33 research outputs found
Stable interference of EWSâFLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target
BACKGROUND: Ewing sarcoma is a paradigm of solid tumour -bearing chromosomal translocations resulting in fusion proteins that act as deregulated transcription factors. Ewing sarcoma translocations fuse the EWS gene with an ETS transcription factor, mainly FLI1. Most of the EWSâFLI1 target genes still remain unknown and many have been identified in heterologous model systems
Metastatic Behavior of the RIF-1 Murine Fibrosarcoma: Inhibited by Hypophysectomy and Partially Restored by Growth Hormone Replacement
Targeting of Insulin-Like Growth Factor Type 1 Receptor in Ewing Sarcoma: Unfulfilled Promise or a Promising Beginning?
Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas
1. The journal Cancer Research is the original source of the material.2. This article is hosted on a website external to the CBCRA Open Access Archive. Selecting âView/Openâ below will launch the full-text article in another browser window
Expression of CD31, Met/hepatocyte growth factor receptor and bone morphogenetic protein in bone metastasis of osteosarcoma
The Dialectic of the Spatial Determination of Capital: Rosa Luxemburg's Accumulation of Capital
Resistance Through Re-narration: Fanon on De-constructing Racialized Subjectivities
Frantz Fanon offers a lucid account of his entrance into the white world where the weightiness of the âwhite gazeâ nearly crushed him. In chapter five of Black Skins, White Masks, he develops his historico-racial and epidermal racial schemata as correctives to Merleau-Pontyâs overly inclusive corporeal schema. Experientially aware of the reality of socially constructed (racialized) subjectivities, Fanon uses his schemata to explain the creation, maintenance, and eventual rigidification of white-scripted âblacknessâ. Through a re-telling of his own experiences of racism, Fanon is able to show how a black person in a racialized context eventually internalizes the âwhite gazeâ. In this essay I bring Fanonâs insights into conversation with Foucaultâs discussion of panoptic surveillance. Although the internalization of the white narrative creates a situation in which external constraints are no longer needed, Fanon highlights both the historical contingency of âblacknessâ and the ways in which the oppressed can re-narrate their subjectivities. Lastly, I discuss Fanonâs historically attuned ânew humanismâ, once again engaging Fanon and Foucault as dialogue partners