556 research outputs found
Low relaxation rate in a low-Z alloy of iron
The longest relaxation time and sharpest frequency content in ferromagnetic
precession is determined by the intrinsic (Gilbert) relaxation rate \emph{}.
For many years, pure iron (Fe) has had the lowest known value of for all pure ferromagnetic metals or binary alloys. We show that an
epitaxial iron alloy with vanadium (V) possesses values of which are
significantly reduced, to 355 Mhz at 27% V. The result can be understood
as the role of spin-orbit coupling in generating relaxation, reduced through
the atomic number .Comment: 14 pages, 4 figure
Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea
BACKGROUND: Glioblastoma multiforme is the most malignant form of brain tumor. Despite treatment including surgical resection, adjuvant chemotherapy, and radiation, these tumors typically recur. The recurrent tumor is often resistant to further therapy with the same agent, suggesting that the surviving cells that repopulate the tumor mass have an intrinsic genetic advantage. We previously demonstrated that cells selected for resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) are near-diploid, with over-representation of part or all of chromosomes 7 and 22. While cells from untreated gliomas often have over-representation of chromosome 7, chromosome 22 is typically under-represented. METHODS: We have analyzed cells from primary and recurrent tumors from the same patient before and after in vitro selection for resistance to clinically relevant doses of BCNU. Karyotypic analyses were done to demonstrate the genetic makeup of these cells, and fluorescent in situ hybridization analyses have defined the region(s) of chromosome 22 retained in these BCNU-resistant cells. RESULTS: Karyotypic analyses demonstrated that cells selected for BCNU resistance were near-diploid with over-representation of chromosomes 7 and 22. In cells where whole copies of chromosome 22 were not identified, numerous fragments of this chromosome were retained and inserted into several marker and derivative chromosomes. Fluorescent in situ hybridization analyses using whole chromosome paints confirmed this finding. Additional FISH analysis using bacterial artificial chromosome probes spanning the length of chromosome 22 have allowed us to map the over-represented region to 22q12.3–13.32. CONCLUSION: Cells selected for BCNU resistance either in vivo or in vitro retain sequences mapped to chromosome 22. The specific over-representation of sequences mapped to 22q12.3–13.32 suggest the presence of a DNA sequence important to BCNU survival and/or resistance located in this region of chromosome 22
Modeling core collapse supernovae in 2 and 3 dimensions with spectral neutrino transport
The overwhelming evidence that the core collapse supernova mechanism is
inherently multidimensional, the complexity of the physical processes involved,
and the increasing evidence from simulations that the explosion is marginal
presents great computational challenges for the realistic modeling of this
event, particularly in 3 spatial dimensions. We have developed a code which is
scalable to computations in 3 dimensions which couples PPM Lagrangian with
remap hydrodynamics [1], multigroup, flux-limited diffusion neutrino transport
[2], with many improvements), and a nuclear network [3]. The neutrino transport
is performed in a ray-by-ray plus approximation wherein all the lateral effects
of neutrinos are included (e.g., pressure, velocity corrections, advection)
except the transport. A moving radial grid option permits the evolution to be
carried out from initial core collapse with only modest demands on the number
of radial zones. The inner part of the core is evolved after collapse along
with the rest of the core and mantle by subcycling the lateral evolution near
the center as demanded by the small Courant times. We present results of 2-D
simulations of a symmetric and an asymmetric collapse of both a 15 and an 11 M
progenitor. In each of these simulations we have discovered that once the
oxygen rich material reaches the shock there is a synergistic interplay between
the reduced ram pressure, the energy released by the burning of the shock
heated oxygen rich material, and the neutrino energy deposition which leads to
a revival of the shock and an explosion.Comment: 10 pages, 3 figure
Feigned Consensus: Usurping the Law in Shaken Baby Syndrome/Abusive Head Trauma Prosecutions
Few medico-legal matters have generated as much controversy--both in the medical literature and in the courtroom--as Shaken Baby Syndrome (SBS), now known more broadly as Abusive Head Trauma (AHT). The controversies are of enormous significance in the law because child abuse pediatricians claim, on the basis of a few non-specific medical findings supported by a weak and methodologically flawed research base, to be able to “diagnose” child abuse, and thereby to provide all of the evidence necessary to satisfy all of the legal elements for criminal prosecution (or removal of children from their parents). It is a matter, therefore, in which medical opinion claims to fully occupy the legal field. As controversies flare up increasingly in the legal arena, child abuse pediatricians and prosecutors now respond by claiming both that there is actually no real controversy about SBS/AHT, and that it is a purely medical “diagnosis” and not a legal conclusion, so testimony in support of the SBS hypothesis should not be challenged in court. This article, coauthored by four law professors, two physicians, and a physicist, demonstrates that there is very much a live controversy about the SBS/AHT hypothesis and maintains that, under traditional principles of evidence law, physicians should not be permitted to “diagnose” abuse in court (as opposed to identifying specific symptoms or medical findings)
Triangular mass matrices of quarks and Cabibbo-Kobayashi-Maskawa mixing
Every nonsingular fermion mass matrix, by an appropriate unitary
transformation of right-chiral fields, is equivalent to a triangular matrix.
Using the freedom in choosing bases of right-chiral fields in the minimal
standard model, reduction to triangular form reduces the well-known ambiguities
in reconstructing a mass matrix to trivial phase redefinitions. Furthermore,
diagonalization of the quark mass sectors can be shifted to one charge sector
only, without loosing the concise and economic triangular form. The
corresponding effective triangular mass matrix is reconstructed, up to trivial
phases, from the moduli of the CKM matrix elements, and vice versa, in a unique
way. A new formula for the parametrization independent CP-measure in terms of
observables is derived and discussed.Comment: 13 pages, Late
Integrability and chaos: the classical uncertainty
In recent years there has been a considerable increase in the publishing of
textbooks and monographs covering what was formerly known as random or
irregular deterministic motion, now named by the more fashionable term of
deterministic chaos. There is still substantial interest in a matter that is
included in many graduate and even undergraduate courses on classical
mechanics. Based on the Hamiltonian formalism, the main objective of this
article is to provide, from the physicist's point of view, an overall and
intuitive review of this broad subject (with some emphasis on the KAM theorem
and the stability of planetary motions) which may be useful to both students
and instructors.Comment: 24 pages, 10 figure
Damping of supernova neutrino transitions in stochastic shock-wave density profiles
Supernova neutrino flavor transitions during the shock wave propagation are
known to encode relevant information not only about the matter density profile
but also about unknown neutrino properties, such as the mass hierarchy (normal
or inverted) and the mixing angle theta_13. While previous studies have
focussed on "deterministic" density profiles, we investigate the effect of
possible stochastic matter density fluctuations in the wake of supernova shock
waves. In particular, we study the impact of small-scale fluctuations on the
electron (anti)neutrino survival probability, and on the observable spectra of
inverse-beta-decay events in future water-Cherenkov detectors. We find that
such fluctuations, even with relatively small amplitudes, can have significant
damping effects on the flavor transition pattern, and can partly erase the
shock-wave imprint on the observable time spectra, especially for
sin^2(theta_13) > O(10^-3).Comment: v2 (23 pages, including 6 eps figures). Typos removed, references
updated, matches the published versio
Shell evolution of stable N = 50-56 Zr and Mo nuclei with respect to low-lying octupole excitations
For the N = 50-56 zirconium (Z = 40) and molybdenum (Z = 42) isotopes, the evolution of subshells is evaluated by extracting the effective single-particle energies from available particle-transfer data. The extracted systematic evolution of neutron subshells and the systematics of the excitation energy of the octupole phonons provide evidence for type-II shape coexistence in the Zr isotopes. Employing a simplistic approach, the relative effective single-particle energies are used to estimate whether the formation of low-lying octupole-isovector excitations is possible at the proposed energies. The results raise doubts about this assignment
Renormalization in Quantum Field Theory: An Improved Rigorous Method
The perturbative construction of the S-matrix in the causal spacetime
approach of Epstein and Glaser may be interpreted as a method of regularization
for divergent Feynman diagrams. The results of any method of regularization
must be equivalent to those obtained from the Epstein-Glaser (EG) construction,
within the freedom left by the latter. In particular, the conceptually
well-defined approach of Bogoliubov, Parasuk, Hepp, and Zimmermann (BPHZ),
though conceptually different from EG, meets this requirement. Based on this
equivalence we propose a modified BPHZ procedure which provides a significant
simplification of the techniques of perturbation theory, and which applies
equally well to standard quantum field theory and to chiral theories. We
illustrate the proposed method by a number of examples of various orders in
perturbation theory. At the level of multi-loop diagrams we find that
subdiagrams as classified by Zimmermann's forest formula in BPHZ may be
restricted to subdiagrams in the sense of Epstein-Glaser, thus entailing an
important reduction of actual computations. Furthermore, the relationship of
our approach to the method of dimensional regularization is particularly
transparent, without having to invoke analytic continuation to unphysical
spacetime dimension, and sheds new light on certain parameters within
dimensional regularization.Comment: 19 pages, 3 figure
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