Parametric synthesis of assembly device for fitting rubber sealing ring into the inner groove of the basic item

On the basis of the block diagram of the assembly device technological system a group of morphological matrices of various hierarchy levels may be built. The analysis of the engineering system “ the assembly device for assembly Seal of connections ” is manufactured. The structure of the engineering system and e ё of units at different hierarchical levels is defined, the links between subsystems are detected. On the basis of the skeleton diagram of the assembly device the group of morphological matrixes, different levels of hierarchy is constructed. The synthesis of variants of structure of the assembly device is manufactured

Plasma chemical purification of flue gases using pulsed electron beams

The article presents the study of the pulsed electron beam propagation in oxygen and nitrogen. The researches were performed using the TEA-500 pulsed electron accelerator and drift tube. Parameters of the TEA-500 pulsed electron accelerator are as follows: the electron energy (varies) is 200-450 keV, the beam current is 10 kA, the half-amplitude current pulse duration is 60 ns, the pulse repetition rate is up to 10 Hz (in the pulse burst). The accelerator is equipped with the necessary means of diagnostics of the beam parameters: particle energy, current and current density, the total energy transferred by the beam. The drift tube includes a chamber consisting of two sections of reverse current shunts located along the entire length of the drift tube. The following precursors used N2 and O2. The specified types of gases were chosen as they are among the main components of the flue gases, whose treatment has been widely reported recently

Propagation of the pulsed electron beam of nanosecond duration in gas composition of high pressure

This paper presents the results of the investigation of the propagation of an electron beam in the high-pressure gas compositions (50, 300, and 760 Torr): sulfur hexafluoride and hydrogen, sulfur hexafluoride and nitrogen, sulfur hexafluoride and argon. The experiments have been performed using the TEA-500 laboratory accelerator. The main parameters of the accelerator are as follows: an accelerating voltage of 500 kV; an electron beam current of 10 kA; a pulse width at half maximum of 60 ns; a pulse energy of 200 J; a pulse repetition rate of up to 5 pulses per second, a beam diameter of 5 cm. The pulsed electron beam was injected into a 55 cm metal drift tube. The drift tube is equipped with three reverse-current shunts with simultaneous detecting of signals. The obtained results of the investigation make it possible to conclude that the picture of the processes occurring in the interaction of an electron beam in the high-pressure gas compositions is different from that observed in the propagation of the electron beam in the low-pressure gas compositions (1 Torr)

Electrospark method for obtaining nanopowders

In the paper, a metallic FexOy nanopowder was obtained by the electrospark method. The used electrospark installation consists of the electrode system, mobility system, system for measuring processing parameters (oscilloscope and current sensor, HV voltage divider, manovacuum meter), source of current pulses, vacuum system (vacuum pump, gas cylinders with working gas, gas routes, gas taps). The specific feature of the installation is the use of a power supply circuit of two generators with different voltage levels operating for one interelectrode gap. This generator circuit makes it possible to change the treatment parameters in wide ranges (pulse duration 10–100 ?s, pulse energy 0.1–0.6 J, pulse repetition rate 0.1–5 kHz). It will enable to choose the optimal ratio between the energy expended and the maximum yield of the product, as well as to study the influence of treatment parameters on the composition and properties of the resulting powder. The morphology and phase composition of the FexOy synthesized metal powder was studied

Optical properties of SixTiyCzOw composite nanopowder obtained by pulsed plasma chemical method

This paper presents the results of an experimental investigation on the optical properties of the SixTi<yCzOw nanopowders, produced by the pulsed plasma chemical method. Pulsed plasma chemical synthesis is realized on the laboratory stand, including a plasma chemical reactor (6 l) and TEA-500 electron accelerator. The parameters of the electron beam are as follows: 400-450 keV electron energy, 60 ns half-amplitude pulse duration, up to 200 J pulse energy, and 5 cm beam diameter. The spectrum of the diffuse reflection coefficient R(hv) was measured using the AvaSpec-2048-2 (Avantes) spectrometer with the AvaLight-DHS light source (deuterium and halogen-tungsten lamp) and an integrating sphere. The band gap of the obtained composite is 2.03–3.12 eV

Precision improvement of MEMS gyros for indoor mobile robots with horizontal motion inspired by methods of TRIZ

In the paper, the problem of precision improvement for the MEMS gyrosensors on indoor robots with horizontal motion is solved by methods of TRIZ ("the theory of inventive problem solving").Comment: 6 pages, the paper is accepted to 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, Hawaii, USA (IEEE-NEMS 2014) as an oral presentatio

Investigation of the effect of condensed phase on the energy conditions for the initiation of the plasma-chemical process of flue gas cleaning by a pulsed electron beam

This work investigates the processes of dissipation of the charge and energy of a pulsed electron beam in gas compositions (nitrogen, carbon dioxide and oxygen) in the presence of ammonium sulphate and nitrate. A pulsed electron beam generated by the TEA500 accelerator (Tomsk, Russia) with an electron energy of up to 410 keV, a beam current of up to 5 kA (I0), and a half-amplitude voltage pulse duration of 60 ns was injected into a 46 cm long drift chamber filled with a gas mixture. The pulsed electron beam current (IF?) passing through the drift chamber was registered using a sectioned calorimeter with beam charge monitor function, and the efficiency of the current passage of the beam was determined as the ratio qF?/q0, where q0 is the beam charge measured at the place of its injection into the chamber drift. The pressure in the drift chamber varied (375, 560 and 760 Torr, humidity value 15% ± 5% and 50% ± 5%). The geometric dimensions of the plasma-chemical reactor for initiating plasma-chemical reactions of flue gas cleaning were determined

Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis : APLIOS, a randomized phase-2 study

Background: Ofatumumab, the first fully human anti-CD20 monoclonal antibody, is approved in several countries for relapsing multiple sclerosis (RMS). Objective: To demonstrate the bioequivalence of ofatumumab administered by an autoinjector versus a pre-filled syringe (PFS) and to explore the effect of ofatumumab on B-cell depletion. Methods: APLIOS (NCT03560739) is a 12-week, open-label, parallel-group, phase-2 study in patients with RMS receiving subcutaneous ofatumumab 20 mg every 4 weeks (q4w) (from Week 4, after initial doses on Days 1, 7, and 14). Patients were randomized 10:10:1:1 to autoinjector or PFS in the abdomen, or autoinjector or PFS in the thigh, respectively. Bioequivalence was determined by area under the curve (AUCτ) and maximum plasma concentration (Cmax) for Weeks 8-12. B-cell depletion and safety/tolerability were assessed. Results: A total of 256 patients contributed to the bioequivalence analyses (autoinjector-abdomen, n = 128; PFS-abdomen, n = 128). Abdominal ofatumumab pharmacokinetic exposure was bioequivalent for autoinjector and PFS (geometric mean AUCτ, 487.7 vs 474.1 h × µg/mL (ratio 1.03); Cmax, 1.409 vs 1.409 µg/mL (ratio 1.00)). B-cell counts (median cells/µL) depleted rapidly in all groups from 214.0 (baseline) to 2.0 (Day 14). Ofatumumab was well tolerated. Conclusion: Ofatumumab 20 mg q4w self-administered subcutaneously via autoinjector is bioequivalent to PFS administration and provides rapid B-cell depletion