1,310 research outputs found

    Surveillance at sea: The transactional politics of border control in the Aegean

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    The relationship between vision and action is a key element of both practices and conceptualizations of border surveillance in Europe. This article engages with what we call the ‘operative vision’ of surveillance at sea, specifically as performed by the border control apparatus in the Aegean. We analyse the political consequences of this operative vision by elaborating on three examples of fieldwork conducted in the Aegean and on the islands of Chios and Lesbos. One of the main aims is to bring the figure of the migrant back into the study of border technologies. By combining insights from science and technology studies with border, mobility and security studies, the article distinguishes between processes of intervention, mobilization and realization and emphasizes the role of migrants in their encounter with surveillance operations. Two claims are brought forward. First, engaging with recent scholarly work on the visual politics of border surveillance, we circumscribe an ongoing ‘transactional politics’. Second, the dynamic interplay between vision and action brings about a situation of ‘recalcitrance’, in which mobile objects and subjects of various kinds are drawn into securitized relations, for instance in encounters between coast guard boats and migrant boats at sea. Without reducing migrants to epiphenomena of those relations, this recalcitrance typifies the objects of surveillance as both relatable as well as resistant, particularly in the tensions between border control and search and rescue

    Расчет параметров гидротранспорта высококонцентрированных гидросмесей в условиях предприятий Кривбасса

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    Для технології складування на підприємствах Кривбасу відходів збагачення, згущених до концентрації пасти, запропоновано методики розрахунків параметрів та режимів роботи/ гідротранспортних установок з урахуванням гідравлічних та реологічних характеристик.The methods of calculation of parameters and regimes of hydrotransport plants operation for technology of stocking of cleaning rejects condensed till paste concentration at Krivbas enterprises taking into account hydraulic and rheological characteristics are offered

    Роми України і Миколаївщини

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    У статті розглянуто історію появи ромів на території України. Наприкінці ХVIII ст. 9-а ревізія виявила ромськенаселення уХерсонськійгубернії (територія сучасної Миколаївщини). Зараз у цьому регіоні проживає понад 1500 ромів.В статье рассмотрена история появления ромов на территории Украины. В конце ХVIII ст. 9-я ревизия зафиксировала наличие цыганского населения в Херсонской губернии (территория современной Николаевщины). Сейчас в этом регионе проживает более 1500 ромов.History of appearance of Romanies on the territory of Ukraine is considered in the thesis. At the end of 18th century Romanies are fixed in the 9th revision on the territory of Kherson province (modern Mykolaiv region). There are more than 1500 Romanies in this region now

    Impact of Early Coronary Revascularization on Long-Term Outcomes in Patients With Myocardial Ischemia on Dobutamine Stress Echocardiography

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    The role of early coronary revascularization in the management of stable coronary artery disease remains controversial. The aim of this study was to evaluate the impact of early coronary revascularization on long-term outcomes (>10 years) after an ischemic dobutamine stress echocardiography (DSE) in patients with known or suspected coronary artery disease. Patients without stress-induced ischemia on DSE and those who underwent late coronary revascularization (>90 days after DSE) were excluded. The final study cohort consisted of 905 patients. A DSE with a peak wall motion score index of 1.1 to 1.7 was considered mild

    Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

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    To gain more insight into the pharmacological role of endogenous P-glycoprotein in the metabolism of the widely used substrate drug doxorubicin, we have studied the plasma pharmacokinetics, tissue distribution and excretion of this compound in mdr1a(–/– and wild-type mice. Doxorubicin was administered as an i.v. bolus injection at a dose level of 5 mg kg−1. Drug and metabolite concentrations were determined in plasma, tissues, urine and faeces by high-performance liquid chromatography. In comparison with wild-type mice, the terminal half-life and the area under the plasma concentration–time curve of doxorubicin in it>mdr1a(–/–) mice were 1.6- and 1.2-fold higher respectively.The retention of both doxorubicin and its metabolite doxorubicinol in the hearts of mdr1a(–/–) mice was substantially prolonged. In addition, a significantly increased drug accumulation was observed in the brain and the liver of mdr1a(–/–) mice. The relative accumulation in most other tissues was not or only slightly increased. The differences in cumulative faecal and urinary excretion of doxorubicin and metabolites between both types of mice were small. These experiments demonstrate that the absence of mdr1a P-glycoprotein only slightly alters the plasma pharmacokinetics of oxorubicin. Furthermore, the substantially prolonged presence of both doxorubicin and doxorubicinol in cardiac tissue of mdr1a(–/–) mice suggests that a blockade of endogenous P-glycoprotein in patients, for example by a reversal agent, may enhance the risk of cardiotoxicity upon administration of doxorubicin. © 1999 Cancer Research Campaig

    Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography?

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    Stress echocardiography and myocardial perfusion imaging are commonly used noninvasive imaging modalities for the evaluation of ischaemic heart disease. Both modalities have proved clinically useful in the entire spectrum of coronary artery disease. Both techniques can detect coronary artery disease and provide prognostic information. Both techniques can identify low-risk and high-risk subsets among patients with known or suspected coronary artery disease and thus guide patient management decisions. In patients with acute myocardial infarction, both techniques have been used to identify residual viable tissue and predict improvement of function over time. In patients with chronic ischaemic left ventricular (LV) dysfunction, viability assessment with either modality can be used to predict improvement of function after revascularisation and thus guide patient treatment
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