Minimal underlying data.

(XLSX)</p

Change of daily process measures over the study period among the whole cohort and in subgroups of ICUs with baseline spontaneous trial (SAT) compliance of >50% and ≤50.

(PDF)</p

Outcomes.

Outcomes.</p

Map of Saudi Arabia with distribution of participating ICUs.

(PDF)</p

Distribution of compliance, non-compliance and contraindications (with reasons) to the interventions.

(PDF)</p

S2 File -

(PDF)</p

The Saudi Critical Care Trials Group.

(PDF)</p

Change of ICU mortality and ventilator-associated events (VAE) over the study period among the whole cohort and in subgroups of ICUs with baseline spontaneous trial (SAT) compliance of >50% and ≤50%.

(PDF)</p

Daily care process measures.

Daily care process measures.</p

List of participating sites and ethics committee approvals.

(PDF)</p