Ortner sendromu' nun nadir bir nedeni: Behçet hastalığına sekonder gelişen dev pulmoner arter anevrizması

Behçet Hastalığı nedeni bilinmeyen sistemik bir otoimmün vaskülittir. Hem arterleri hem de venleri tutarak ciddi sorunlara neden olabilir. Kalp ve intratorasik büyük damarların patolojilerine bağlı olarak sol rekürren laringeal sinirin kompresyonu sonucu gelişen ses kısıklığı Ortner Sendromu olarak ifade edilir. Ortner Sendromu' nun en sık nedeni mitral darlığa bağlı olarak sol atriyum genişlemesidir. Çeşitli intratorasik patolojiler bu tablonun nedeni olabilir. Bununla birlikte Behçet Hastalığı sonucu gelişen pulmoner arter anevrizmasına bağlı Ortner Sendromu nispeten nadirdir. Biz burada ses kısıklığı ile başvuran ve yapılan incelemeler sonucunda Behçet Hastalığı' na bağlı dev pulmoner arter anevrizması sonucu gelişen Ortner Sendromu olarak tanı alan 78 yaşında bir bayan hastayı sunuyoruzBehçet' s disease is a systemic autoimmune vasculitis of unknown etiology. It causes serious disability by affecting both arteries and veins. Hoarseness due to compression of the left recurrent laringeus nerve resulting from pathologies of the heart and intrathoracic great vessels is defined as Ortner's syndrome. The most common cause of Ortner's syndrome is left atrial enlargement due to mitral stenosis. Various intrathoracic pathologies may also be the reason. Beside, Ortner's syndrome due to primary pulmonary artery aneurysm as a feature of Behçet's disease is relatively rare. Herein, we report a case of a 78 year old female patient presenting with hoarseness and diagnosed as Ortner's syndrome resulting from a giant pulmonary artery aneurysm secondary to Behçet' s disease. J Clin Exp Invest 2015; 6 (1): 69-7

The relationship between ischemia-modified albumin and myocardial infarction in on-pump coronary artery bypass grafting

Conclusion: Our study results show that IMA may be an early marker of myocardial infarction in the ONCABG patients

Oxidant-Antioxidant Balance during On-Pump Coronary Artery Bypass Grafting

Backround. The aim of this study was to evaluate the changes in perioperative oxidant-antioxidant balance in ONCABG. Methods. Twenty-three patients were included in this study. Serum total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) values were assessed preoperatively, at 20 minutes after aortic clamping and at 30 minutes, 6 hours, and 48 hours after declamping (reperfusion). The patients were divided into 2 groups according to the median aortic cross clamping (XC) time: group 1 (XC time < 42 minutes) and group 2 (XC time ≥ 42 minutes). Results. TOS and OSI values of whole patients at 30 minutes after reperfusion were higher than preoperative values (P=0.045, P=0.015), while perioperative TAS levels of the patients were similar to the preoperative levels (P=0.173). XC time was correlated with TOS levels at 30 minutes after reperfusion (r=0.43, P=0.041). In group 2, TOS and OSI values at 30 minutes after reperfusion were higher than preoperative values (P=0.023, P=0.048), whereas a significant difference was not found in group 1 (P=0.601, P=0.327). Conclusions. Oxidative imbalance and increase in TOS at reperfusion in ONCABG may be associated with XC time