Long-Term Outcomes of Chest Wall Resection in Non- Small Cell Lung Cancer in Geriatric Patients

Aim:Lung cancer has become a global health problem today. Both patients and physicians prefer oncologic treatment approaches rather than surgery in T3 and T4 lung cancers in the geriatric age group. The objective of this study was to assess the long-term survival outcomes of patients aged 70 years and older, who underwent chest wall resection due to non-small cell lung cancer, and the prognostic factors affecting morbidity.Methods:Eighteen patients, who underwent chest wall resection due to non-small cell lung cancer, were assessed retrospectively.Results:A total of 18 patients (16 male and 2 female) with a mean age of 74.28±3.81 years were included in the study. The most common surgery was right upper lobectomy (55.6%, n=10). Complications were detected in nine patients (50%). The most common complication was arrhythmia. Mortality was detected in four patients (22%). The mean two-year and five-year survival rates were 77.9% and 41.4%, respectively. Lymph node status, adjuvant treatment and tumor stage were prognostic factors affecting survival (p=0.001).Conclusion:Age should not be the only criterion for surgery. Appropriately selected patients should be offered anatomical resection. Long-term survival can be achieved in these patients

Tracheal adenoid cystic carcinoma masquerading asthma: A case report

BACKGROUND: Tracheal tumors are often misdiagnosed as asthma and are treated with inhaled steroids and bronchodilators without resolution. CASE PRESENTATION: Here, a patient with tracheal adenoid cystic carcinoma who had been previously diagnosed with difficult asthma was reported. The possibility of the presence of localized airway obstruction was raised when the flow-volume curve suggesting fixed airway obstruction, was obtained. CONCLUSION: The presenting case report emphasizes the fact that not all wheezes are asthma. It is critical to bear in mind that if a patient does not respond to appropriate anti-asthma therapy, localized obstructions should be ruled out before establishing the diagnosis of asthma

Optimization of Drying Parameters to Maximize Antioxidant Activity, Total Phenolic and Anthocyanin Content of Purple Carrot Puree Powder

Abstract Purple carrots are an important source of phenolic compounds and spray drying is the most advantageous method to make purple carrots more stable. Optimization analysis was carried out to determine the effects of inlet temperature, pump rate, and maltodextrin concentration on the process yield, antioxidant activity, total phenolic and anthocyanin content in the purple carrot puree powder. The optimum drying parameters obtained by maximizing the dependent variables (desirability = 0.809) were determined to be 16.51% (w/v) maltodextrin concentration, 180.16°C inlet temperature, and 30.39% pump rate. Process yield was found to be 83.64%. In recommended optimum conditions, the dependent variables were determined to be, 81.20% DPPH scavenging antioxidant activity, 5332.87 ppm total phenolic content as gallic acid equivalent, and 449.71 ppm total anthocyanin content as cyanidin-3-glucoside. These findings indicate that under the recommended conditions, they were preserved at 92.66%, 90.43%, and 83.79%, respectively.</jats:p

Control of Browning, Enzyme Activity, and Quality in Stored Fresh-cut Fruit Salads through Chitosan Coating Enriched with Bergamot Juice Powder

In this study, fresh-cut fruit salads composed of apples, pears, kiwis, and pineapples were stored at +4 &deg;C for 18 days under distinct conditions: non-coated (NC), chitosan-coated (CH), and bergamot juice powder extract-enriched chitosan-coated (CHBE). Storage endpoint decay percentages were as follows: NC group: 100%, CH group: 26.67&ndash;53.3%, CHBE group: 13.33&ndash;26.67%. CHBE had the highest moisture content (87.05&ndash;89.64%), soluble solids (12.40&ndash;13.26%), and chroma values (2.35&ndash;6.60). CHBE and NC groups had 2.10% and 6.61% weight loss, respectively. The NC group had the highest polyphenol oxidase activity (19.48 U mL&minus;1) and browning index (0.70 A420/g); CH group: 0.85 U mL&minus;1, 0.35 A420/g; CHBE group: 0.57 U mL&minus;1, 0.27 A420/g. CHBE showed a titratable acidity of 1.33% and pH 3.73 post-storage, impeding microbial proliferation with the lowest counts (2.30&ndash;3.24 log CFU g&minus;1). The microbial suitability of the NC group diminished after day 6, with an overall preference score of 1.00. Conversely, the CH and CHBE groups scored 3.15 and 4.56, highlighting the coatings&rsquo; effectiveness. Bergamot juice powder extract further enhanced this, mitigating browning and enhancing quality. Results reveal tailored coatings&rsquo; potential to extend shelf life, improve quality, and enhance fruit salads&rsquo; acceptability. This study underscores the importance of edible coatings in addressing preservation challenges, emphasizing their role in enhancing food quality and consumer acceptability. Incorporating edible coatings is pivotal in mitigating deterioration issues and ensuring the overall success of fresh-cut fruit products in the market