4 research outputs found
Ultrasound promoted asymmetric transfer hydrogenation of ketones using Ru(II)arene/amino alcohol catalyst system
Asymmetric transfer hydrogenation of ketones using Ru(II)arene/amino alcohol catalyst system proceeds with significant rate enhancement by ultrasound promotion. Comparison of the silent reactions carried out at 25 °C with reactions under sonochemical activation at 25 °C clearly showed enhancement in catalytic activity by 5-10 times without significantly affecting the enantioselectivity
Catalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl<SUB>2</SUB>]<SUB>2</SUB> with chiral amino alcohol ligands
Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl<SUB>2</SUB>]<SUB>2</SUB> and new derivatives of β-amino alcohols synthesized from (S)-(-)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%)
Environmentally benign synthesis of β-hydroxy sulfides using cyclic carbonates catalyzed by large-pore zeolites
Asymmetric Transfer Hydrogenation of Imines in Water by Varying the Ratio of Formic Acid to Triethylamine
Asymmetric transfer
hydrogenation (ATH) of imines has been performed with variation in
formic acid (F) and triethylamine (T) molar ratios in water. The F/T
ratio is shown to affect both the reduction rate and enantioselectivity,
with the optimum ratio being 1.1 in the ATH of imines with the Rh-(1<i>S</i>,2<i>S</i>)-TsDPEN catalyst. Use of methanol
as a cosolvent enhanced reduction activity. A variety of imine substrates
have been reduced, affording high yields (94–98%) and good
to excellent enantioselectivities (89–98%). In comparison with
the common azeotropic F–T system, the reduction with 1.1/1
F/T is faster