1 research outputs found
Divinylanthracene-Containing Tetracationic Organic Cyclophane with Near-Infrared Photoluminescence
Near-infrared
(NIR) light is known to have outstanding optical
penetration in biological tissues and to be non-invasive to cells
compared with visible light. These characteristics make NIR-specific
light optimal for numerous biological applications, such as the sensing
of biomolecules or in theranostics. Over the years, significant progress
has been achieved in the synthesis of fluorescent cyclophanes for
sensing, bioimaging, and making optoelectronic materials. The preparation
of NIR-emissive porphyrin-free cyclophanes is, however, still challenging.
In an attempt for fluorescence emissions to reach into the NIR spectral
region, employing organic tetracationic cyclophanes, we have inserted
two 9,10-divinylanthracene units between two of the pyridinium units
in cyclobis(paraquat-p-phenylene). Steady-state absorption,
fluorescence, and transient-absorption spectroscopies reveal the deep-red
and NIR photoluminescence of this cyclophane. This tetracationic cyclophane
is highly soluble in water and has been employed successfully as a
probe for live-cell imaging in a breast cancer cell line (MCF-7)