Asymptotic defectiveness of manufacturing plants: an estimate based on process learning curves

The paper describes a method for a preliminary estimation of asymptotic defectiveness of a manufacturing plant based on the prediction of its learning curve estimated during a p-chart setting up. The proposed approach provides process managers with the possibility of estimating the asymptotic variability of the process and the period of revision of p-chart control limits. An application of the method is also provided

Crossover from time-correlated single-electron tunneling to that of Cooper pairs

We have studied charge transport in a one-dimensional chain of small Josephson junctions using a single-electron transistor. We observe a crossover from time-correlated tunneling of single electrons to that of Cooper pairs as a function of both magnetic field and current. At relatively high magnetic field, single-electron transport dominates and the tunneling frequency is given by f=I/e, where I is the current through the chain and e is the electron's charge. As the magnetic field is lowered, the frequency gradually shifts to f=I/2e for I>200 fA, indicating Cooper-pair transport. For the parameters of the measured sample, we expect the Cooper-pair transport to be incoherent.Comment: 5 pages, 4 figures; v2: minor changes, clarifications, addition

Hostility and quality of life among Hispanics/Latinos in the HCHS/SOL Sociocultural Ancillary Study

The purpose of this study was to determine if hostility is associated with physical and mental health-related quality of life (QoL) in U.S. Hispanics/Latinos after accounting for depression and anxiety

Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity.

Background: Hispanics living in the USA may have unrecognized potential birthplace and lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 participants from four centers of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), aged 18 to 74 years old at recruitment.Results: Amplicon sequencing of 16S rRNA gene V4 and fungal ITS1 fragments from self-collected stool samples indicate that the host microbiome is determined by sociodemographic and migration-related variables. Those who relocate from Latin America to the USA at an early age have reductions in Prevotella to Bacteroides ratios that persist across the life course. Shannon index of alpha diversity in fungi and bacteria is low in those who relocate to the USA in early life. In contrast, those who relocate to the USA during adulthood, over 45 years old, have high bacterial and fungal diversity and high Prevotella to Bacteroides ratios, compared to USA-born and childhood arrivals. Low bacterial diversity is associated in turn with obesity. Contrasting with prior studies, our study of the Latino population shows increasing Prevotella to Bacteroides ratio with greater obesity. Taxa within Acidaminococcus, Megasphaera, Ruminococcaceae, Coriobacteriaceae, Clostridiales, Christensenellaceae, YS2 (Cyanobacteria), and Victivallaceae are significantly associated with both obesity and earlier exposure to the USA, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life introduction to the USA.Conclusions: Our analysis of the gut microbiome of Latinos demonstrates unique features that might be responsible for health disparities affecting Hispanics living in the USA

Relation of Diabetes to Cognitive Function in Hispanics/Latinos of Diverse Backgrounds in the United States

Objectives:To examine the association between diabetes and cognitive function within U.S. Hispanics/Latinos of Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American background. Method: This cross-sectional study included 9,609 men and women (mean age = 56.5 years), who are members of the Hispanic Community Health Study/Study of Latinos. We classified participants as having diabetes, prediabetes, or normal glucose regulation. Participants underwent a neurocognitive battery consisting of tests of verbal fluency, delayed recall, and processing speed. Analyses were stratified by Hispanic/Latino subgroup. Results: From fully adjusted linear regression models, compared with having normal glucose regulation, having diabetes was associated with worse processing speed among Cubans (β = −1.99; 95% CI [confidence interval] = [−3.80, −0.19]) and Mexicans (β = −2.26; 95% CI = [−4.02, −0.51]). Compared with having normal glucose regulation, having prediabetes or diabetes was associated with worse delayed recall only among Mexicans (prediabetes: β = −0.34; 95% CI = [−0.63, −0.05] and diabetes: β = −0.41; 95% CI = [−0.79, −0.04]). No associations with verbal fluency. Discussion: The relationship between diabetes and cognitive function varied across Hispanic/Latino subgroup