254 research outputs found
Surgical Treatment for Biliary Carcinoma Arising After Pancreatoduodenectomy
The clinicopathological features and surgical treatment of biliary carcinoma around the major hepatic duct confluence arising after pancreatoduodenectomy (PD) due to initial bile duct carcinoma are described in three patients. Occurrence of biliary carcinoma more than 12 years after initial surgery and a histological finding of cholangiocellular carcinoma mixed with hepatocellular carcinoma suggested metachronous incidence of biliary carcinoma after PD. Extended right hemihepatectomy with complete removal of the residual extrahepatic bile duct and segmental, resection of the jejunal loop were carried out safely without operative death or severe postoperative complications. Two patients died of tumor recurrence 6 months after surgery, and the remaining patient is currently living a normal life without evidence of recurrence 17 months after surgery. These surgical procedures are a therapeutic option in patients with biliary carcinoma around the major hepatic duct confluence arising after PD
Immunohistochemical and Ultrastructural Analyses of Cytoplasmic Blood Plasma Inclusions of Rat Hepatocytes
In the present study, we investigated the histological, immunohistochemical and
ultrastructural characteristics of cytoplasmic blood plasma inclusions that spontaneously
occurred in a rat liver. Histologically, a number of cytoplasmic inclusions were observed
in the liver of an 8-week-old female SD rat. These inclusions were strongly positive for
PAS staining and resistant to diastase digestion. Immunohistochemical analyses revealed
that these inclusions were positive for albumin and IgG; however, most of them were
negative for LAMP-1 and LAMP-2. Ultrastructurally, the inclusions were surrounded by
limiting membranes and composed of moderately electron dense, homogenous materials. These
characteristics described here represent valuable information for pathological examination
in toxicity studies
Reasons for choosing extracurricular activities in junior high school studentsand their satisfaction
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