10,771 research outputs found
Nash implementation with little communication
The paper considers the communication complexity (measured in bits or real numbers) of Nash implementation of social choice rules. A key distinction is whether we restrict to the traditional one-stage mechanisms or allow multi-stage mechanisms. For one-stage mechanisms, the paper shows that for a large and important subclass of monotonic choice rules -- called "intersection monotonic" -- the total message space size needed for one-stage Nash implementation is essentially the same as that needed for "verification" (with honest agents who are privately informed about their preferences). According to Segal (2007), the latter is the size of the space of minimally informative budget equilibria verifying the choice rule. However, multi-stage mechanisms allow a drastic reduction in communication complexity. Namely, for an important subclass of intersection-monotonic choice rules (which includes rules based on coalitional blocking such as exact or approximate Pareto efficiency, stability, and envy-free allocations) we propose a two-stage Nash implementation mechanism in which each agent announces no more than two alternatives plus one bit per agent in any play. Such two-stage mechanisms bring about an exponential reduction in the communication complexity of Nash implementation for discrete communication measured in bits, or a reduction from infinite- to low-dimensional continuous communication.Monotonic social choice rules, Nash implementation, communication complexity,verification, realization, budget sets, price equilibria
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Assessing stationary distributions derived from chromatin contact maps.
BACKGROUND:The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challenging due to compaction, dynamics and scale. However, a variety of recent assays, in particular Hi-C, have generated new details of chromatin structure, spawning a number of novel biological findings. Many findings have resulted from analyses on the level of native contact data as generated by the assays. Alternatively, reconstruction based approaches often proceed by first converting contact frequencies into distances, then generating a three dimensional (3D) chromatin configuration that best recapitulates these distances. Subsequent analyses can enrich contact level analyses via superposition of genomic attributes on the reconstruction. But, such advantages depend on the accuracy of the reconstruction which, absent gold standards, is inherently difficult to assess. Attempts at accuracy evaluation have relied on simulation and/or FISH imaging that typically features a handful of low resolution probes. While newly advanced multiplexed FISH imaging offers possibilities for refined 3D reconstruction accuracy evaluation, availability of such data is limited due to assay complexity and the resolution thereof is appreciably lower than the reconstructions being assessed. Accordingly, there is demand for new methods of reconstruction accuracy appraisal. RESULTS:Here we explore the potential of recently proposed stationary distributions, hereafter StatDns, derived from Hi-C contact matrices, to serve as a basis for reconstruction accuracy assessment. Current usage of such StatDns has focussed on the identification of highly interactive regions (HIRs): computationally defined regions of the genome purportedly involved in numerous long-range intra-chromosomal contacts. Consistent identification of HIRs would be informative with respect to inferred 3D architecture since the corresponding regions of the reconstruction would have an elevated number of k nearest neighbors (kNNs). More generally, we anticipate a monotone decreasing relationship between StatDn values and kNN distances. After initially evaluating the reproducibility of StatDns across replicate Hi-C data sets, we use this implied StatDn - kNN relationship to gauge the utility of StatDns for reconstruction validation, making recourse to both real and simulated examples. CONCLUSIONS:Our analyses demonstrate that, as constructed, StatDns do not provide a suitable measure for assessing the accuracy of 3D genome reconstructions. Whether this is attributable to specific choices surrounding normalization in defining StatDns or to the logic underlying their very formulation remains to be determined
Message and time efficient multi-broadcast schemes
We consider message and time efficient broadcasting and multi-broadcasting in
wireless ad-hoc networks, where a subset of nodes, each with a unique rumor,
wish to broadcast their rumors to all destinations while minimizing the total
number of transmissions and total time until all rumors arrive to their
destination. Under centralized settings, we introduce a novel approximation
algorithm that provides almost optimal results with respect to the number of
transmissions and total time, separately. Later on, we show how to efficiently
implement this algorithm under distributed settings, where the nodes have only
local information about their surroundings. In addition, we show multiple
approximation techniques based on the network collision detection capabilities
and explain how to calibrate the algorithms' parameters to produce optimal
results for time and messages.Comment: In Proceedings FOMC 2013, arXiv:1310.459
Models of Civil-Military Relationships at the Elite Level
http://deepblue.lib.umich.edu/bitstream/2027.42/50840/1/58.pd
Nonlinear thermal control in an N-terminal junction
We demonstrate control over heat flow in an N-terminal molecular junction.
Using simple model Hamiltonians we show that the heat current through two
terminals can be tuned, switched, and amplified, by the temperature and
coupling parameters of external gating reservoirs. We discuss two models: A
fully harmonic system, and a model incorporating anharmonic interactions. For
both models the control reservoirs induce thermal fluctuations of the
transition elements between molecular vibrational states. We find that a fully
harmonic model does not show any controllability, while for an anharmonic
system the conduction properties of the junction strongly depend on the
parameters of the gates. Realizations of the model system within nanodevices
and macromolecules are discussed
Mass Society and Non-Linear Development: A Study in Communication and Political Integration
http://deepblue.lib.umich.edu/bitstream/2027.42/50827/1/43.pd
Status Inconsistency, Cross Pressures, and American Political Behavior
http://deepblue.lib.umich.edu/bitstream/2027.42/50825/1/41.pd
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