Escapement of the Cape rock lobster (Jasus lalandii ) through the mesh and entrance of commercial traps

Metal-framed traps covered with polyethylene mesh used in the fishery for the South African Cape rock lobster (Jasus lalandii) incidentally capture large numbers of undersize (<75 mm CL) specimens. Air-exposure, handling, and release procedures affect captured rock lobsters and reduce the productivity of the stock, which is heavily fished. Optimally, traps should retain legalsize rock lobsters and allow sublegal animals to escape before traps are hauled. Escapement, based on lobster morphometric measurements, through meshes of 62 mm, 75 mm, and 100 mm was investigated theoretically under controlled conditions in an aquarium, and during field trials. SELECT models were used to model escapement, wherever appropriate. Size-selectivity curves based on the logistic model fitted the aquarium and field data better than asymmetrical Richards curves. The lobster length at 50% retention (L50) on the escapement curve for 100-mm mesh in the aquarium (75.5 mm CL) approximated the minimum legal size (75 mm CL); however estimates of L50 increased to 77.4 mm in field trials where trapentrances were sealed, and to 82.2 mm where trap-entrances were open. Therfore, rock lobsters that cannot escape through the mesh of sealed field traps do so through the trap entrance of open traps. By contrast, the wider selection range and lower L25 of field, compared to aquarium, trials (SR = 8.2 mm vs. 2.6 mm; L25 =73.4 mm vs. 74.1 mm), indicate that small lobsters that should be able to escape from 100-mm mesh traps do not always do so. Escapement from 62-mm mesh traps with open entrance funnels increased by 40−60% over sealed traps. The findings of this study with a known size distribution, are related to those of a recent indirect (comparative) study for the same species, and implications for trap surveys, commercial catch rates, and ghost fishing are discussed

Comparative response of blood cortisol levels to two different doses of intravenous acth (tetracosactrin) in overweight cats

Fifteen middle-aged to older, overweight cats were investigated to rule out hyperadrenocorticism as a cause of their weight problem, using two different protocols for the adrenocorticotrophic hormone (ACTH) stimulation test. The cats received intravenous synthetic ACTH (tetracosactrin) at a dose of 125 µg initially and then, between 2 and 3 weeks later, a second test was performed using a dose of 250 µg intravenously. The peak of the mean serum cortisol concentrations taken at all time points, occurred at 60 minutes following the 125 µg dose and at 120 minutes following the 250 µg dose. There was no statistically significant difference between the cortisol peaks attained using either dose of tetracosactrin. There was, however, a significantly higher serum cortisol concentration attained after the higher dose at the 180 minutes time point, indicating a more prolonged response, when compared with the lower dose. The mean basal cortisol concentration was 203 nmol/l (range 81 – 354 nmol/l). The cats were followed up for one year after the initial investigations. Urine obtained one year later in the cats’ home environment, showed a mean urinary cortisol/creatinine ratio (UCCR) of 3.3 x 10 -6 (range 0.85 - 8.67 x 10 -6). A mean weight loss of 6 per cent was achieved over the period of the study. The weight loss, lack of development of clinical signs and the normal UCCR’s confirm that none of these cats had gone on to develop hyperadrenocorticism.Dissertation (MMedVet (Med))--University of Pretoria, 2001.Companion Animal Clinical Studiesunrestricte

An optimised QPSK-based receiver structure for possibly sparse data transmission over narrowband and wideband communication systems

In this dissertation an in-depth study was conducted into the design, implementation and evaluation of a QPSK-based receiver structure for application in a UMTS WCDMA environment. The novelty of this work lies with the specific receiver architecture aimed to optimise the BER performance when possibly sparse data streams are transmitted. This scenario is a real possibility according to Verd´u et al [1] and Hagenauer et al [2–6]. A novel receiver structure was conceptualised, developed and evaluated in both narrowband and wideband scenarios, where it was found to outperform conventional receivers when a sparse data stream is transmitted. In order to reach the main conclusions of this study, it was necessary to develop a realistic simulation platform. The developed platform is capable of simulating a communication system meeting the physical layer requirements of the UMTS WCDMA standard. The platform can also perform narrowband simulations. A flexible channel emulator was developed that may be configured to simulate AWGN channel conditions, frequency non-selective fading (either Rayleigh or Rician with a configurable LOS component and Doppler spread), or a full multipath scenario where each path has a configurable LOS component, Doppler spread, path gain and path delay. It is therefore possible to even simulate a complex, yet realistic, COST207-TU channel model. The platform is also capable of simulating MUI. Each interfering user has a unique and independent multipath fading channel, while sharing the same bandwidth. Finally, the entire platform executes all simulations in baseband for improved simulation times. The research outputs of this work are summarised below: A parameter, the sparseness measure, was defined in order to quantify the level by which a data stream differs from an equiprobable data stream. A novel source model was proposed and developed to simulate data streams with a specified amount of sparseness. An introductory investigation was undertaken to determine the effect of simple FEC techniques on the sparseness of an encoded data stream. Novel receiver structures for both narrowband and wideband systems were proposed, developed and evaluated for systems where possibly sparse data streams may be transmitted. Analytic expressions were derived to take the effect of sparseness into account in communication systems, including expressions for the joint PDF of a BPSK branch, the optimal decision region of a detector in AWGN conditions as well as the BER performance of a communication system employing the proposed optimal receiver in both AWGN channel conditions as well as in flat fading channel conditions. Numerous BER performance curves were obtained comparing the proposed receiver structure with conventional receivers in a variety of channel conditions, including AWGN, frequency non-selective fading and a multipath COST207-TU channel environment, as well as the effect of MUI. AFRIKAANS : In hierdie verhandeling word ’n in-diepte studie gedoen rakende die ontwerp, implementasie en evaluasie van ’n KPSK-gebaseerde ontvanger struktuur wat in ’n UMTS WKVVT omgewing gebruik kan word. Die bydrae van hierdie werk lˆe in die spesifieke ontvanger argitektuur wat daarop mik om die BFT werksverrigting te optimeer wanneer yl data strome versend word. Hierdie is ’n realistiese moontlikheid volgens Verd´u et al [1] en Hagenauer et al [2–6]. ’n Nuwe ontvanger struktuur is gekonsepsualiseer, ontwikkel en evalueer vir beide noueband en wyeband stelsels, waar dit gevind is dat dit beter werksverrigting lewer as tradisionele ontvangers wanneer yl data strome versend word. Dit was nodig om ’n realistiese simulasie platform te ontwikkel om die belangrikste gevolgtrekkings van hierdie studie te kan maak. Die ontwikkelde platform is in staat om ’n kommunikasie stelsel te simuleer wat aan die fisiese laag vereistes van die UMTS WKVVT standaard voldoen. Die platform kan ook noueband stelsels simuleer. ’n Aanpasbare kanaal simulator is ontwikkel wat opgestel kan word om SWGR kanaal toestande, plat duining (beide Rayleigh of Ricies met ’n verstelbare siglyn komponent en Doppler verspreiding), sowel as ’n veelvuldige pad omgewing (waar elke unieke pad ’n verstelbare siglyn komponent, Doppler verspreiding, pad wins en pad vertraging het) te emuleer. Dit is selfs moontlik om ’n komplekse, maar steeds realistiese COST207-TU kanaal model te simuleer. Die platform het ook die vermo¨e om VGS te simuleer. Elke steurende gebruiker het ’n unieke en onafhanklike veelvuldige pad deinende kanaal, terwyl dieselfde bandwydte gedeel word. Laastens, alle simulasies van die platvorm word in basisband uitgevoer wat verkorte simulasie periodes verseker. Die navorsingsuitsette van hierdie werk kan as volg opgesom word: ’n Parameter, die ylheidsmaatstaf, is gedefin¨ýeer om dit moontlik te maak om die vlak waarmee die ylheid van ’n datastroom verskil van ’n ewekansige stroom te versyfer. ’n Nuwe bronmodel is voorgestel en ontwikkel om datastrome met ’n spesifieke ylheid te emuleer. ’n Inleidende ondersoek is onderneem om vas te stel wat die effek van VFK tegnieke op die ylheid van ’n enkodeerde datastroom is. Nuwe ontvanger strukture is voorgestel, ontwikkel en evalueer vir beide noueband en wyeband stelsels waar yl datastrome moontlik versend kan word. Analitiese uitdrukkings is afgelei om die effek van ylheid in ag te neem in kommunikasie stelsels. Uitdrukkings vir onder andere die gedeelte WDF van ’n BFVK tak, die optimale beslissingspunt van ’n detektor in SWGR toestande, sowel as die BFT werksverrigting van ’n kommunikasie stelsel wat van die voorgestelde optimale ontvangers gebruik maak, hetsy in SWGR of in plat duinende kanaal toestande. Talryke BFT werksverrigting krommes is verkry wat die voorgestelde ontvanger struktuur vergelyk met die konvensionele ontvangers in ’n verskeidenheid kanaal toestande, insluitend SWGR, plat duinende kanale en ’n veelvuldige pad COST207-TU kanaal omgewing, sowel as in die teenwoordigheid van VGS.</p CopyrightDissertation (MEng)--University of Pretoria, 2010.Electrical, Electronic and Computer Engineeringunrestricte

Medical management of myxomatous mitral valve disease : an evidence-based veterinary medicine approach

Myxomatous mitral valve disease (MMVD) is the most common heart disease of dogs. The current management of MMVD in dogs is mostly pharmacological, and the recommendations for treatment are based on a number of veterinary studies. Notwithstanding the current consensus regarding the medical management of MMVD, there remains active debate as to which drugs are the most effective. In order to understand how recommendations are constructed in the pharmacological management of diseases, the veterinarian needs to understand the concept of evidence-based veterinary medicine, and how the findings of these studies can be applied in their own practices. This review summarises the current veterinary literature and explains how the consensus regarding the management of MMVD has been reached. This review highlights the limitations of veterinary studies in order to provide veterinary practitioners with a sense of the difficulty there is in establishing the benefit of one treatment over the other. Veterinarians should therefore apply treatment recommendations based on the best evidence, integrated with a pathomechanistic understanding of the disease process and clinical experience.http://www.jsava.co.zaam201

Advances in the understanding of the pathogenesis, progression and diagnosis of myxomatous mitral valve disease in dogs

A number of key questions remain unanswered in the pathogenesis of myxomatous mitral valve disease (MMVD). As MMVD typically afflicts small-breed dogs, a genetic basis has been implied. In addition, the fact that not all dogs within a risk group develop MMVD is still unexplained. Research into the pathogenesis of MMVD typically falls under three categorical divisions, namely genetic factors, mechanical factors of the valve and systemic factors. Genetic studies have implicated certain loci in the pathogenesis of MMVD. Of particular interest is the insulin-like growth factor (IGF)-1 locus, as IGF-1 is also associated with growth. The mechanical structure and function of the mitral valve have also received much attention in recent years. What has emerged is the notion of a highly complex dynamic structure, which has an uneven distribution of stress and strain according to the flow of blood. Research efforts have also identified a number of systemic factors such as cytokines and signalling pathways that may contribute to the failure of the valve. Serotonin remains an area of interest in this field. Taken together, the amalgamation of research efforts in these three areas will go a long way towards resolving the understanding of this disease. Another area of focus in MMVD has been the development of clinical tests to diagnose the onset of congestive heart failure. To this end, echocardiographic indices and biochemical markers have been investigated. Echocardiographic indices such as left atrial to aortic ratio and the N-terminal of the prohormone brain natriuretic peptide (NT-proBNP) have been identified as specific risk factors to predict progression. Advanced imaging studies such as cardiac magnetic resonance imaging have enabled investigators to determine the earliest remodelling changes that occur in MMVD.http://www.jsava.co.zaam201

Early enteral nutrition in puppies with parvovirus enteritis

Canine parvovirus (CPV) enteritis is an important cause of severe, often fatal enteritis in dogs. Survival rates can be as high as 90% when puppies receive intensive treatment at tertiary veterinary facilities. No disease-specific therapies exist and treatment consists of supportive therapies. These therapies include intensive fluid therapy, antibiotic therapy, antiemetic therapy and analgesic therapy. Anthelminthic therapy is added to eliminate possible concurrent verminosis. One supportive measure which was found to be associated with more rapid clinical improvement in canine parvovirus enteritis is the early implementation of enteral nutrition. This article reviews the research findings in various aspects of early enteral nutrition in both human and animal critical care. Different naso-enteric feeding devices are compared and various feeding methods for the various clinical scenarios encountered with canine parvovirus enteritis are briefly discussed. The concept of gastric residual volume and its potential role in early enteral nutrition is evaluated. The authors’ view on how these research findings can be practically applied to treat puppies with canine parvovirus enteritis is presented. A detailed description is given on the decision-making process in early enteral nutrition in a tertiary facility treating puppies with canine parvovirus enteritis.http://www.theveterinarynurse.com/copyright.shtmlhb201

Congenital pyloric mucosal fold resulting in an antral valve outflow obstruction in a bull terrier

An under-sized 3 month old female bull terrier was referred with a history of regurgitation since 3 days of age. Thoracic radiographs were unremarkable, while abdominal radiographs showed a distended stomach, despite a 12 hour fast. Abdominal ultrasonography revealed gastric outflow obstruction of unclear aetiology. Coeliotomy was performed, during which an excessive mucosal fold at the pyloric antrum was excised. Histopathology of the pyloric fold revealed mild oedema and fibrosis of the mucosal tissue. The dog made a complete recovery, with resolution of regurgitation and grew to within the expected breed size. In the authors’ opinion, this is the first canine report of congenital antral mucosal valve resulting in gastric outflow obstruction, and only the second report in any species.http://www3.interscience.wiley.com/journal/117961497hb2013mn201

Undergraduate antibiotic stewardship training : are we leaving our future prescribers ‘flapping in the wind’?

A multisite survey of South African (SA) medical students’ perceptions and knowledge of antibiotic resistance (ABR) and appropriate prescribing by Wasserman et al., published in this edition of the SAMJ, demonstrates that our final-year medical undergraduates are clearly inadequately prepared for practice. Moreover, crucial gaps in knowledge and poor understanding of antibiotic stewardship (AS) and infection control, vary geographically. This first-in-kind crosssectional survey of the preparedness of final-year medical students to prescribe antibiotics identified several enablers that necessitate alternative educational strategies and interventions that could decisively affect the prescribing by graduates. In keeping with a recent study of final-year SA pharmacy students, by far the majority of respondents reported that they would prefer more education on appropriate antibiotic use. In fact, less than two-thirds reported being familiar with the term ‘antibiotic stewardship’. More disconcerting, only a third of respondents felt confident to prescribe antibiotics, with similar proportions across institutions.http://www.samj.org.zaam2017Companion Animal Clinical StudiesPharmacolog

Biomarkers in canine parvovirus enteritis

Canine parvovirus (CPV) enteritis has, since its emergence in 1978, remained a common and important cause of morbidity and mortality in young dogs. The continued incidence of parvoviral enteritis is partly due to the virus’ capability to evolve into more virulent and resistant variants with significant local gastrointestinal and systemic inflammatory sequelae. This paper reviews current knowledge on historical-, signalment-, and clinical factors as well as several haematological-, biochemical- and endocrine parameters that can be used as diagnostic and prognostic biomarkers in CPV enteritis. These factors include season of presentation, purebred nature, bodyweight, vomiting, leukopaenia, lymphopaenia, thrombocytopaenia, hypercoagulability, hypercortisolaemia, hypothyroxinaemia, hypoalbuminaemia, elevated C-reactive protein and tumour necrosis factor, hypocholesterolaemia and hypocitrullinaemia. Factors contributing to the manifestations of CPV infection are multiple with elements of host, pathogen, secondary infections, underlying stressors and environment affecting severity and outcome. The availability of several prognosticators has made identification of patients at high risk of death and their subsequent targeted management more rewarding.http://www.tandfonline.com/loi/tnzv20hj2014mn201