Phenotype correlations among the asymmetry measures.

<p>The correlation estimate is shown in the upper right triangle of the matrix and the p-value based on permutation testing is shown in the lower left triangle of the matrix.</p

Deformation phenotypes.

<p>During the affine registration process, native space images are skewed (sheared) to ‘correct’ hemispheric asymmetry and align the images to the symmetric template. The magnitude of the skewing is a quantitative measure of hemispheric asymmetry. The arrows in each panel indicate the direction volume is shifted during image registration. The asymmetric distribution of volume in the native space (non-deformed) image is therefore opposite to the direction of the arrows. The skews have been exaggerated to emphasize the otherwise subtle distortions introduced by the registration process. Panel A: A positive skew in the transverse plane corresponds to an anterior shift of voxels in the left hemisphere and a posterior shift of voxels in the right hemisphere during registration to the symmetric template. Panel B: A positive skew in the coronal plane leads to a ventral shift of voxels in the left hemisphere and a dorsal shift of voxels in the right hemisphere during registration to the symmetric template. Panel C shows the distributions of the normalized phenotypes.</p

Cerebral Widths and Asymmetry Quotient Distributions.

<p>Left panel shows an example of a traverse slice dorsal to the corpus callosum with cerebral widths indicated on the right hemisphere. Right panel shows the distributions of the asymmetry quotients for hemisphere volume and each cerebral width.</p

Cingulate sulcus asymmetry.

<p>Transverse Slices showing the relative position of the left and right ascending ramus of the cingulate sulcus. The left panel shows an image that was consistently scored as +2, the middle panel shows an image scored as symmetric (score = 0), and the right panel shows an image scored as −2.</p

Genetic (<b>ρ_G</b>) and environmental (<b>ρ_E</b>) correlations for cerebral width phenotypes.

<p>The estimate of the proportion of common genetic sources contributing to the phenotypic covariance of each pair of cerebral width is shown in the upper triangle of the table and the proportion of common environmental sources contributing to the covariance between traits is shown in the lower triangle of the table. The standard error of the estimate is in parentheses.</p

Average scores for cingulate sulcus asymmetry by sex and range.

<p>Average scores for cingulate sulcus asymmetry by sex and range.</p

Correlation coefficients of cerebral widths for each pair of regions.

<p>The Pearson's correlation is shown in the upper right triangle of the matrix and the p-value determined from permutation testing is shown in the lower left triangle of the matrix.</p