Individual and area-level attributes by stage at diagnosis, esophageal adenocarcinoma incident cases, SEER Registries, 2000-2007.

<p>Individual and area-level attributes by stage at diagnosis, esophageal adenocarcinoma incident cases, SEER Registries, 2000-2007.</p

Associations between stage at diagnosis and case attributes, esophageal adenocarcinoma incident cases, SEER Registries, 2000-2007.

<p>^† Adjusted for age, sex, race, and year of diagnosis</p><p>* Includes all races and ethnicities combined excluding whites</p

Modeled United States county-level hepatocellular carcinoma incidence rates, 2000–2009.

<p>Modeled United States county-level hepatocellular carcinoma incidence rates, 2000–2009.</p

Modeled United States county-level intrahepatic cholangiocarcinoma incidence rates, 2000–2009.

<p>Modeled United States county-level intrahepatic cholangiocarcinoma incidence rates, 2000–2009.</p

Modeled age-adjusted hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma incidence rates per 100,000; 2000–2009 by demographic group.

<p>^aAll races are non-Hispanic.</p><p>Modeled age-adjusted hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma incidence rates per 100,000; 2000–2009 by demographic group.</p

Hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma incidence trends, 1998–2009.

<p>^aAPC = annual percent change.</p><p>^bAAPC = average annual percent change.</p><p>*Significant at p<0.05.</p><p>Hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma incidence trends, 1998–2009.</p

Adjusted¹ logistic regression analysis examining the association between selected medical conditions and ICC or ECC, SEER-Medicare 2000–2011.

<p>Adjusted<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0186643#t004fn001" target="_blank">¹</a> logistic regression analysis examining the association between selected medical conditions and ICC or ECC, SEER-Medicare 2000–2011.</p

International Classification of Diseases, ninth edition codes for preexisting medical conditions and risk factors for cholangiocarcinoma.

<p>International Classification of Diseases, ninth edition codes for preexisting medical conditions and risk factors for cholangiocarcinoma.</p

Demographic characteristics of the study participants, SEER-Medicare 2000–2011.

<p>Demographic characteristics of the study participants, SEER-Medicare 2000–2011.</p

Comparison of preexisting medical conditions among ICC cases, ECC cases, and controls, SEER-Medicare 2000–2011¹.

<p>Comparison of preexisting medical conditions among ICC cases, ECC cases, and controls, SEER-Medicare 2000–2011<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0186643#t003fn001" target="_blank">¹</a>.</p