3,060 research outputs found
Do You See What I See: Comparing Student and Librarian Perceptions of Learning Outcomes
In 2009 the Research and Instructional Services Department at Raynor Memorial Libraries at Marquette University, began using the Association of College & Research Libraries (ACRL) Information Literacy Competency Standards for Higher Education to track and assess the information literacy competencies of instructional sessions. Instructional sessions were entered into a locally developed database and mapped to the ACRL information literacy standard(s) addressed in each session, as perceived by the librarian. Students who participated in a research consultation session were surveyed on their perception of the information literacy standards addressed in the session and overall effectiveness of the session. Responses from the students and librarians were collected and correlated for an in-depth look at information literacy standards in research consultations conducted in 2010
Redefining Exhaustion: Considerations for the Modeling of Critical Power
Background: The relationship between exercise intensity and the limit of tolerance is the focus of the Critical Power (CP) model. CP defines the upper limit for which exercise is steady state and is – in theory – indefinitely sustainable. However, this limit of tolerance at CP is often well below 30 min. Purpose: We want to test the hypothesis that 1) a clinically significant residual W’ capacity (W’res) does exist, 2) that the size of W’res is inversely related to tlim used in the testing protocols, and 3) that accounting for W’res will result in an improved calculation of the Critical Power (CP), as determined by an increased time to exhaustion at CP. Methods: Nine well-trained cyclists performed a ramp test and four high-intensity tests to exhaustion on a cycle ergometer to determine CP and the curvature constant (W’). Two tests to exhaustion were then performed at the traditional CP (CPtrad) and a novel, modified CP (CPmod) to test the practical significance of the residual capacity on the calculation of the CP. Results: All participants were able to perform work above CP even after reaching the limit of tolerance, despite no significant changes in physiological parameters. Including the W’res resulted in significantly lower estimations of CP (TRAD: 281W, MOD: 278 W; p = 0.015) and higher estimations of W’ (TRAD: 15.8 kJ, MOD: 17.8 kJ; p = 0.008). Significance: Athletes were able to continue generating power above CP, even after reaching the limit of tolerance. This residual capacity resulted in a significantly lower estimate of CP and significantly higher estimation of W’
Tsuki no Shirabe for flute and koto
Title from PDF of title page, viewed on March 23, 2016Thesis advisor: James MobberleyVitaIncludes bibliographical references (page 34)Thesis (M.M.)--Conservatory of Music And Dance. University of Missouri--Kansas City, 2015Tsuki no Shirabe was composed at the request of Jun Aita-san to
commemorate her 60th birthday of her mother, Michiko Saito-san. I
asked to compose music that is both reminiscent of Japanese music and
aesthetics, and also sounds like my own. The challenge was to strike a
balance that respects the rich musical tradition of Japan, while never
resorting to mere exoticism.
The piece consists of six parts all performed without pause,
forming a large, musical narrative. The themes are cyclical, and are
developed in ways biographical to the life of Saito-san. In the
kumiuta tradition of art song with koto, the performer both sings and
accompanies herself. In keeping with this, texts were carefully
selected to reflect periods of her life.Abstract -- Text and translations -- Performance notes -- Score -- Vita -- Bibliograph
Completion Report: Arkansas State Pesticides in Ground Water Monitoring Project Phase V: Vulnerable areas in Jackson, Monroe, Lawrence and Lonoke Counties
In 1996, sixty-seven water samples were drawn from 65 wells, including 62 new wells and 3 wells sampled previously . One Woodruff County well and two Pulaski County wells were resampled. Thirty-two samples were drawn from 30 wells in Monroe County (well #1 was sampled 3 times during this phase) . Ten wells in Jackson County, 12 wells in Lawrence County and 10 wells in Lonoke were also tested (Figures 1-5) . With the completion of Phase V, the number of wells tested has risen to 231 with a total of 258 samples analyzed . Initially, the wells were tested for 13 pesticides and ni~rate. Two more pesticides, aldicarb and carbofuran were added to the analyte list during Phase V. The analyte list is shown in Table 3 . All results from all the wells are listed in Appendix A. Quality control information for these data follow the results. The Phase V Quality Assurance Report is included in this document as Part II
Animal Waste and the Land-Water Interface
This book presents abstracts of research studies conducted on animal wastes and the interface between application of animal waste to land. The abstracts were divided into sections which tend to organize summaries of research studies conducted on similar topics. These topics range from characteristics of animal waste to the effects of animal wastes on streams, lakes, wetlands, and watersheds, development of best management practices, nutrient management, edge of field losses and alternative uses. The posters will be available for viewing from 10:00 a.m. Monday, July 17, until 12:00 noon on Wednesday, July 19, 1995
Ground Water Monitoring Project for Arkansas, Phase III
This report is composed of two parts. The first part is an interpretation of the pesticide and nitrate data collected in Woodruff County based on samples collected during 1994. Because there is an indication that there were hydrological differences between 1994 and 1995, and because most of the pesticide data is from 1994, this interpretive portion is restricted to 1994 data. Six wells initially sampled in 1994 that contained pesticides had continuing contamination in re-sampling in 1994 and 1995. Part II lists a seventh well in Woodruff County that contained pesticides in February and May of 199
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The Future of The COSPAR Planetary Protection Guidelines: Space Governance and Astrobiology
The developing of questions of Outer Space has only been greatly enhanced by the increase of technology and greater involvement by states, private actors and people seeking to use space above the typical uses i.e., satellites. Such an approach has carried on the original views of space delivered by the Apollo programme, which has inspired entrepreneurs, scientists, politicians, and lawyers to challenge and develop hypothetical opinions and business strategy. Nevertheless, outer space is a free for all without jurisdiction. This thesis will consider both the future of space governance and the Committee on Space Research (COSPAR) planetary protection policy.
The uptake of scientific missions through the solar system has formed an enhanced interest as more than ever space exploration is pushing the boundaries are political and legal certainty. The Outer Space Treaty presents a number of fundamental and core elements within space and promotes cooperation through the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS). As such the future of space governance will be considered as to whether the current practice is “fit for purpose”, or whether a new governance regime should be considered for the benefit of space cooperation. Moreover, appropriate discussions around the understanding of astrobiology and how such a road map sets out the need for a planetary protection resource during exploration of space will be examined in detail. COSPARs planetary protection policy will be examined in order to be able to justify whether there is any legal basis for such an implementation or whether the policy remains a recommendation
Lipid elongation and its role in prostate cancer
Prostate cancer is the most commonly diagnosed cancer in Australian men, and advanced stage disease is currently incurable. Prostate cancer development and progression is driven by androgens, male hormones such as testosterone, that control a suite of cellular processes via androgen receptor (AR) signalling. An important target of AR signalling in prostate cancer cells is lipid metabolism, as it is commonly dysregulated in cancer. Fatty acids are the building blocks of complex lipids within the cell (the lipidome), and fatty acid synthesis is one aspect of lipid metabolism controlled by AR signalling in prostate cancer. Recently, lipidomic analysis of prostate cancer cells stimulated by androgens demonstrated an increased abundance of long-chain phospholipid species compared to untreated control cells. This effect was found to be mediated by the elongation of very long chain fatty acid 5 (ELOVL5) enzyme. Knockdown of ELOVL5 reduced prostate cancer cell viability, suggesting that ELOVL5-mediated fatty acid elongation was important for prostate cancer cell homeostasis, however, the mechanisms to explain the effects of ELOVL5 were undefined. Therefore, this thesis aimed to determine the contribution of ELOVL5 and the production of long-chain fatty acids to prostate cancer cell phenotypes (Chapters 3 and 4), and analyse the accumulation of metabolic precursors and associated metabolic dysfunction following ELOVL5 targeting (Chapter 5). In Chapter 3, ELOVL5 protein levels were found to be positively correlated with mitochondrial respiration and inversely correlated with the levels of reactive oxygen species (ROS). Interestingly, only the monounsaturated fatty acid (MUFA) product of ELOVL5, cis-vaccenic acid (cVA) could rescue the effects of ELOVL5 knockdown on prostate cancer cell viability. Further investigation of cVA, in Chapter 4, demonstrated that cVA supplementation could increase prostate cancer cell viability and consistently rescue the effects of inhibition of the canonical MUFA-producing enzyme stearoyl-CoA desaturase 1 (SCD1), required for cVA production. Mechanistically, cVA was found to be incorporated into cardiolipins, a mitochondrial specific phospholipid, where it regulated mitochondrial-specific ROS production. Taken together, these findings from Chapters 3 and 4 identified the MUFA product of ELOVL5, cVA, as a novel oncogenic factor in prostate cancer. Finally, Chapter 5 considered the effects of targeting fatty acid elongation on malonyl-CoA accumulation. Malonyl-CoA is required for fatty acid elongation, and can reduce mitochondrial fatty acid oxidation (β-oxidation) through inhibition of carnitine palmitoyltransferase 1 (CPT1). Accordingly, ELOVL5 knockdown caused an accumulation of malonyl-CoA in prostate cancer cell lines, and reduced mitochondrial β-oxidation, identifying a previously unappreciated role for fatty acid elongation in the regulation of malonyl-CoA levels. Overall, this thesis demonstrates that ELOVL5 is a critical oncogenic factor in prostate cancer that promotes cell growth and proliferation through the production of the MUFA, cVA, and regulation of key substrate malonyl-CoA, that influence mitochondrial homeostasis and β-oxidation, respectively. These findings provide novel insight into the role of fatty acid elongation in prostate cancer, and highlight a potential therapeutic vulnerability of these cells that warrants further investigation.Thesis (Ph.D.) -- University of Adelaide, Adelaide Medical School, 202
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Space Debris: A Basis for Actively Removing Objects Under an International Legal Order
With over 500,000 objects in orbit, space pollution has now become a scientific, legal, and ethical issue and raises concerns on what the international community can do through existing ‘hard law’ and the development of ‘soft law’ to help tackle the problem. The purpose of this paper is to examine whether the application of the evolutionary principle of treaty interpretation to the Outer Space Treaty, enables for active removal of space debris in a manner consistent with space governance and which is acceptable to private corporations and States. Active Debris Removal (ADR) has only been used in specific circumstances which successfully removed an object. International law has hindered the process of mass removal of space debris, as objects cannot be removed without the consent of the relevant state. Therefore, this paper will consider whether customary international law and current state practice in analogous areas of international law, would allow or could develop to enable, the removal of an object from space without the need for consent of the launching state. Such an application will form a rigorous approach and introduction of space governance through an international multinational space agency approach for mutual agreement and cooperation without the need for an international treaty or political declaration. Such a principle, although not a new concept in areas such as international environmental law, would be new for international space law. However, as new and innovative activities are planned under the umbrella of the Outer Space Treaty, and by extension, general international law, it is wise to take a new and innovative approach to space law. Moreover, this paper aims at using maritime, environmental and international rules of responsibility to argue that the removal of objects in outer space does not need consent. This will be backed by an evolutionary approach to the interpretation of the Outer Space Treaty. This paper will make a unique and forward-looking legal and governance argument that will test not only the use of international law but also science, technology and political will
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