method provides accurate identification, detection of composition changes, and presence of foreign components in drugs formulations even if their contribution to the overall signal is negligible. The spectral correlation method called hit-quality index (HQI) method conventionally used for such portable spectrometers was specified as comparative method

Peak window correlation method for drug screening using Raman spectroscopy

© 2018 Elsevier B.V. Modern portable and hand-held Raman spectrometers that recently have become widespread in drug quality screening have good reproducibility and are able to detect small concentrations of substances in mixtures of several components or distinguish compounds similar in structure and having minimal differences in spectrum with appropriate mathematical processing methods. Among other spectrum comparison approaches, the peak search at their location is the most important task of spectral imaging of the studied samples. In this work, the Raman spectra of liquid drugs involved in the governmental non-destructive quality screening program performed by 8 mobile laboratories equipped with Raman spectrometers with uncooled detector and a 532 nm laser were compared with reference sample spectra using the peak windows correlation (PWC) algorithm developed in this work by authors. The proposed method provides accurate identification, detection of composition changes, and presence of foreign components in drugs formulations even if their contribution to the overall signal is negligible. The spectral correlation method called hit-quality index (HQI) method conventionally used for such portable spectrometers was specified as comparative method