Long-Term Outcomes of Chest Wall Resection in Non- Small Cell Lung Cancer in Geriatric Patients

Aim:Lung cancer has become a global health problem today. Both patients and physicians prefer oncologic treatment approaches rather than surgery in T3 and T4 lung cancers in the geriatric age group. The objective of this study was to assess the long-term survival outcomes of patients aged 70 years and older, who underwent chest wall resection due to non-small cell lung cancer, and the prognostic factors affecting morbidity.Methods:Eighteen patients, who underwent chest wall resection due to non-small cell lung cancer, were assessed retrospectively.Results:A total of 18 patients (16 male and 2 female) with a mean age of 74.28±3.81 years were included in the study. The most common surgery was right upper lobectomy (55.6%, n=10). Complications were detected in nine patients (50%). The most common complication was arrhythmia. Mortality was detected in four patients (22%). The mean two-year and five-year survival rates were 77.9% and 41.4%, respectively. Lymph node status, adjuvant treatment and tumor stage were prognostic factors affecting survival (p=0.001).Conclusion:Age should not be the only criterion for surgery. Appropriately selected patients should be offered anatomical resection. Long-term survival can be achieved in these patients

Tracheal adenoid cystic carcinoma masquerading asthma: A case report

BACKGROUND: Tracheal tumors are often misdiagnosed as asthma and are treated with inhaled steroids and bronchodilators without resolution. CASE PRESENTATION: Here, a patient with tracheal adenoid cystic carcinoma who had been previously diagnosed with difficult asthma was reported. The possibility of the presence of localized airway obstruction was raised when the flow-volume curve suggesting fixed airway obstruction, was obtained. CONCLUSION: The presenting case report emphasizes the fact that not all wheezes are asthma. It is critical to bear in mind that if a patient does not respond to appropriate anti-asthma therapy, localized obstructions should be ruled out before establishing the diagnosis of asthma

Normal kalp morfolojisine sahip iki kardeşte saptanan Levoatriyal Kardinal Ven

Levoatriyal kardinal ven (LACV), sol atriyum veya pulmoner venler ile kardinal venöz sistemden kaynaklananherhangi bir sistemik ven arasındaki anormal bağlantıdır. Çoğu zaman, bu anomali mitral atrezi veya hipoplastiksol kalp gibi sol taraflı obstrüktif kardiyak lezyonlar bağlamında tanımlanmıştır. Sol kalp patolojileri ve ek olarakçift çıkışlı sağ ventrikül, Fallot tetralojisi, ventriküler septal defekt ve atriyoventriküler septal defekt gibianomalilerle birlikte görüldüğü bildirilmiştir. Kardiyak anomali olmaksızın levoatriyal kardinal ven varlığısistemik venöz dönüşün çok nadir görülen bir konjenital anomalisidir. Literatürde asemptomatik olan ve ek birkardiyak anomalisi olmayan iki kardeşte LACV anomalisine rastlanmamıştır. Bu nedenle levoatrial kardinal ventanısı konulan ve ek kardiyak patolojisi olmayan iki kardeş olguyu ekokardiyografik bulgu, bilgisayarlı tomografi(BT) ve aniografik görüntüleri ile sunmayı amaçladıkAnahtar Kelimeler: ASEMPTOMATIK LEVOATRIYAL KARDINAL VEN,NORMAL KALP,İKİ KARDEŞ</p

Taktik insansız hava aracı tasarımı ve üretimi

TÜBİTAK MAG15.08.2012Proje kapsamında taktik bir insansız hava aracı tasarımı ve üretimi gerçekleştirilmiştir. Hava aracı bütünü ile kompozit malzemeden üretilmiştir. Hava aracı üretimi için gerekli olan bütün kalıplar da proje kapsamında Havacılık ve Uzay Mühendisliği Bölümü prototip atelyesinde üretilmiş ve proje sayesinde çok önemli bir üretim kabiliyeti sağlanmıştır. Hava aracının bütün mekanik ve elektromekanik sistem entegrasyonu başarı ile tamamlanmıştır. Hava aracına takılı bir kamera ve verici sistemi vasıtası ile gerçek zamanlı görüntü aktarımı yer testleri sırasında sağlanmıştır. Yer testleri başarı ile gerçekleştirilmiş ve hava aracı tasarımında iyileştirmesi gereken noktalar saptanmıştır. Bir sonraki adımda belirlenen tasarım iyileştirmeleri yapıldıktan sonra uçuş denemelerine geçilecektir

Investigation of Serum Interleukin 6, High-Sensitivity C-Reactive Protein and White Blood Cell Levels during the Diagnosis and Treatment of Paediatric Appendicitis Patients Before and during the COVID-19 Pandemic

Introduction: In this study, we prospectively investigated changes in serum interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP) and full white blood cell (WBC) counts during the diagnosis and treatment of paediatric patients with appendicitis. We also investigated the effects of the COVID-19 pandemic on the diagnosis and treatment processes of paediatric appendicitis patients. Materials and Methods: A non-perforated appendicitis group (n = 110), a perforated appendicitis group (n = 35) and an appendicitis + COVID-19 group (n = 8) were formed. Blood samples were taken upon admission and every day until the three studied parameters returned to normal values. To investigate the effects of the COVID-19 pandemic on paediatric appendicitis patients, the perforated appendicitis rates and the times from the onset of the first symptoms to the operation before and during the pandemic were compared. Results: WBC, IL-6, and hsCRP dropped below the upper limits on the second postoperative day in the non-perforated appendicitis group, four to six days postoperatively in the perforated appendicitis group, and three to six days postoperatively in the appendicitis + COVID-19 group. These parameters were not within normal range in patients who developed complications during follow-up. The time from the onset of abdominal pain to the surgery was significantly longer during than before the pandemic in both the non-perforated appendicitis group and the perforated appendicitis group. Conclusions: Our results show that WBC, IL-6, and hsCRP are useful laboratory parameters that can complete clinical examinations in the diagnosis of appendicitis in paediatric patients and the identification of complications that may develop postoperatively

Piccolo in transcatheter PDA closure multi-centre study from premature to adolescent children.

In this multi-centre study, the mid- to long-term efficacy and safety of the Amplatzer Piccolo Occluder in patent ductus arteriosus closure in premature and term infants as well as children were discussed. Methods. Between 2016 and 2021, 645 patients, 152 of whom were less than 1 month old, underwent ductus closure with the Piccolo device from five different centres in Turkey. The median age of the patients was 2.2 years, and the mean narrowest point of duct diameter was 1.8 mm. Sixty-two patients weighed ≤ 1.5 kg, 90 patients 1.5-3 kg, and the mean follow-up was 20.4 months. In 396, the duct was closed by the retrograde route. Ductal anatomy was Type A in 285, C in 72, E in 171, and F in 64 patients. Fluoroscopy duration was 6.2 min. The procedure success rate was 99.1%. Device embolisation occurred in 13 patients (2%), and 11 were retrieved with a snare. Cardiac perforation and death developed in one premature baby. The left pulmonary artery and the descending aorta stenosis were observed in 3 (0.4%) and in 5 patients (0.5%). Results. Piccolo device is safe and effective in closing ductus in all age groups. It has low profile for use in premature and newborn babies, a small embolisation risk, and a low residual shunt rate after closure. Conclusion. The Piccolo device can be considered as close an ideal occluder. The lower profile, smaller delivery catheter size, and symmetry of this device allow for a venous or arterial approach

Is there any relationship between proinflammatory mediator levels in disc material and myelopathy with cervical disc herniation and spondylosis? A non-randomized, prospective clinical study

The proinflammatory mediator (PIM) levels were assessed in surgically removed samples of herniated cervical intervertebral discs. The objective of this study was to investigate if there is a correlation between the levels of PIMs in disc material and myelopathy associated with cervical intervertebral disc herniation and spondylosis. The role of proinflammatory mediators in the degeneration of intervertebral disc and the inflammatory effects of disc herniations on radicular pain has been previously published. However, the possible relationship between PIMs and myelopathy related to cervical disc herniation and spondylosis has not been investigated before. Thirty-two patients undergoing surgery for cervical disc herniation and spondylosis were investigated. Surgically obtained disc materials, stored at 70°C, were classified into two groups: cervical disc herniation alone or with myelopathy. Biochemical preparation and solid phase enzyme amplified sensitivity immunoassay (ELISIA) analysis of the samples were performed to assess the concentration of mediators in the samples. Very similar values of interleukin-6 were found in both groups whereas the concentrations of mediators were significantly higher in myelopathy group. This study has demonstrated that PIMs are involved in cervical intervertebral disc degeneration with higher concentrations in the samples associated with myelopathy