Compton scattering beyond the impulse approximation

We treat the non-relativistic Compton scattering process in which an incoming photon scatters from an N-electron many-body state to yield an outgoing photon and a recoil electron, without invoking the commonly used frameworks of either the impulse approximation (IA) or the independent particle model (IPM). An expression for the associated triple differential scattering cross section is obtained in terms of Dyson orbitals, which give the overlap amplitudes between the N-electron initial state and the (N-1) electron singly ionized quantum states of the target. We show how in the high energy transfer regime, one can recover from our general formalism the standard IA based formula for the cross section which involves the ground state electron momentum density (EMD) of the initial state. Our formalism will permit the analysis and interpretation of electronic transitions in correlated electron systems via inelastic x-ray scattering (IXS) spectroscopy beyond the constraints of the IA and the IPM.Comment: 7 pages, 1 figur

A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance

Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types, including basal stem cells, mucus-secreting goblet cells, motile ciliated cells, cystic fibrosis transmembrane conductance regulator (CFTR)-rich ionocytes, and immune cells1,2. Bronchiectasis, a syndrome of pathological airway dilation associated with impaired mucociliary clearance, may occur sporadically or as a consequence of Mendelian inheritance, for example in cystic fibrosis, primary ciliary dyskinesia (PCD), and select immunodeficiencies3. Previous studies have identified mutations that affect ciliary structure and nucleation in PCD4, but the regulation of mucociliary transport remains incompletely understood, and therapeutic targets for its modulation are lacking. Here we identify a bronchiectasis syndrome caused by mutations that inactivate NIMA-related kinase 10 (NEK10), a protein kinase with previously unknown in vivo functions in mammals. Genetically modified primary human airway cultures establish NEK10 as a ciliated-cell-specific kinase whose activity regulates the motile ciliary proteome to promote ciliary length and mucociliary transport but which is dispensable for normal ciliary number, radial structure, and beat frequency. Together, these data identify a novel and likely targetable signaling axis that controls motile ciliary function in humans and has potential implications for other respiratory disorders that are characterized by impaired mucociliary clearance

Psychology and aggression

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68264/2/10.1177_002200275900300301.pd

Comparison of resilience of different plant teams to drought and temperature extremes in Denmark in sole and intercropping systems

Intercropping (IC) can reduce nitrogen fertilizer requirements, supress weeds, and improve crop yields and yield stability. Three field trials were conducted in Denmark in 2018 with intercropping and sole crops (SC) using spring wheat, barley, faba bean and field pea to compare productivity under five fertilizer levels. The trials were carried out using in a split-plot design with four. Anomalous weather during the 2018 cropping season created drought conditions and high temperatures above 31°C. No effect of fertilizer treatment was found, and total dry matter and grain yields were supressed in all systems. Wheat grain yields averaged 2.14 t ha−1 across systems, ranging from 1.58 t ha−1 as a component of the IC to 2.44 t ha−1 as SC, and barley grain yields averaged 2.35 t ha−1. Faba bean yielded 1.78 t ha−1 as SC, but failed in the IC. Pea failed in both systems. Intercropping barley with cover crops had no effect on grain yield or total dry matter. These results suggest that intercropping provided no production advantage during a drought and illuminate the need to continue conducting research and breeding on drought-resistant cultivars