6 research outputs found
NADPH-dependent clearance and transformation of 5ESL to 5ESLO in liver microsomes from four species of butterflyfish and recombinant human CYP3A4.
<p>Different letters indicate significant (P ≤ 0.05) differences between species* indicated signifcnat differences between control and pretreated <i>C</i>. <i>unimaculatus</i> (P ≤ 0.05) (N = 6–8).</p
The percentage survival of butterflyfish after a 7 day oral exposure to high dose (3.0mg/kg), or low dose (1.0mg/kg) of 5ESL.
<p>Each value represents the total survival of 6–8 individuals.</p
Effects of dietary exposure to <i>S</i>.<i>maxima</i> tissue homogenate on the hepatic content CYP2K1-like and CYP2M1-like (A, B) and catalytic activity (C) of and CYP2 in four species of butterflyfish.
<p>Different letters indicate significant (P ≤ 0.05) differences between untreated and treated fish (N = 6–8).</p
Effects of dietary exposure to 5ESL on the hepatic content of CYP2M1-like protein (A) and catalytic activity (B) of and CYP2 in four species of butterflyfish.
<p>Different letters indicate significant (P ≤ 0.05) differences between untreated and treated fish (N = 6–8).</p
Structures of 5ESL (A) of <i>S</i>. <i>maxima</i> and 5ESL 15,16 epoxide (5ESLO) (B).
<p>Structures of 5ESL (A) of <i>S</i>. <i>maxima</i> and 5ESL 15,16 epoxide (5ESLO) (B).</p
Effects of dietary exposure to <i>S</i>.<i>maxima</i> tissue homogenate on the hepatic content (A) and catalytic activity (B, C) of and CYP3A in four species of butterflyfish.
<p>Different letters indicate significant (P ≤ 0.05) differences between untreated and treated fish (N = 6–8).</p