Does cognitive inflexibility predict violent extremist behaviour intentions? A registered direct replication report of Zmigrod et al., 2019

Purpose: Zmigrod et al. (2019a, Frontiers in Psychology, 10, 989) demonstrated that lower levels of cognitive flexibility predict a higher willingness to fight and die for the national in-group. We conducted a registered direct replication of their Study 1. Extending the original study, we examined whether the documented relationship held when a self-report measure for cognitive flexibility was introduced and when identity fusion was controlled for. We also investigated whether cognitive inflexibility predicts normative pro-group behaviour intentions. // Methods: Participants (N = 1378) reported in a cross-sectional survey study their willingness to fight, die and sacrifice themselves for the in-group and completed the Remote Associates (RAT) as and Wisconsin Card Sorting (WCST) tests. Afterwards, self-reported cognitive flexibility, identity fusion and normative pro-group behaviour intentions were assessed. // Results: Results showed a small negative relationship between RAT accuracy rates and willingness to fight and die. WCST accuracy rates were positively related with willingness to die but not correlated with willingness to fight. Self-report measures of cognitive flexibility were partially positively and partially negatively associated with support for violent extremism. There was further evidence that lower cognitive flexibility predicts higher normative pro-group behaviour intentions. A mini meta-analysis, which synthesized findings from the original study and our replication, demonstrated a relatively small negative correlation between cognitive flexibility and support for violent extremism. // Conclusions: In summary, even though not all individual results could be replicated, we confirmed the overall conclusion of the original study: lower cognitive flexibility predicted stronger willingness to fight and die for an in-group. The findings highlight that it is important to integrate cognitive style in multi-level frameworks of risk factors of violent extremism. Additionally, our results point out that the validity of different measures of cognitive flexibility, including self-report tools, must be further examined. Future research that evaluates cognitive flexibility training in the context of CVE/PVE interventions is also encouraged

The Base Rate Study: Developing Base Rates for Risk Factors and Indicators for Engagement in Violent Extremism

Improvements have been made in identifying the prevalence of risk factors/indicators for violent extremism. A consistent problem is the lack of base rates. How to develop base rates is of equal concern. This study has two aims: (i) compare two methods for developing base rates; the Unmatched Count Technique (UCT) and direct questioning, (ii) generate base rates in a general population sample and compare these to a sample of lone‐actor terrorists (n = 125). We surveyed 2108 subjects from the general population. Participants were recruited from an online access panel and randomly assigned to one of three conditions; direct survey, control, or UCT. Survey items were based on a lone‐actor terrorist codebook developed from the wider literature. Direct questioning was more suitable under our study conditions where UCT resulted in deflation effects. Comparing the base rates identified a number of significant differences: (i) lone‐actor terrorists demonstrated propensity indicators related to a cognitive susceptibility, and a crime‐ and/or violence‐supportive morality more often; the general sample demonstrated protective factors more often, (ii) lone‐actor terrorists demonstrated situational indicators related to a crime‐ and/or violence‐supportive morality more often, whereas the general sample experienced situational stressors more often, (iii) lone‐actor terrorists demonstrated indicators related to exposure to extremism more often. Results suggest there are measurable differences in the prevalence of risk factors between lone‐actor terrorists and the general population. However, no single factor “predicts” violent extremism. This bears implications for our understanding of the interrelation of risk and protective factors, and for the risk assessment of violent extremism

Gold Mining in the Peruvian Amazon: Global Prices, Deforestation, and Mercury Imports

Many factors such as poverty, ineffective institutions and environmental regulations may prevent developing countries from managing how natural resources are extracted to meet a strong market demand. Extraction for some resources has reached such proportions that evidence is measurable from space. We present recent evidence of the global demand for a single commodity and the ecosystem destruction resulting from commodity extraction, recorded by satellites for one of the most biodiverse areas of the world. We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of increase in international gold price (∼18%/yr). We detect that the new pattern of mining deforestation (1915 ha/year, 2006–2009) is outpacing that of nearby settlement deforestation. We show that gold price is linked with exponential increases in Peruvian national mercury imports over time (R2 = 0.93, p = 0.04, 2003–2009). Given the past rates of increase we predict that mercury imports may more than double for 2011 (∼500 t/year). Virtually all of Peru's mercury imports are used in artisanal gold mining. Much of the mining increase is unregulated/artisanal in nature, lacking environmental impact analysis or miner education. As a result, large quantities of mercury are being released into the atmosphere, sediments and waterways. Other developing countries endowed with gold deposits are likely experiencing similar environmental destruction in response to recent record high gold prices. The increasing availability of satellite imagery ought to evoke further studies linking economic variables with land use and cover changes on the ground

Operant Sensation Seeking Requires Metabotropic Glutamate Receptor 5 (mGluR5)

Pharmacological and genetic studies have suggested that the metabotropic glutamate receptor 5 (mGluR5) is critically involved in mediating the reinforcing effects of drugs of abuse, but not food. The purpose of this study was to use mGluR5 knockout (KO), heterozygous (Het), and wildtype (WT) mice to determine if mGluR5 modulates operant sensation seeking (OSS), an operant task that uses varied sensory stimuli as a reinforcer. We found that mGluR5 KO mice had significantly reduced OSS responding relative to WT mice, while Het mice displayed a paradoxical increase in OSS responding. Neither KO nor Het mice exhibited altered operant responding for food as a reinforcer. Further, we assessed mGluR5 KO, Het and WT mice across a battery of cocaine locomotor, place preference and anxiety related tests. Although KO mice showed expected differences in some locomotor and anxiety measures, Het mice either exhibited no phenotype or an intermediate one. In total, these data demonstrate a key role for mGluR5 in OSS, indicating an important role for this receptor in reinforcement-based behavior

Tumor Necrosis Factor α Inhibits Expression of the Iron Regulating Hormone Hepcidin in Murine Models of Innate Colitis

Background: Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control hepcidin expression during states of intestinal inflammation, we sought to shed light on this issue using mouse models. Methodology/Principal Findings: Hepcidin expression was evaluated in two types of intestinal inflammation caused by innate immune activation—dextran sulfate sodium (DSS)-induced colitis in wild-type mice and the spontaneous colitis occurring in T-bet/Rag2-deficient (TRUC) mice. The role of tumor necrosis factor (TNF) $\alpha$ was investigated by in vivo neutralization, and by treatment of a hepatocyte cell line, as well as mice, with the recombinant cytokine. Expression and activation of Smad1, a positive regulator of hepcidin transcription, were assessed during colitis and following administration or neutralization of TNF$\alpha$. Hepcidin expression progressively decreased with time during DSS colitis, correlating with changes in systemic iron distribution. TNF$\alpha$ inhibited hepcidin expression in cultured hepatocytes and non-colitic mice, while TNF$\alpha$ neutralization during DSS colitis increased it. Similar results were obtained in TRUC mice. These effects involved a TNF$\alpha$-dependent decrease in Smad1 protein but not mRNA. Conclusions/Significance: TNF$\alpha$ inhibits hepcidin expression in two distinct types of innate colitis, with down-regulation of Smad1 protein playing an important role in this process. This inhibitory effect of TNF$\alpha$ may be superseded by other factors in the context of T cell-mediated colitis given that in the latter form of intestinal inflammation hepcidin is usually up-regulated

Stable Genetic Effects on Symptoms of Alcohol Abuse and Dependence from Adolescence into Early Adulthood

Relatively little is known about how genetic influences on alcohol abuse and dependence (AAD) change with age. We examined the change in influence of genetic and environmental factors which explain symptoms of AAD from adolescence into early adulthood. Symptoms of AAD were assessed using the four AAD screening questions of the CAGE inventory. Data were obtained up to six times by self-report questionnaires for 8,398 twins from the Netherlands Twin Register aged between 15 and 32 years. Longitudinal genetic simplex modeling was performed with Mx. Results showed that shared environmental influences were present for age 15–17 (57%) and age 18–20 (18%). Unique environmental influences gained importance over time, contributing 15% of the variance at age 15–17 and 48% at age 30–32. At younger ages, unique environmental influences were largely age-specific, while at later ages, age-specific influences became less important. Genetic influences on AAD symptoms over age could be accounted for by one factor, with the relative influence of this factor differing across ages. Genetic influences increased from 28% at age 15–17 to 58% at age 21–23 and remained high in magnitude thereafter. These results are in line with a developmentally stable hypothesis that predicts that a single set of genetic risk factors acts on symptoms of AAD from adolescence into young adulthood

Does cognitive inflexibility predict violent extremist behaviour intentions? A registered direct replication report of Zmigrod, Rentfrow, & Robbins, 2019

PURPOSE: Research assessing violent extremist risk factors thus far largely ignored the role of cognitive processes. Zmigrod and colleagues (2019a) addressed this gap and presented first systematic evidence that lower levels of cognitive flexibility predict a higher willingness to fight and, ultimately, die for a national ingroup. This finding has important theoretical and practical implications. In order to strengthen the potential contribution of Zmigrod et al.’s work, we will conduct a registered direct replication of Study 1. Extending the original study, we further examine whether the documented relationship still holds when a self‐report measure for cognitive flexibility is introduced and when analyses control for identity fusion. We also investigate if cognitive inflexibility solely predicts violent or also normative pro‐group behaviour intentions. METHODS: Following Zmigrod, Rentfrow, and Robbins (2019a), we will administer a cross‐sectional survey study. Participants (N = 1,378) report their willingness to fight, die, and sacrifice themselves for the ingroup and complete the Remote Associates as well as Wisconsin Card Sorting tests. Afterwards, additional measures of self‐reported cognitive flexibility, identity fusion, and normative pro‐group behaviour are assessed. RESULTS: To be completed. CONCLUSIONS: To be completed