Risk factors for occupational brucellosis among veterinary personnel in Turkey

WOS: 000346883000006PubMed ID: 25132061Veterinarians and veterinary technicians are at risk for occupational brucellosis. We described the risk factors of occupational brucellosis among veterinary personnel in Turkey. A multicenter retrospective survey was performed among veterinary personnel who were actively working in the field. Of 712 veterinary personnel, 84(11.8%) had occupational brucellosis. The median number of years since graduation was 7 (interquartile ranges [IQR], 4-11) years in the occupational brucellosis group, whereas this number was 9 (IQR, 4-16) years in the non-brucellosis group (p < 0.001). In multivariable analysis, working in the private sector (odds ratio [OR], 2.8; 95% confidence interval [95% CI], 1.55-5.28, p = 0.001), being male (OR, 4.5; 95% CI, 1.05-18.84, p = 0.041), number of performed deliveries (OR, 1.01; 95% CI, 1.002-1.02, p = 0.014), and injury during Brucella vaccine administration (OR, 5.4; 95% CI, 3.16-9.3, p < 0.001) were found to be risk factors for occupational brucellosis. We suggest that all veterinary personnel should be trained on brucellosis and the importance of using personal protective equipment in order to avoid this infection. (C) 2014 Elsevier B.V. All rights reserved

Mortality-associated factors of candidemia: a multi-center prospective cohort in Turkey

Candidemia may present as severe and life-threatening infections and is associated with a high mortality rate. This study aimed to evaluate the risk factors associated with 30-day mortality in patients with candidemia. A multi-center prospective observational study was conducted in seven university hospitals in six provinces in the western part of Turkey. Patient data were collected with a structured form between January 2018 and April 2019. In total, 425 episodes of candidemia were observed during the study period. Two hundred forty-one patients died within 30 days, and the 30-day crude mortality rate was 56.7%. Multivariable analysis found that SOFA score (OR: 1.28, CI: 1.154-1.420, p < 0.001), parenteral nutrition (OR: 3.9, CI: 1.752-8.810, p = 0.001), previous antibacterial treatment (OR: 9.32, CI: 1.634-53.744,p = 0.012), newly developed renal failure after candidemia (OR: 2.7, CI: 1.079-6.761, p=0.034), and newly developed thrombocytopenia after candidemia (OR: 2.6, CI: 1. 057-6.439, p =0.038) were significantly associated with 30-day mortality. Central venous catheter removal was the only factor protective against mortality (OR: 0.34, CI:0.147-0.768, p = 0.010) in multivariable analysis. Candidemia mortality is high in patients with high SOFA scores, those receiving TPN therapy, and those who previously received antibacterial therapy. Renal failure and thrombocytopenia developing after candidemia should be followed carefully in patients. Antifungal therapy and removing the central venous catheter are essential in the management of candidemia

Aerococcus viridans Meningitis in a Patient with Hematological Malignancy: A Case Report

Aerococcus viridans, is commonly present in the environment as water, air, dust, soil and it can be rarely found in the flora of upper respiratory tract and skin. A. viridans, which has low virulence and pathogenity, may rarely cause endocarditis, bacteremia, meningitis, urinary tract infection, osteomyelitis, septic arthritis and wound infection. We report a case of meningitis caused by A. viridans in a 52 year-old male with chronic lymphocytic leukemia

Peritoneal Tuberculosis Presenting with Fever, Abdominal Pain and Diarrhea: Case Report

Tuberculous peritonitis may occur by spread from adjacent intraabdominal tuberculous diseases or haematogenously spread during miliary tuberculosis. Presenting symptoms are usually fever, abdominal pain, abdominal swelling and weight loss, diarrhea is not a common symptom. We report a patient with peritoneal tuberculosis who were presented with diarrhea, fever, abdominal pain and ascites. Mycobacterium tuberculosis was isolated from ascites. Peritoneal tuberculosis should be considered in patients presenting with fever, abdominal pain, diarrhea and ascites

Various Specialist Approaches for the Management of Candiduria: A Questionnaire Study

Introduction: Management of candiduria remains controversial, mainly due to uncertainties of clinicians about diagnosis and treatment. In this study, we aimed to investigate diagnostic and therapeutic approaches of different specialists for candiduria. Materials and Methods: An interview survey composed of 10 questions on candiduria was applied interactively to 429 randomly selected clinicians in six different tertiary care hospitals. We compared the answers of infectious diseases (ID) specialists with the others. Data were evaluated by Statistical package for Social Sciences version 11. In Independent samples, t-test and chi square test were performed for data analysis. Results: Out of the 429 participants, 91 (21.2%) were ID and 338 (78.8%) were specialists from other fi elds. For asymptomatic patients with candiduria, 213 (49.6%) participants stated that a second culture was required. Compared to others, a higher number of ID specialists [76 (83.5%)] asked for a second culture. It was determined that ID specialists joining this study, whose mean length of experience after specialization was longer than the others, encountered a signifi cantly higher number of candiduria cases and referred current guidelines to use frequently compared to others. Conclusion: Clinicians can treat candiduria largely, but have diffi culty in diagnosing. The fact that only 49.6% of all specialists included into the study order a second urine culture test shows that without differentiating colonization and contamination, half of them start therapies, which are likely to be unnecessary