Analysis of road accidents fatalities: the impact of socio-economic factors and innovative solution strategies

In this work we present an experiment of guided innovation in the frame of the Innovation for Change program, where a group of students is called to solve a given challenge with innovative solutions, by applying methodological approaches throughout the all process. The problem under analysis is ‘road crash fatalities’, with a focus on the consequences of a poor post-crash care management. The solution is developed through a series of steps, such as problem definition, brainstorming sessions and interviews with stakeholders. Finally, the outputs of this process are presented as well as the designed solution, called EyeWay, which exploits already available technologies to perform automatic accident detection and shorten the crash notification time

Design of a Portable Microfluidic Platform for EGOT-Based in Liquid Biosensing

In biosensing applications, the exploitation of organic transistors gated via a liquid electrolyte has increased in the last years thanks to their enormous advantages in terms of sensitivity, low cost and power consumption. However, a practical aspect limiting the use of these devices in real applications is the contamination of the organic material, which represents an obstacle for the realization of a portable sensing platform based on electrolyte-gated organic transistors (EGOTs). In this work, a novel contamination-free microfluidic platform allowing differential measurements is presented and validated through finite element modeling simulations. The proposed design allows the exposure of the sensing electrode without contaminating the EGOT device during the whole sensing tests protocol. Furthermore, the platform is exploited to perform the detection of bovine serum albumin (BSA) as a validation test for the introduced differential protocol, demonstrating the capability to detect BSA at 1 pM concentration. The lack of contamination and the differential measurements provided in this work can be the first steps towards the realization of a reliable EGOT-based portable sensing instrument

A programmable culture platform for stimulation and in situ sensing of lung epithelial cells

A programmable dynamic cell culture chamber compatible with a standard multi-well plate was designed and characterized. The system is integrated with an array of OECT biosensors, in view of an in-situ monitoring of the dynamic cultures

Design of a contamination-free microfluidic device for Electrolyte-Gated Organic Field-Effect Transistor (EGOFET) biosensors

In this work a new microfluidic platform is designed and validated to remove analyte contamination problem in EGOFETs biosensors