60 research outputs found

    Reducing the Number of Forward Nodes from 1-Hop Nodes to Cover 2-Hop Nodes with Network Coding

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    All neighbors of a node can receive a data packet conveyed by a broadcasting node in an ad-hoc wireless network. In this way, the no. of forwarding nodes is utilized as the cost criterion for propagation. Among different estimation approaches, the researcher uses 1-Hop nodes to cover entire 2- Hop nodes utilizing 2-hop region information to decrease repetitive communicates. We dissect a few deficiencies of this approach and propose an improved algorithm along with the network coding concepts in this paper. Our algorithm utilizes 2-hop neighborhood more successfully to lessen excess communicates. The Simulation results of applying this algorithm demonstrate performance improvements. Nowadays the scientists are acquainting the idea of Network coding to neighbour topology aware protocols that beats the excess number of broadcast by victimization the using XOR of data packets. We have made an endeavor to seek out the network coding gain. We’ve shown simulation, implementation and breakdown of result in various circumstances

    Application of Cellulose Derivatives in Mineral Processing

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    Cellulose derivatives (CDs) have been recognized as an anionic water-soluble, non-toxic, biocompatible and biodegradable polysaccharide. The CDs have been used as a viscosity regulator, thickening agent, sizing agent and coating agent and emulsion stabilizer, electrode binder in various industries. These characteristics properties of CDs are associated with hydroxyl groups/functionalized groups present in their structure. The CDs have significant advantages in various fields including several industrial applications such as mineral processing, palletisation process, oil drilling industrial applications due to their non-toxic and selective properties. Moreover, The CDs have been extensively used as a depressant, dispersant as well as flocculants in mineral processing from various ores. During the mineral processing like flotation of sulfide minerals highly toxic inorganic species were used as dispersant and depressant which ultimately cases environmental toxicity. Therefore, there is a current need to introduce CDs as various alternative nontoxic dispersant and flocculants. This chapter emphasized an overview of the application of CDs in mineral processing including the structure, properties of the commonly used minerals processing

    In silico screening of some naturally occurring bioactive compounds predicts potential inhibitors against SARS-COV-2 (COVID-19) protease

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    The reports pertaining to the mitigation and treatment of the COVID-19 pandemic are still lacking. Compatibility of the natural products and availability of the modern computational techniques motivated us to carry out In Silico investigations on some bioactive natural compounds reportedly found in the fruits and leaves of Anthocephalus Cadamba commonly known as Kadam or Kadamb Tree, aiming to predict the potential inhibitors against the aforesaid virus. Having modeled the ground state ligand structure of the nine natural compounds applying density functional theory at B3LYP/631+G (d, p) level, we have performed their molecular docking with SARS-COV-2 protease to calculate the binding affinity as well as to screen the binding at S-protein site during ligand-protein interactions. Out of these nine studied naturally occurring compounds; Oleanic Acid has been appeared to be a potential inhibitor for COVID-19 followed by Ursolic Acid, Iso-Vallesiachotamine, Vallesiachotamine, Cadambine, Vincosamide-N-Oxide, Isodihydroamino-cadambine, Pentyle Ester of Chlorogenic Acid and D-Myo-Inositol. Hence, these bioactive natural compounds or their structural analogs may be explored as an anti-COVID-19 drug agents. The solubility and solvent-effect related to the phytochemicals may be the point of concern. In vivo investigations on these proposed natural compounds or their structural analogs are invited for designing and developing the potential medicine/vaccine for the treatment of COVID-19 pandemic

    Identification of Comamonas species using 16S rRNA gene sequence

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    A bacterial strain Bz02 was isolated from a water sample collected from river Gomti at the Indian city of Lucknow. We characterized the strain using 16S rRNA sequence. Phylogenetic analysis showed that the strain formed a monophyletic clade with members of the genus Comamonas. The closest phylogenetic relative was Comamonas testosteroni with 95% 16S rRNA gene sequence similarity. It is proposed that the identified strain Bz02 be assigned as the type strain of a species of the genus Comamonas (Comamonas sp Bz02) based on 16S rRNA gene sequence search in Ribosomal Database Project, small subunit rRNA and large subunit rRNA databases together with the phylogenetic tree analysis. The sequence is deposted in GenBank with the accession number FJ211417

    Removal of Arsenic - “A Silent Killer” in the Environment by Adsorption Methods

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    Water is one of the most essential requirements for living being to survive because 70–80% of the mass of most living bodies consists of water and various mineral and organic salts. Water is also most important component of our environment. Large amount of water is used in various industries or commercial level or domestic level and finally effluent water is loaded with large amount of pollutants such as organic chemicals (surfactants, dyes, phenols etc.), inorganic hazardous heavy metals (As in present case) microbes (bacteria, fungi etc.) pollutants particulate etc. Arsenic is a natural metalloid chemical that may be present in groundwater and surface water gets polluted, hence, aquatic life of plants and animals is disturbed and cause abnormal growth and various diseases, hence, short term or long term changes occurs in ecosystem. Hence, treatment of wastewater is essentially required before discharge effluent wastewater into ponds or lagoons, drains and rivers. Arsenic is one such element that contaminates the environment as reported in several countries. The largest population at risk is in Bangladesh followed by India (West Bengal). Arsenic is familiar as silent killer because dissolved in water, it is colorless, odorless, and tasteless, yet consumption of relatively small doses of this element in its most toxic forms can cause rapid and violent death. It is a human carcinogen in water over a wide range of pH values, having harmful effects on both human health and environment, even at low concentration. Because of this effect, the World Health Organization (WHO) and the US Environmental Protection Agency (USEPA) set the arsenic standard for drinking water at .010 ppm to protect consumers served by public water systems. Ingestion only poses health problems if a dangerous amount of arsenic enters the body. Then, it can lead to cancer, liver disease, coma, and death. There is no effective treatment for arsenic toxicity. Only the removal of arsenic from aqueous system can prevent the toxicity. A great deal of research over recent decades has been done to lower the concentration of arsenic in drinking water and still there is a need to develop ecofriendly techniques. Existing major arsenic removal technologies include oxidation, adsorption, precipitation, coagulation and membrane separation. This book chapter presents a systematic description of current status of research in the area of arsenic removal from contaminated water and comparison of all technologies available with more emphasis on adsorption

    Structure and Properties of Dyes and Pigments

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    Colour is one of the elements of nature that makes human life more aesthetic and fascinating in the world. Plants, animals, and minerals have been used as primary sources for colourants, dyes or pigments since ancient times. In our daily life, we know about many substances which have specific colours. These are the substances which are used as colourants i.e.; colour imparting species. Both dyes and pigments are coloured as they absorb only some wavelength of visible light. Their structures have Aryl rings that have delocalized electron systems. These structures are said to be responsible for the absorption of electromagnetic radiation that has varying wavelengths, based upon the energy of the electron clouds. Dyes are coloured organic compounds that are used to impart colour to various substrates, including paper, leather, fur, hair, drugs, cosmetics, waxes, greases, plastics and textile materials. A Dye is a coloured compound due to the presence of chromophore and its fixed property to the acid or basic groups such as OH, SO3H, NH2, NR2, etc. The polar auxochrome makes the dye water-soluble and binds the dye to the fabric by interaction with the oppositely charged groups of the fabric structure. Pigments are organic and inorganic compounds which are practically insoluble in medium in which they are incorporated. Dyes and pigments are the most important colourants used to add colour or to change the colour of something. They are widely used in the textile, pharmaceutical, food, cosmetics, plastics, paint, ink, photographic and paper industries. This chapter is devoted to the structure and properties of dyes and pigments

    AlexaTM 20B: Few-Shot Learning Using a Large-Scale Multilingual Seq2Seq Model

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    In this work, we demonstrate that multilingual large-scale sequence-to-sequence (seq2seq) models, pre-trained on a mixture of denoising and Causal Language Modeling (CLM) tasks, are more efficient few-shot learners than decoder-only models on various tasks. In particular, we train a 20 billion parameter multilingual seq2seq model called Alexa Teacher Model (AlexaTM 20B) and show that it achieves state-of-the-art (SOTA) performance on 1-shot summarization tasks, outperforming a much larger 540B PaLM decoder model. AlexaTM 20B also achieves SOTA in 1-shot machine translation, especially for low-resource languages, across almost all language pairs supported by the model (Arabic, English, French, German, Hindi, Italian, Japanese, Marathi, Portuguese, Spanish, Tamil, and Telugu) on Flores-101 dataset. We also show in zero-shot setting, AlexaTM 20B outperforms GPT3 (175B) on SuperGLUE and SQuADv2 datasets and provides SOTA performance on multilingual tasks such as XNLI, XCOPA, Paws-X, and XWinograd. Overall, our results present a compelling case for seq2seq models as a powerful alternative to decoder-only models for Large-scale Language Model (LLM) training

    Robust estimation of bacterial cell count from optical density

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    Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
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