1,253 research outputs found

    Wish You Were Waiting For Me

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    Illustration of men and women waitinghttps://scholarsjunction.msstate.edu/cht-sheet-music/6815/thumbnail.jp

    Adenosine Diphosphate-Induced Platelet Aggregation and Hypercholesterolemia

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    A paper read by David J. Saxon before the Federation of American Societies for Experimental Biology in April of 1991 on how platelet aggregation may contribute to the development of atherosclerosis and thrombi

    Acid Phosphate Activity in Tobacco Mosaic Virus Susceptible and Hypersensitive Varieties of Burley Tobacco

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    A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by David J. Saxon on January 23, 1968

    Screening for Hyperlipoproteinemia

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    A report submitted to the Faculty Research Committee by David J. Saxon in 1975 on screening for hyperlipoproteinemia

    Thromboxane A2 Generation by Thrombocytes of White Carneau Pigeons

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    Platelet Response in Hypercholesterol Blood to Thrombin-Induced Aggression

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    A report submitted by David J. Saxon to the Research and Creative Productions Committee in 1989 on whether hypercholesterol platelets are more responsive than normocholesterolemic platelets to thrombin-induced aggregation in whole blood

    Interview with David S. Saxon

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    An interview in January 1997 with David S. Saxon, president emeritus of the University of California, who initiated plans during his presidency (1975-1983) for what became the W. M. Keck Observatory on Mauna Kea, operated by CARA, the California Association for Research in Astronomy, a joint enterprise of Caltech, the University of California, and NASA. In this brief interview, Dr. Saxon recalls his intention to bolster UC’s eminence in astronomy; his early discussions with Donald Osterbrock and Charles Townes; discussion with Jerry Nelson of Lawrence Berkeley Laboratory who wanted to build a new-generation telescope with a ten-meter segmented mirror; Luis Alvarez’s support of the idea; financial support from the UC Regents; committee chaired by Harold Ticho of UCLA to initiate design study. He recalls his disagreement with the UC astronomers, who wanted a ten-meter mirror but not a segmented one and were reluctant to collaborate with another institution. He discusses the initial interest of Caltech president Marvin L. [Murph] Goldberger, the fund-raising efforts of Eugene Trefethen, and the abortive $36-million gift to UC from the Hoffman Foundation. He also comments on other achievements of his presidency: revision of UC’s library system and the development of computational information systems

    Cross-Sectional Analysis of Silicon Metal Oxide Semiconductor Devices Using the Scanning Electron Microscope

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    A technique has been developed which enables one to cross-section specific devices or features for examination with the scanning electron microscope (SEM). This method is used for investigation of all facets of microelectronic circuit manufacture from research and development to failure analysis of the finished product. Selective etching is used to provide contrast to each processed layer. Etch type and sequence, used for delineation, are important to understand since they may add artifacts to the cross-section, leading to erroneous analysis conclusions. The etchant and etch conditions used will be dictated by the information needed from a particular sample. Etching systems based on HF-HNO3-H2O are used with metal oxide semiconductor (MOS) technologies. In addition, buffered silicon dioxide etches are also used especially to delineate silicon dioxide layers. Cross-sectional analysis enables measurement of processing parameters such as junction depth, channel length, layer thickness and length, layer composition and step coverage

    College-entry level biology aligned to high school and middle school curriculum

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    Abstract Many students believe they are equipped for college only to discover that they need additional preparation in understanding how to apply content and/or improvement of study skills. How can public schools work together with colleges to better prepare students? Great scrutiny of the curriculum in conjunction with determination of college-entrance readiness can determine needs. This paper describes an examination of 7-12 science curriculum in an Eastern Kentucky public school system and entry-level readiness in sections of a biology class at a regional Kentucky university. Results indicated that students at greatest readiness tended to score a B in entry-level courses. In response to the readiness and performance findings, teachers in grades 7-12 called for more vertical alignment of curriculum, traditional classes instead of block scheduling, a change in diploma options, and more science unit requirements for a high school diploma

    Oral diabetes medication monotherapy and short-term mortality in individuals with type 2 diabetes and coronary artery disease

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    Objective To determine whether sulfonylurea use, compared with non-sulfonylurea oral diabetes medication use, was associated with 2-year mortality in individuals with well-controlled diabetes and coronary artery disease (CAD). Research design and methods We studied 5352 US veterans with type 2 diabetes, obstructive CAD on coronary angiography, hemoglobin A1c ≤7.5% at the time of catheterization, and taking zero or one oral diabetes medication (categorized as no medications, non-sulfonylurea medication, or sulfonylurea). We estimated the association between medication category and 2-year mortality using inverse probability of treatment-weighted (IPW) standardized mortality differences and IPW multivariable Cox proportional hazards regression. Results 49%, 35%, and 16% of the participants were on no diabetes medications, non-sulfonylurea medications, and sulfonylureas, respectively. In individuals on no medications, non-sulfonylurea medications, and sulfonylureas, the unadjusted mortality rates were 6.6%, 5.2%, and 11.9%, respectively, and the IPW-standardized mortality rates were 5.9%, 6.5%, and 9.7%, respectively. The standardized absolute 2-year mortality difference between non-sulfonylurea and sulfonylurea groups was 3.2% (95% CI 0.7 to 5.7) (p=0.01). In Cox proportional hazards models, the point estimate suggested that sulfonylurea use might be associated with greater hazard of mortality than non-sulfonylurea medication use, but this finding was not statistically significant (HR 1.38 (95% CI 1.00 to 1.93), p=0.05). We did not observe significant mortality differences between individuals on no diabetes medications and non-sulfonylurea users. Conclusions Sulfonylurea use was common (nearly one-third of those taking medications) and was associated with increased 2-year mortality in individuals with obstructive CAD. The significance of the association between sulfonylurea use and mortality was attenuated in fully adjusted survival models. Caution with sulfonylurea use may be warranted for patients with well-controlled diabetes and CAD, and metformin or newer diabetes medications with cardiovascular safety data could be considered as alternatives when individualizing therapy
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