24 research outputs found
Surgical management and outcome of meningiomas with tentorial involvement - our institutional experience
Meningioma surgery in the elderly: clinical radiological grading system (CRGS), SKALE score (Sex, Karnofsky, ASA, Location, Edema) and outcome - a multivariate analysis
Iatrogenic tension pneumothorax developed during ventriculo-peritoneal shunt surgery and detected shortly before extubation
Hemodynamic stress, inflammation and intracranial aneurysms development and rupture: a systematic review.
Background: There seems to be a pathogenetic link between hemodynamics and inflammatory arterial wall alteration leading to the development and rupture of intracranial aneurysms (IAs). Noninvasive assessment of the inflammatory status of the aneurysm wall may guide the management of unruptured IAs by identifying reliable markers for increased rupture risk. Methods: We conducted a qualitative systematic review following the ENTREQ (Enhancing Transparency in Reporting the Synthesis of Qualitative Research) framework. A search was made in MEDLINE/PubMed, Embase, and CINAHL from database inception to October 2017 using the terms “intracranial aneurysm” and “cerebral aneurysm” linked with the following key words: inflammation, hemodynamic(s), remodeling, macrophages, neutrophils, lymphocytes, complement system, vascular smooth muscle cells, mast cells, cytokines, and inflammatory biomarkers. Results: One hundred and twenty-three articles were included in the review. Conclusions: In this systematic review, we explore the relationship between hemodynamic stress, inflammation, vascular remodeling, and the formation and rupture of IAs to develop novel strategies to predict the individual risk of aneurysmal rupture