1,419 research outputs found

    Qualitative Efficiency Assessment of Markets: An Institutional Approach to Training

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    We investigate the effect of institutions on efficiency of training markets. After setting up a theoretical institutional framework that shows how institutions affect efficiency, we apply this framework to the real world. An empirical analysis of institutions affecting training markets will enable us to determine the institutional efficiency of these markets, under the assumption that a positive relationship exists between efficiency and productivity. Finally, we compare institutional efficiency scores of national training markets to other measures of productivity and ask whether a particular set of institutions maximises efficiency.institutions, vocational training, continuing education, labour markets, productivity, efficiency, production frontier

    Human Capital and Labour Productivity, Integration of Institutions and Endogenous Growth

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    This paper is part of a project that attempts to reveal the way labour market institutions, human capital and labour productivity are interconnected. First we discuss two approaches in the human capital theory, stressing some difficulties that could be solved if the approaches are combined. It is argued that the Nelson-Phelps approach could be improved by adding elements from the Lucas model. We think that the production factor of human capital needs a more detailed description than usual in empirical research, e.g. further schooling and training, experience and external effects. Empirical tests show that the frequently obtained conclusion that investments in higher education are too low are doubtful. The tests also show the importance of further education and training, especially on-the-job training.human capital, labour productivity, specificity, turnover, labour markets, education, off-the-job training, on-the-job training, models, experience, learning by doing

    Cholesterol, bile acid and triglyceride metabolism intertwined

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    Cholesterol, bile acid and triglyceride metabolism intertwined

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    Integration process factors and effects

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    It is assumed in Merger & Acquisitions (M&A) research that there exists a relationship between business and IS aspects. However, research and literature explicitly addressing the relationship between both is scarce. In this paper we introduce a model to understand the aspects that play a role in an integration process. We focus on process factors and effects, both from the business and IS domain, in particular we are focusing on their interaction. Two cases in the transport industry are presented and discussed. The research discusses the validity of recurring integration process factors and effects, but also indicates the relevance of contextual aspects. The research contributes both to M&A research as well as to IS research by increasing the understanding of factors that impact integration processes and by that it gives direction how these factors should be managed

    Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats

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    An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal permeability in rats. However, it is unknown how and where in the gastrointestinal tract Ca and scFOS exert their effects. Rats were fed a Western low-Ca control diet, or a similar diet supplemented with either Ca or scFOS. Lactulose plus mannitol and Cr-EDTA were added to the diets to quantify small and total gastrointestinal permeability, respectively. Additionally, colonic tissue was mounted in Ussing chambers and exposed to faecal water of these rats. Dietary Ca immediately decreased urinary Cr-EDTA excretion by 24 % in Ca-fed rats compared with control rats. Dietary scFOS increased total Cr-EDTA permeability gradually with time, likely reflecting relatively slow gut microbiota adaptations, which finally resulted in a 30 % increase. The lactulose: mannitol ratio was 15 % higher for Ca-fed rats and 16 % lower for scFOS-fed rats compared with control rats. However, no dietary effect was present on individual urinary lactulose and mannitol excretion. The faecal waters did not influence colonic permeability in Ussing chambers. In conclusion, despite effects on the lactulose: mannitol ratio, individual lactulose values did not alter, indicating that diet did not influence small-intestinal permeability. Therefore, both nutrients affect permeability only in the colon: Ca decreases, while scFOS increase colonic permeability. As faecal water did not influence permeability in Ussing chambers, probably modulation of mucins and/or microbiota is important for the in vivo effects of dietary Ca and scFOS

    An attempt to define the sodium requirements of lactating dairy cows in a tropical environment

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    BACKGROUND: Lactating dairy cattle in the tropics may require more sodium (Na) owing to the hot and humid climatic conditions. It is unknown whether the current recommendations on Na for lactating cows can be quantitatively used in tropical countries. This study attempted to define the Na requirement of lactating dairy cows under tropical conditions by measuring Na levels in saliva, milk and faeces. RESULTS: The concentrations of Na and potassium (K) in milk, faeces and serum were not affected by dietary treatments. The amount of Na absorbed by cows fed the basal (low-Na) diet containing 0.4 g Na kg-1 dry matter (DM) was equal to the amount of Na lost in the milk, showing that these animals were fed an Na-deficient ration. This observation was corroborated by salivary Na and K levels, with the cows on the low-Na diet having salivary Na concentrations below 120 mmol L-1 in combination with salivary K concentrations above 20 mmol L-1 (P <0.05). CONCLUSION: Consumption of a daily ration formulated to contain the current Na requirement set by the NRC appears to provide too much Na for lactating cows under tropical conditions. A tentative value of 1.2 g kg-1 DM is proposed as the Na requirement for dairy cows under tropical conditions. Copyright © 2011 Society of Chemical Industr

    Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments

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    Translating neuronal activity to measurable behavioral changes has been a long-standing goal of systems neuroscience. Recently, we have developed a model of phase-reversal learning of the vestibulo-ocular reflex, a well-established, cerebellar-dependent task. The model, comprising both the cerebellar cortex and vestibular nuclei, reproduces behavioral data and accounts for the changes in neural activity during learning in wild type mice. Here, we used our model to predict Purkinje cell spiking as well as behavior before and after learning of five different lines of mutant mice with distinct cell-specific alterations of the cerebellar cortical circuitry. We tested these predictions by obtaining electrophysiological data depicting changes in neuronal spiking. We show that our data is largely consistent with the model predictions for simple spike modulation of Purkinje cells and concomitant behavioral learning in four of the mutants. In addition, our model accurately predicts a shift in simple spike activity in a mutant mouse with a brainstem specific mutation. This combination of electrophysiological and computational techniques opens a possibility of predicting behavioral impairments from neural activity
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