4 research outputs found
The combined effects of on-road and simulator training with feedback on older drivers' on-road performance: Evidence from a randomized controlled trial
<p><b>Objective</b>: A number of training programs that seek to improve driving performance among older drivers are available accompanied by a growing interest in their effectiveness. The purpose of the present investigation was to examine the combined effect of (1) basic in-class training (BT); (2) on-road training with individualized feedback (OR); and (3) training on a driving simulator (S).</p> <p><b>Methods</b>: Using a randomized controlled trial study design, 78 older drivers were randomly assigned to one of 3 groups (BT, BT + OR, or BT + OR + S). All participants completed a pre- and postintervention on-road driving evaluation on a standardized route. The driving evaluations were recorded using video and Global Positioning System (GPS) equipment and were scored by a blind assessor.</p> <p><b>Results</b>: The results indicated a significant reduction of approximately 30% in overall number of driving errors/omissions among participants in the BT + OR and the BT + OR + S groups in comparison to participants in the BT group.</p> <p><b>Conclusions</b>: This study adds to the mounting evidence demonstrating the effectiveness of individualized driver training in improving safe driving among older adults.</p
Additional file 3: Figures S1-S4. of Actionable gene-based classification toward precision medicine in gastric cancer
Figure S1. Definition of somatic copy number alteration (SCNA) status. Figure S2. Clinicopathological characteristics of TCGA molecular subtype in Japanese and TCGA gastric cancers (GCs). Figure S3. Cluster of 435-gene co-mutation patterns. Figure S4. Distribution of Lauren classification and TCGA molecular subtypes by presence or absence of actionable gene alterations. (PDF 725Â kb
Additional file 2: Table S2. of Actionable gene-based classification toward precision medicine in gastric cancer
Detail of the 435-gene panel. (XLSX 16 kb
Additional file 1: Table S1. of Actionable gene-based classification toward precision medicine in gastric cancer
Clinicopathological characteristics of 207 Japanese gastric cancers. (XLSX 38 kb