Boosting the performance of remote GPU virtualization using InfiniBand Connect-IB and PCIe 3.0

© 2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.[EN] A clear trend has emerged involving the acceleration of scientific applications by using GPUs. However, the capabilities of these devices are still generally underutilized. Remote GPU virtualization techniques can help increase GPU utilization rates, while reducing acquisition and maintenance costs. The overhead of using a remote GPU instead of a local one is introduced mainly by the difference in performance between the internode network and the intranode PCIe link. In this paper we show how using the new InfiniBand Connect-IB network adapters (attaining similar throughput to that of the most recently emerged GPUs) boosts the performance of remote GPU virtualization, reducing the overhead to a mere 0.19% in the application tested.This work was funded by the Generalitat Valenciana under Grant PROMETEOII/2013/009 of the PROMETEO program phase II. This material is based upon work supported by the U. S. Department of Energy, Office of Science, Advanced Scientific Computing Research (SC-21), under Contract No. DE-AC02-06CH11357. Authors from the Universitat Politècnica de València and Universitat Jaume I are grateful for the generous support provided by Mellanox Technologies.Reaño González, C.; Silla Jiménez, F.; Peña Monferrer, AJ.; Shainer, G.; Schultz, S.; Castelló Gimeno, A.; Quintana Orti, ES.... (2014). Boosting the performance of remote GPU virtualization using InfiniBand Connect-IB and PCIe 3.0. En 2014 IEEE International Conference on Cluster Computing (CLUSTER). IEEE. 266-267. doi:10.1109/CLUSTER.2014.6968737S26626

Non-linear I(V)I(V) Characteristics of Luttinger Liquids and Gated Hall Bars

Non-linear current voltage characteristics of a disordered Luttinger liquid are calculated using a perturbative formalism. One finds non-universal power law characteristics of the form $I(V)\sim V^{1/(2\tilde{g}-1)}$ which is valid both in the superfluid phase when $I$ is small and also in the insulator phase when $I$ is large. Mesoscopic voltage fluctuations are also calculated. One finds \Var(\Delta V) \sim I^{4\tilde{g}-3}. Both the $I(V)$ characteristic and the voltage fluctuations exhibit universal power law behavior at the superfluid insulator transition where \tilde{g}=\tot. The possible application of these results to the non-linear transport properties of gated Hall bars is discussed.Comment: 8 pages. 4 uuencoded tiff figures available upon request to [email protected]

Prospective randomized study comparing the Teleflex Medical SaphLITE Retractor to the Ethicon CardioVations Clearglide Endoscopic System

BACKGROUND: Several minimally invasive saphenous vein harvesting techniques have been developed to reduce morbidities associated with coronary artery bypass grafting. This prospective, randomized study was designed to compare two commonly used minimally invasive saphenous vein harvesting techniques, the SaphLITE Retractor System (Teleflex Medical) and the Clearglide Endoscopic Vessel Harvesting System (Ethicon CardioVations, Inc.). METHODS: Between January 2003 and March 2004, a total of 200 patients scheduled for primary, nonemergent coronary artery bypass grafting, with or without concomitant procedures were randomized into two groups: SaphLITE (n = 100) and Clearglide (n = 100). Pre-, intra- and postoperative data was collected and subjected to statistical analysis. Randomization provided homogenous groups with respect to preoperative risk factors. RESULTS: Harvest location for the SaphLITE group was thigh (n = 40), lower leg (n = 5) and both lower leg and thigh (n = 55). The location of harvest for the Clearglide group was thigh (n = 3), lower leg (n = 16) and both lower leg and thigh (n = 81). The mean incision length was 3.6 cm (range, 2–6) in the SaphLITE group versus 2.1 cm (range, 1–4) in the Clearglide group (p < 0.05). The total incision length was 12.9 cm versus 8.9 (p < 0.05) in the SaphLITE and Clearglide groups. Conversion to the open technique occurred in 5 SaphLITE patients and 7 Clearglide patients. Intraoperative leg exploration for bleeding occurred in two of the Clearglide patients and none of the SaphLITE patients. Post-operative complications specifically related to minimally invasive harvesting technique, including a two-week post-discharge visit, were not statistically different between the groups. CONCLUSION: The saphenous vein can be safely harvested utilizing the SaphLITE and Clearglide systems. While the Clearglide system allows for fewer incisions (number and length) and less harvest time, these benefits may be outweighed by the increased cost of the Clearglide system compared to the SaphLITE retractor

Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately in the interventional suite is appealing to all operators. The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF). This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models. In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging. LVOT-AR > 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation. The LVOT-AR differentiates the individual performances of many old and novel devices and is being used in ongoing randomized trials and registries

Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately in the interventional suite is appealing to all operators. The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF). This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models. In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging. LVOT-AR &gt; 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation. The LVOT-AR differentiates the individual performances of many old and novel devices and is being used in ongoing randomized trials and registries

Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin

Recent genomic analyses of pathologically-defined tumor types identify “within-a-tissue” disease subtypes. However, the extent to which genomic signatures are shared across tissues is still unclear. We performed an integrative analysis using five genome-wide platforms and one proteomic platform on 3,527 specimens from 12 cancer types, revealing a unified classification into 11 major subtypes. Five subtypes were nearly identical to their tissue-of-origin counterparts, but several distinct cancer types were found to converge into common subtypes. Lung squamous, head & neck, and a subset of bladder cancers coalesced into one subtype typified by TP53 alterations, TP63 amplifications, and high expression of immune and proliferation pathway genes. Of note, bladder cancers split into three pan-cancer subtypes. The multi-platform classification, while correlated with tissue-of-origin, provides independent information for predicting clinical outcomes. All datasets are available for data-mining from a unified resource to support further biological discoveries and insights into novel therapeutic strategies