Office technology : a determinant in the organization of spaces

Technological advances have initiated complexity in buildings and may also provide the means to manage it. Research in advanced technology development suggests new directions for development and application of advanced technologies to buildings. The purpose of this research is to examine and develop an understanding of building related computer uses. This study is done by literature search and field survey. Through literature search the theoretical background is established. Through field survey practical guidelines are suggested. Studies of social and physical organizational systems and building systems are surveyed, then computers and advanced technologies are introduced. This is to find out practical applications and examples. The research then focuses on a detailed example of relationship between buildings and advanced technologies. This is based on interview and questionnaire information from four different companies. The work concludes with guidelines on how buildings and advanced technologies can and should relate to each other

A serpentine laminating micromixer combining splitting/recombination and advection

Mixing enhancement has drawn great attention from designers of micromixers, since the flow in a microchannel is usually characterized by a low Reynolds number ( Re) which makes the mixing quite a difficult task to accomplish. In this paper, a novel integrated efficient micromixer named serpentine laminating micromixer (SLM) has been designed, simulated, fabricated and fully characterized. In the SLM, a high level of efficient mixing can be achieved by combining two general chaotic mixing mechanisms: splitting/recombination and chaotic advection. The splitting and recombination ( in other terms, lamination) mechanism is obtained by the successive arrangement of "F''-shape mixing units in two layers. The advection is induced by the overall three-dimensional serpentine path of the microchannel. The SLM was realized by SU-8 photolithography, nickel electroplating, injection molding and thermal bonding. Mixing performance of the SLM was fully characterized numerically and experimentally. The numerical mixing simulations show that the advection acts favorably to realize the ideal vertical lamination of fluid flow. The mixing experiments based on an average mixing color intensity change of phenolphthalein show a high level of mixing performance was obtained with the SLM. Numerical and experimental results confirm that efficient mixing is successfully achieved from the SLM over the wide range of Re. Due to the simple and mass producible geometry of the efficient micromixer, SLM proposed in this study, the SLM can be easily applied to integrated microfluidic systems, such as micro-total-analysis-systems or lab-on-a-chip systems.X11159165sciescopu

Rotting infinitely many-armed bandits

We consider the infinitely many-armed bandit problem with rotting rewards, where the mean reward of an arm decreases at each pull of the arm according to an arbitrary trend with maximum rotting rate ϱ=o(1). We show that this learning problem has an Ω(max{ϱ1/3T,T−−√}) worst-case regret lower bound where T is the time horizon. We show that a matching upper bound O~(max{ϱ1/3T,T−−√}), up to a poly-logarithmic factor, can be achieved by an algorithm that uses a UCB index for each arm and a threshold value to decide whether to continue pulling an arm or remove the arm from further consideration, when the algorithm knows the value of the maximum rotting rate ϱ. We also show that an O~(max{ϱ1/3T,T3/4}) regret upper bound can be achieved by an algorithm that does not know the value of ϱ, by using an adaptive UCB index along with an adaptive threshold value

Contextual Linear Bandits under Noisy Features: Towards Bayesian Oracles

We study contextual linear bandit problems under uncertainty on features; they are noisy with missing entries. To address the challenges from the noise, we analyze Bayesian oracles given observed noisy features. Our Bayesian analysis finds that the optimal hypothesis can be far from the underlying realizability function, depending on noise characteristics, which is highly non-intuitive and does not occur for classical noiseless setups. This implies that classical approaches cannot guarantee a non-trivial regret bound. We thus propose an algorithm aiming at the Bayesian oracle from observed information under this model, achieving $\tilde{O}(d\sqrt{T})$ regret bound with respect to feature dimension $d$ and time horizon $T$. We demonstrate the proposed algorithm using synthetic and real-world datasets.Comment: 30 page

Method of Extracting Is-A and Part-Of Relations Using Pattern Pairs in Mass Corpus

PACLIC 23 / City University of Hong Kong / 3-5 December 200

Disposable Integrated Microfluidic Biochip for Blood Typing by Plastic Microinjection Moulding

Blood typing is the most important test for both transfusion recipients and blood donors. In this paper, a low cost disposable blood typing integrated microfluidic biochip has been designed, fabricated and characterized. In the biochip, flow splitting microchannels, chaotic micromixers, reaction microchambers and detection microfilters are fully integrated. The loaded sample blood can be divided by 2 or 4 equal volumes through the flow splitting microchannel so that one can perform 2 or 4 blood agglutination tests in parallel. For the purpose of obtaining efficient reaction of agglutinogens on red blood cells (RBCs) and agglutinins in serum, we incorporated a serpentine laminating micromixer into the biochip, which combines two chaotic mixing mechanisms of splitting/recombination and chaotic advection. Relatively large area reaction microchambers were also introduced for the sake of keeping the mixture of the sample blood and serum during the reaction time before filtering. The gradually decreasing multi-step detection microfilters were designed in order to effectively filter the reacted agglutinated RBCs, which show the corresponding blood group. To achieve the cost-effectiveness of the microfluidic biochip for disposability, the biochip was realized by the microinjection moulding of COC (cyclic olefin copolymer) and thermal bonding of two injection moulded COC substrates in mass production with a total fabrication time of less than 20 min. Mould inserts of the biochip for the microinjection moulding were fabricated by SU-8 photolithography and the subsequent nickel electroplating process. Human blood groups of A, B and AB have been successfully determined with the naked eye, with 3 mu l of the whole sample bloods, by means of the fabricated biochip within 3 min.X11100104sciescopu

Management of Adult Blunt Renal Injury: A 10-Year Retrospective Review at a Single Institution

Purpose Renal injury occurs in up to 5% of trauma cases and the kidney is the third most wounded abdominal organ. The study objective was to analyze clinical characteristics of patients with blunt renal trauma and review the treatment of high-grade blunt renal injuries. Methods The medical charts of trauma patients who visited Haeundae Paik Hospital between March 2010 and February 2020 were retrospectively analyzed. Data on demographics, injury patterns, clinical presentation, management, and outcomes were analyzed. Results A total of 68 patients with renal trauma were included in this study. The most common renal injury was Grade III (n = 27, 39.7%). Falling was the predominant mechanism of injury (n = 33, 48.5%), and 23.5% (n = 16) of patients sustained isolated renal trauma. Organ damage related to kidney injury included chest injury (57.4%, n = 39) and abdominal or pelvic content injury (48.5%, n = 33). The overall mortality rate was 2.9% (n = 2). There were 45 cases of high-grade renal trauma (AAST Kidney injury scale Grade III–V). There was no statistical difference in the outcomes of high-grade (n = 44, 97.8%) and low-grade (n = 23, 100%) renal trauma patients who received nonoperative treatment (p = 0.511). Variables did not differ significantly, except for the injury severity score which was statistically significantly different between low-grade and high-grade renal trauma patients (p = 0.001). Conclusion Most patients with traumatic renal injury, even those with high-grade injury, can be managed by nonoperative treatment, and have a good prognosis

Hybrid XML Data Model Architecture for Efficient Document Management

XML has been known as a document standard in representation and exchange of data on the Internet, and is also used as a standard language for the search and reuse of scattered documents on the Internet. The issues related to XML are how to model data on effective and efficient management of semi-structured data and how to actually store the modeled data when implementing a XML contents management system. Previous researches on XML have limitations in (1) reproduction of XML documents from the stored data, (2) retrieval of XML sub-graph from search, (3) supporting only top-down search, not full-search, and (4) dependency of data structure on XML documents. The purpose of this paper is to present a hybrid XML data model architecture for the storage and search of XML document data. By representing both data and structure views of XML documents, this new XML data model technique overcomes the limitations of previous researches on data model for XML documents as well as the existing database systems such as relational and object-oriented data model

Cyclooxygenase-2 and p53 Expression as Prognostic Indicators in Conventional Renal Cell Carcinoma

The aim of this study was to investigate the relationship of cyclooxygenase (COX)-2 and p53 expression with prognosis in patients with conventional renal cell carcinoma (RCC). Formalin-fixed, paraffin-embedded tissue sections of conventional RCC from 92 patients, who had undergone radical nephrectomy, were examined for COX-2 and p53 expression by immunohistochemistry and compared with clinicopathological variables. The COX-2 expression significantly correlated only with tumor size (p=0.049), whereas the p53 expression profoundly correlated with the TNM stage (p=0.024), M stage (p=0.001), and metastasis (synchronous or metachronous; p=0.004). The COX-2 overexpression did not significantly associate with p53 positivity (p=0.821). The survival rate of patients correlated with the p53 expression (p<0.0001) but not with the COX-2 expression (p=0.7506). Multivariate analyses indicated that tumor size, M stage, and p53 expression were independent prognostic factors for cancer-specific survival. The COX-2 expression was not an independent factor. These results show that the increased expression of p53 was associated with metastasis and a worse prognosis in conventional RCC, which suggests that p53 might have played an important role in the progression of conventional RCC. The increased expression of COX-2 was associated only with tumor size, but may not be an important prognostic factor in conventional RCC. No association was observed between COX-2 overexpression and p53 positivity in conventional RCC