COSELMAR. Compréhension des socio-écosystèmes littoraux et marins pour la prévention et la gestion des risques. Bilan scientifique 2013-2017

COSELMAR, a 4-year project financed by the Région des Pays de la Loire at 2.1 M€, officially started on the 7th January 2013. The project is coordinated by Philipp Hess (IFREMER) and Sophie Pardo (Université de Nantes-LEMNA) and falls under the Federation for Research Institut Universitaire Mer et Littoral (IUML, FR CNRS 3473)*. COSELMAR has also been approved by the Scientific Council of the MSH Ange Guépin. COSELMAR is a research project uniting 5 research units of IFREMER and 11 laboratories of the Université de Nantes, along with academic partners, and national and international industries. The aim is to achieve a better understanding of the marine and coastal ecosystems and the associated resources. The project will also provide insights into risk management and prevention of natural events and anthropogenic impacts. COSELMAR’s main objective is to integrate and promote the interdisciplinary scientific work concerning the issues above in order to build a real expertise on potential risks of coastal and marine zones. The project is divided into 3 axes of research and 1 integrated axis:Le projet COSELMAR, financé par la Région des Pays de la Loire à hauteur de 2.1 M€ pour une durée de 4 ans, a commencé officiellement le 07  janvier 2013. Coordonné par Philipp Hess (IFREMER) et Sophie Pardo (Université de Nantes-LEMNA), il est un projet fédérateur pour la Fédération de Recherche Institut Universitaire Mer et Littoral (IUML, FR CNRS 3473)*.  COSELMAR a également été agréé par le Conseil Scientifique de la MSH Ange Guépin. Cinq  unités de recherches de l’IFREMER et onze  laboratoires de l’Université de Nantes, appuyés par des partenariats académiques et industriels français et internationaux vont collaborer afin d'apporter une meilleure compréhension des écosystèmes littoraux et marins et des ressources associées, ainsi qu'une réflexion sur la gestion et la prévention des risques engendrés par les facteurs naturels et anthropiques. L'objectif principal de COSELMAR est d'intégrer des travaux scientifiques interdisciplinaires autour de ces questions afin de construire une véritable expertise sur les risques en milieu littoral et marin. Ce projet est divisé en trois axes de recherche et un axe intégrateur :  

Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

International audienceThe aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed