Distributions of age at acute infection, for PWID and non-PWID.

<p>Distributions of age at acute infection, for PWID and non-PWID.</p

Projected HCV-related disease burden in DALYs/year, over the period 1960–2039.

<p>Three historical incidence scenarios are compared (1-B, 2-B, and 3-B), with current treatment uptake and SVR rates assumed to apply to the year 2014 onwards.</p

Patterns of acute incidence underlying Scenarios 1 to 3.

<p>The assumed historical HCV incidence time series for Scenarios 1 to 3 are shown separately for PWID and non-PWID risk groups (upper, centre, and lower panels, respectively).</p

Progression probabilities for transitions between disease progression model states, and corresponding prior distributions.

<p>Background mortality probabilities were derived from the national age-specific mortality rates for Malaysia, adjusted for the degree of excess non-liver-related mortality calculated from persons diagnosed HCV Ab+ in Scotland (1991–2005), in which the window of 6 months subsequent to HCV diagnosis date is excluded from follow-up time to reduce bias associated with testing individuals presenting with disease.</p><p>Progression probabilities for transitions between disease progression model states, and corresponding prior distributions.</p

Projections of HCV-related disease outcomes for Scenario 1-B, over the period 1960–2039.

<p>Projected incidence and prevalence are shown in the upper and lower panels, respectively.</p

Average annual disease burden in the Netherlands in 2007–2011 for new cases of sexually-transmitted infections.

<p>YLD and YLL components are shown separately. Red lines indicate 95% uncertainty intervals.(DALY = Disability-Adjusted Life Year, YLD = Years Lived with Disability, YLL = Years of Life Lost).</p

Average annual disease burden in the Netherlands in 2007–2011 for new cases of respiratory diseases.

<p>YLD and YLL components are shown separately. Red lines indicate 95% uncertainty intervals. (DALY = Disability-Adjusted Life Year, YLD = Years Lived with Disability, YLL = Years of Life Lost).</p

Ranking of food-related diseases by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases (200 cases were added to each bubble for visibility reasons). Both axes are on a logarithmic scale. (DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p

Ranking of respiratory diseases by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases. Both axes are on a logarithmic scale. (DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p

Ranking of sexually-transmitted infections by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases. Both axes are on a logarithmic scale.(DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p