Cytogenetic characterization of two marine ornamental fishes, Chaetodon collare and Stegastes insularis

The results of the Cytogenetic studies carried out in two marine ornamental fishes, Chaetodon rollare and Stegastes insularis, occurring in the south-eastem Arabian Sea, by Giemsa staining and nuckolar organizer regions (Ag-NOR) staining are reported. The diploid chromosome number (2n) in C. collare and S. insularis was found to be 48. Based on the karyomorphology, the karyotype formula was derived as 48t (FN=48) and 14m + 24 sm + 6st + 4 t (FN=86), respectively for these two species. Silver staining revealed presence of one pair of NORs in both the species. This is the first description of karyotypes in these species using conventional staining and chromosome banding techniques

Cytogenetic studies of fish species Horabagrus nigricollaris, Puntius denisonii and Puntius sarana subnasutus endemic to the Western Ghats

Cytogenetic studies of fish species Horabagrus nigricollaris, Puntius denisonii and Puntius sarana subnasutus endemic to the Western Ghat

Farm level technical efficiency for pulse production in India

Pulses are complementary to cereals both in production as well as in consumption. During the production process, pulses help in improving sustainability by (i) fixing the atmospheric nitrogen into the soil (ii) consuming less water and (iii) controlling diseases and pests. On consumption front, pulses reduce malnutrition and improve human health being a rich and most viable source of protein for vegetarians and poor people. Realizing the importance of pulses, the government of India announces various schemes and programs from time to time to promote the cultivation of pulses in the country. However, pulse production in India has not achieved the targeted level. The paper analyses the production trend of pulses over the last decade and identifies the gap between the targets and achievements. Plot level data from cost of cultivation scheme across major pulses growing states has been used to estimate technical efficiencies of the pulses using data envelopment analysis. The paper also highlights the yield gap of the pulses across major pulse growing states and suggests suitable measures for improving farm level profitability and sustainability by increasing technical efficiency. The study postulated the hypothesis that technical efficiency of the pulses is low and the yield potential of the pulses are not fully harnessed. The results revealed that increase of technical efficiency by 1% will reduce the yield gap by 9 kg per ha and increase total pulse production of the country by 225 thousand tons

Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells

BACKGROUND: Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lumen could be life threatening in asthma and chronic obstructive pulmonary disease patients. Inflammatory cytokines such as IL-13 mediate the transformation of airway ciliary epithelial cells to mucin-secreting goblet cells in acute as well as chronic airway inflammatory diseases. However, no effective and specific pharmacologic treatment is currently available. Here, we investigated the mechanisms by which aldose reductase (AR) regulates the mucus cell metaplasia in vitro and in vivo. METHODOLOGY/FINDINGS: Metaplasia in primary human small airway epithelial cells (SAEC) was induced by a Th2 cytokine, IL-13, without or with AR inhibitor, fidarestat. After 48 h of incubation with IL-13 a large number of SAEC were transformed into goblet cells as determined by periodic acid-schiff (PAS)-staining and immunohistochemistry using antibodies against Mucin5AC. Further, IL-13 significantly increased the expression of Mucin5AC at mRNA and protein levels. These changes were significantly prevented by treatment of the SAEC with AR inhibitor. AR inhibition also decreased IL-13-induced expression of Muc5AC, Muc5B, and SPDEF, and phosphorylation of JAK-1, ERK1/2 and STAT-6. In a mouse model of ragweed pollen extract (RWE)-induced allergic asthma treatment with fidarestat prevented the expression of IL-13, phosphorylation of STAT-6 and transformation of epithelial cells to goblet cells in the lung. Additionally, while the AR-null mice were resistant, wild-type mice showed goblet cell metaplasia after challenge with RWE. CONCLUSIONS: The results show that exposure of SAEC to IL-13 caused goblet cell metaplasia, which was significantly prevented by AR inhibition. Administration of fidarestat to mice prevented RWE-induced goblet cell metaplasia and AR null mice were largely resistant to allergen induced changes in the lung. Thus our results indicate that AR inhibitors such as fidarestat could be developed as therapeutic agents to prevent goblet cell metaplasia in asthma and related pathologies

Report of the Task Force on Enhancing technology use in agriculture insurance

Pradhan Mantri Fasal Bima Yojana (PMFBY) is a flagship scheme of the Government of India to provide insurance coverage and financial support to farmers in the event of failure of any of the notified crops, unsown area and damage to harvest produce as a result of natural calamities, pests and diseases to stabilise the income of farmers, and to encourage them to adopt modern agricultural practices. The scheme is a considerable improvement over all previous insurance schemes in India and is heavily subsidised by the state and central governments. The scheme aims to cover 50 percent of the farming households within next 3 years. During its implementation in the last one season, several challenges relating to enrolment, yield estimation, loss assessment, and claim settlement were reported by farmers, insurance companies as well as the state governments. It was also noted that several technological opportunities existed for possibly leveraging support to the Indian crop insurance program for enhanced efficiency and effectiveness. NITI Aayog of the Government of India, therefore, constituted a Task Force to deliberate on this subject and identify such potential opportunities. This report summarises the recommendations of the Task Force. The Task Force constituted to address the issue of technology support to crop insurance comprised the following 5 sub-groups: (1) Remote Sensing & Drones; (2) Decision Support Systems, Crop Modelling & Integrated Approaches; (3) IT/ICT in Insurance; (4) Crop Cutting Experiments (CCEs); and (5) Technologies for Livestock and Aquaculture Insurance. Each sub-group had several discussions with experts in the respective areas, and submitted draft reports. More than 100 experts related to professional research agencies, insurance industry, banks, and the government contributed to these discussions. Technological options available in the country and abroad were considered by all groups. The Task Force together with the sub-groups then deliberated on key issues and formulated its recommendations as presented in this report. During the discussions it was realised that there were many administrative and institutional issues that needed to be addressed in PMFBY. However, the focus of the Task Force was on its main mandate, technology use in crop insurance. We hope these recommendations would help the Indian crop insurance sector take full advantage of the technological options suggested so as to increase its efficacy and effectiveness leading to reduced agrarian distress in the country