Heralded generation of a micro-macro entangled state

Using different optical setups based on squeezed state and photon subtraction we show how optical entanglement between a macroscopic and a microscopic state - the so-called Schrodinger cat state or micro-macro state - can be generated. The entangled state is heralded and is thus produced a priori in contrast to previous proposals. We define the macroscopicity of the macroscopic part of the state as their mean distance in phase space and the success rate in discriminating them with homodyne detection, and subsequently, based on these measures we investigate the macroscopicity of different states. Furthermore, we show that the state can be used to map a microscopic qubit onto a macroscopic one thereby linking a qubit processor with a qumode processor

Increasing the photon collection rate from a single NV center with a silver mirror

In the pursuit of realizing quantum optical networks, a large variety of different approaches have been studied to achieve a single photon source on-demand. The common goal for these approaches is to harvest all the emission from a quantum emitter into a single spatial optical mode while maintaining a high signal-to-noise ratio. In this work, we use a single nitrogen vacancy center in diamond as a quantum emitter operating at ambient conditions and we demonstrate an increased photon count rate up to a factor of 1.76 by placing a silver mirror fabricated on the end facet of an optical fiber near the emitter

Ethics in extracorporeal life support:a narrative review

Abstract During 50 years of extracorporeal life support (ECLS), this highly invasive technology has left a considerable imprint on modern medicine, and it still confronts researchers, clinicians and policymakers with multifarious ethical challenges. After half a century of academic discussion about the ethics of ECLS, it seems appropriate to review the state of the argument and the trends in it. Through a comprehensive literature search on PubMed, we identified three ethical discourses: (1) trials and evidence accompanying the use of ECLS, (2) ECLS allocation, decision-making and limiting care, and (3) death on ECLS and ECLS in organ donation. All included articles were carefully reviewed, arguments extracted and grouped into the three discourses. This article provides a narrative synthesis of these arguments, evaluates the opportunities for mediation and substantiates the necessity of a shared decision-making approach at the limits of medical care

Optimising Bacterial DNA Extraction from Faecal Samples: Comparison of Three Methods

Culture independent methods are used widely in diagnostic laboratories for infectious disease Isolation of genomic DNA from clinical samples is the first and important step in the procedure. Several procedures for extracting DNA from faecal samples have been described, including different mechanical cell disruptors. To our knowledge, the use of TissueLyser as a mechanical disruptor on faecal samples before DNA extraction has not been previously described. The purpose of the study was to implement a method for preparing faecal samples for optimal DNA extraction. Thus, three different procedures for extracting DNA from human faeces were compared. This was done either by using the mechanical disrupter by Mini BeadBeater 8, or the TissueLyser both followed by DNA purification using QIAamp DNA stool MiniKit, in comparison with DNA extractions using QIAamp DNA stool MiniKit without any prior mechanical disruption, according to manufacturer’s instructions. The obtained DNA from the three procedures was analysed by DGGE, and the number of bands was compared between each procedure. There was no significant difference between the numbers of bacterial bands obtained from DGGE when using a TissueLyser or Mini BeadBeater 8, so the two different mechanical cell disruptors can be used comparably when isolating bacterial DNA from faecal samples. The QIAamp DNA stool MiniKit alone resulted in a reduced number of bands compared to the two mechanical disruption methods

Maternal Recreational Exercise during Pregnancy in relation to Children's BMI at 7 Years of Age

Exposures during fetal life may have long-term health consequences including risk of childhood overweight. We investigated the associations between maternal recreational exercise during early and late pregnancy and the children's body mass index (BMI) and risk of overweight at 7 years. Data on 40,280 mother-child pairs from the Danish National Birth Cohort was used. Self-reported information about exercise was obtained from telephone interviews around gestational weeks 16 and 30. Children's weight and height were reported in a 7-year follow-up and used to calculate BMI and overweight status. Data was analyzed using multiple linear and logistic regression models. Recreational exercise across pregnancy was inversely related to children's BMI and risk of overweight, but all associations were mainly explained by smoking habits, socioeconomic status, and maternal pre-pregnancy BMI. Additionally, we did not find exercise intensity or changes in exercise habits in pregnancy related to the children's BMI or risk of overweight