556 research outputs found

    Low relaxation rate in a low-Z alloy of iron

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    The longest relaxation time and sharpest frequency content in ferromagnetic precession is determined by the intrinsic (Gilbert) relaxation rate \emph{GG}. For many years, pure iron (Fe) has had the lowest known value of G=57 MhzG=\textrm{57 Mhz} for all pure ferromagnetic metals or binary alloys. We show that an epitaxial iron alloy with vanadium (V) possesses values of GG which are significantly reduced, to 35±\pm5 Mhz at 27% V. The result can be understood as the role of spin-orbit coupling in generating relaxation, reduced through the atomic number ZZ.Comment: 14 pages, 4 figure

    Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea

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    BACKGROUND: Glioblastoma multiforme is the most malignant form of brain tumor. Despite treatment including surgical resection, adjuvant chemotherapy, and radiation, these tumors typically recur. The recurrent tumor is often resistant to further therapy with the same agent, suggesting that the surviving cells that repopulate the tumor mass have an intrinsic genetic advantage. We previously demonstrated that cells selected for resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) are near-diploid, with over-representation of part or all of chromosomes 7 and 22. While cells from untreated gliomas often have over-representation of chromosome 7, chromosome 22 is typically under-represented. METHODS: We have analyzed cells from primary and recurrent tumors from the same patient before and after in vitro selection for resistance to clinically relevant doses of BCNU. Karyotypic analyses were done to demonstrate the genetic makeup of these cells, and fluorescent in situ hybridization analyses have defined the region(s) of chromosome 22 retained in these BCNU-resistant cells. RESULTS: Karyotypic analyses demonstrated that cells selected for BCNU resistance were near-diploid with over-representation of chromosomes 7 and 22. In cells where whole copies of chromosome 22 were not identified, numerous fragments of this chromosome were retained and inserted into several marker and derivative chromosomes. Fluorescent in situ hybridization analyses using whole chromosome paints confirmed this finding. Additional FISH analysis using bacterial artificial chromosome probes spanning the length of chromosome 22 have allowed us to map the over-represented region to 22q12.3–13.32. CONCLUSION: Cells selected for BCNU resistance either in vivo or in vitro retain sequences mapped to chromosome 22. The specific over-representation of sequences mapped to 22q12.3–13.32 suggest the presence of a DNA sequence important to BCNU survival and/or resistance located in this region of chromosome 22

    Modeling core collapse supernovae in 2 and 3 dimensions with spectral neutrino transport

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    The overwhelming evidence that the core collapse supernova mechanism is inherently multidimensional, the complexity of the physical processes involved, and the increasing evidence from simulations that the explosion is marginal presents great computational challenges for the realistic modeling of this event, particularly in 3 spatial dimensions. We have developed a code which is scalable to computations in 3 dimensions which couples PPM Lagrangian with remap hydrodynamics [1], multigroup, flux-limited diffusion neutrino transport [2], with many improvements), and a nuclear network [3]. The neutrino transport is performed in a ray-by-ray plus approximation wherein all the lateral effects of neutrinos are included (e.g., pressure, velocity corrections, advection) except the transport. A moving radial grid option permits the evolution to be carried out from initial core collapse with only modest demands on the number of radial zones. The inner part of the core is evolved after collapse along with the rest of the core and mantle by subcycling the lateral evolution near the center as demanded by the small Courant times. We present results of 2-D simulations of a symmetric and an asymmetric collapse of both a 15 and an 11 M progenitor. In each of these simulations we have discovered that once the oxygen rich material reaches the shock there is a synergistic interplay between the reduced ram pressure, the energy released by the burning of the shock heated oxygen rich material, and the neutrino energy deposition which leads to a revival of the shock and an explosion.Comment: 10 pages, 3 figure

    Feigned Consensus: Usurping the Law in Shaken Baby Syndrome/Abusive Head Trauma Prosecutions

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    Few medico-legal matters have generated as much controversy--both in the medical literature and in the courtroom--as Shaken Baby Syndrome (SBS), now known more broadly as Abusive Head Trauma (AHT). The controversies are of enormous significance in the law because child abuse pediatricians claim, on the basis of a few non-specific medical findings supported by a weak and methodologically flawed research base, to be able to “diagnose” child abuse, and thereby to provide all of the evidence necessary to satisfy all of the legal elements for criminal prosecution (or removal of children from their parents). It is a matter, therefore, in which medical opinion claims to fully occupy the legal field. As controversies flare up increasingly in the legal arena, child abuse pediatricians and prosecutors now respond by claiming both that there is actually no real controversy about SBS/AHT, and that it is a purely medical “diagnosis” and not a legal conclusion, so testimony in support of the SBS hypothesis should not be challenged in court. This article, coauthored by four law professors, two physicians, and a physicist, demonstrates that there is very much a live controversy about the SBS/AHT hypothesis and maintains that, under traditional principles of evidence law, physicians should not be permitted to “diagnose” abuse in court (as opposed to identifying specific symptoms or medical findings)

    Triangular mass matrices of quarks and Cabibbo-Kobayashi-Maskawa mixing

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    Every nonsingular fermion mass matrix, by an appropriate unitary transformation of right-chiral fields, is equivalent to a triangular matrix. Using the freedom in choosing bases of right-chiral fields in the minimal standard model, reduction to triangular form reduces the well-known ambiguities in reconstructing a mass matrix to trivial phase redefinitions. Furthermore, diagonalization of the quark mass sectors can be shifted to one charge sector only, without loosing the concise and economic triangular form. The corresponding effective triangular mass matrix is reconstructed, up to trivial phases, from the moduli of the CKM matrix elements, and vice versa, in a unique way. A new formula for the parametrization independent CP-measure in terms of observables is derived and discussed.Comment: 13 pages, Late

    Integrability and chaos: the classical uncertainty

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    In recent years there has been a considerable increase in the publishing of textbooks and monographs covering what was formerly known as random or irregular deterministic motion, now named by the more fashionable term of deterministic chaos. There is still substantial interest in a matter that is included in many graduate and even undergraduate courses on classical mechanics. Based on the Hamiltonian formalism, the main objective of this article is to provide, from the physicist's point of view, an overall and intuitive review of this broad subject (with some emphasis on the KAM theorem and the stability of planetary motions) which may be useful to both students and instructors.Comment: 24 pages, 10 figure

    Damping of supernova neutrino transitions in stochastic shock-wave density profiles

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    Supernova neutrino flavor transitions during the shock wave propagation are known to encode relevant information not only about the matter density profile but also about unknown neutrino properties, such as the mass hierarchy (normal or inverted) and the mixing angle theta_13. While previous studies have focussed on "deterministic" density profiles, we investigate the effect of possible stochastic matter density fluctuations in the wake of supernova shock waves. In particular, we study the impact of small-scale fluctuations on the electron (anti)neutrino survival probability, and on the observable spectra of inverse-beta-decay events in future water-Cherenkov detectors. We find that such fluctuations, even with relatively small amplitudes, can have significant damping effects on the flavor transition pattern, and can partly erase the shock-wave imprint on the observable time spectra, especially for sin^2(theta_13) > O(10^-3).Comment: v2 (23 pages, including 6 eps figures). Typos removed, references updated, matches the published versio

    Shell evolution of stable N = 50-56 Zr and Mo nuclei with respect to low-lying octupole excitations

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    For the N = 50-56 zirconium (Z = 40) and molybdenum (Z = 42) isotopes, the evolution of subshells is evaluated by extracting the effective single-particle energies from available particle-transfer data. The extracted systematic evolution of neutron subshells and the systematics of the excitation energy of the octupole phonons provide evidence for type-II shape coexistence in the Zr isotopes. Employing a simplistic approach, the relative effective single-particle energies are used to estimate whether the formation of low-lying octupole-isovector excitations is possible at the proposed energies. The results raise doubts about this assignment

    Renormalization in Quantum Field Theory: An Improved Rigorous Method

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    The perturbative construction of the S-matrix in the causal spacetime approach of Epstein and Glaser may be interpreted as a method of regularization for divergent Feynman diagrams. The results of any method of regularization must be equivalent to those obtained from the Epstein-Glaser (EG) construction, within the freedom left by the latter. In particular, the conceptually well-defined approach of Bogoliubov, Parasuk, Hepp, and Zimmermann (BPHZ), though conceptually different from EG, meets this requirement. Based on this equivalence we propose a modified BPHZ procedure which provides a significant simplification of the techniques of perturbation theory, and which applies equally well to standard quantum field theory and to chiral theories. We illustrate the proposed method by a number of examples of various orders in perturbation theory. At the level of multi-loop diagrams we find that subdiagrams as classified by Zimmermann's forest formula in BPHZ may be restricted to subdiagrams in the sense of Epstein-Glaser, thus entailing an important reduction of actual computations. Furthermore, the relationship of our approach to the method of dimensional regularization is particularly transparent, without having to invoke analytic continuation to unphysical spacetime dimension, and sheds new light on certain parameters within dimensional regularization.Comment: 19 pages, 3 figure
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