REVIEW PROCESS OF WATER MOVEMENT IN SOIL IN THE SPRINKLER IRRIGATION SYSTEM USING A SIMULATION MODEL HYDRUS-1D

Abstract In the present study, how water moves in soils in the sprinkler irrigation system has been considered

REVIEW PROCESS OF WATER MOVEMENT IN SOIL IN THE SPRINKLER IRRIGATION SYSTEM USING A SIMULATION MODEL HYDRUS-1D

Abstract In the present study, how water moves in soils in the sprinkler irrigation system has been considered

Ancient Gold-Mercury Mining in the Takht-e Soleyman Area, Northwest Iran

The world heritage ancient site of Takht-e Soleyman and its assemblage of metal objects, together with the geological wealth and the  vast ancient mining relics of the Takab area motivated the authors to conduct the investigation that led to this article. The ancient  mining and ore processing sites of the Takht-e Soleyman area were surveyed and investigated in an area of 5000 km2. This contribution introduces briefly the geology and mineral resources together with the traces of ancient mining and ore processing in the area of Takht-e Soleyman. Some archaeological sites were found and documented for the first time during this investigation

Hydrodynamic cavitation on a chip: a tool to detect circulating tumor cells

Circulating tumor cells (CTCs) are essential biomarkers for cancer diagnosis. Although various devices have been designed to detect, enumerate, and isolate CTCs from blood, some of these devices could have some drawbacks, such as the requirement of labeling, long process time, and high cost. Here, we present a microfluidic device based on the concept of "hydrodynamic cavitation-on-chip (HCOC)", which can detect CTCs in the order of minutes. The working principle relies on the difference of the required inlet pressure for cavitation inception of working fluids when they pass through the microfluidic device. The interface among the solid/floating particles, liquid, and vapor phases plays an important role in the strength of the fluid to withstand the rupture and cavitation formation. To this end, four experimental groups, including the "cell culture medium", "medium + Jurkat cells", "medium + Jurkat cells + CTCs", and "medium + CTCs", were tested as a proof of concept with two sets of fabricated microfluidic chips with the same geometrical dimensions, in which one set contained structural sidewall roughness elements. Jurkat cells were used to mimic white blood cells, and MDA-MB-231 cells were spiked into the medium as CTCs. Accordingly, the group with CTCs led to detectable earlier cavitation inception. Additionally, the effect of the CTC concentration on cavitation inception and the effect of the presence of sidewall roughness elements on the earlier inception were evaluated. Furthermore, CTC detection tests were performed with cancer cell lines spiked in blood samples from healthy donors. The results showed that this approach, HCOC, could be a potential approach to detect the presence of CTCs based on cavitation phenomenon and offer a cheap, user-friendly, and rapid tool with no requirement for any biomarker or extensive films acting as a biosensor. This approach also possesses straightforward application procedures to be employed for detection of CTCs

Detergent dissolution intensification via energy-efficient hydrodynamic cavitation reactors

In this study, we explored the potential of hydrodynamic cavitation (HC) for use in dissolution of liquid and powder detergents. For this, microfluidic and polyether ether ketone (PEEK) tube HC reactors with different configurations were employed, and the results from the reactors were compared with a magnetic stirrer, as well as a tergotometer. According to our results PEEK tube HC reactors present the best performance for dissolution of liquid and powder detergents. In the case of liquid detergent, for the same level of initial concentration and comparable final dissolution, the PEEK tube consumed 16.7 and 70% of the energy and time of a tergotometer and 16.7 and 14.8% of that of a magnetic stirrer, respectively. In the case of powder detergent, the PEEK tube used 12% less power than a tergotometer and 81.2% less power than a magnetic stirrer. Additionally, the time required to dissolve the detergent was reduced significantly from 1200 s in the tergotometer and 1800 s in the magnetic stirrer to just 50 s in the PEEK tube. These results suggest that HC could significantly improve the dissolution rate of liquid and powder detergents and energy consumption in washing machines

Fundamentals, biomedical applications and future potential of micro-scale cavitation-a review

Thanks to the developments in the area of microfluidics, the cavitation-on-a-chip concept enabled researchers to control and closely monitor the cavitation phenomenon in micro-scale. In contrast to conventional scale, where cavitation bubbles are hard to be steered and manipulated, lab-on-a-chip devices provide suitable platforms to conduct smart experiments and design reliable devices to carefully harness the collapse energy of cavitation bubbles in different bio-related and industrial applications. However, bubble behavior deviates to some extent when confined to micro-scale geometries in comparison to macro-scale. Therefore, fundamentals of micro-scale cavitation deserve in-depth investigations. In this review, first we discussed the physics and fundamentals of cavitation induced by tension-based as well as energy deposition-based methods within microfluidic devices and discussed the similarities and differences in micro and macro-scale cavitation. We then covered and discussed recent developments in bio-related applications of micro-scale cavitation chips. Lastly, current challenges and future research directions towards the implementation of micro-scale cavitation phenomenon to emerging applications are presented

On the application of hydrodynamic cavitation on a chip in cellular injury and drug delivery

Hydrodynamic cavitation (HC) is a phase change phenomenon, where energy release in a fluid occurs upon the collapse of bubbles, which form due to the low local pressures. During recent years, due to advances in lab-on-a-chip technologies, HC-on-a-chip (HCOC) and its potential applications have attracted considerable interest. Microfluidic devices enable the performance of controlled experiments by enabling spatial control over the cavitation process and by precisely monitoring its evolution. In this study, we propose the adjunctive use of HC to induce distinct zones of cellular injury and enhance the anticancer efficacy of Doxorubicin (DOX). HC caused different regions (lysis, necrosis, permeabilization, and unaffected regions) upon exposure of different cancer and normal cells to HC. Moreover, HC was also applied to the confluent cell monolayer following the DOX treatment. Here, it was shown that the combination of DOX and HC exhibited a more pronounced anticancer activity on cancer cells than DOX alone. The effect of HC on cell permeabilization was also proven by using carbon dots (CDs). Finally, the cell stiffness parameter, which was associated with cell proliferation, migration and metastasis, was investigated with the use of cancer cells and normal cells under HC exposure. The HCOC offers the advantage of creating well-defined zones of bio-responses upon HC exposure simultaneously within minutes, achieving cell lysis and molecular delivery through permeabilization by providing spatial control. In conclusion, micro scale hydrodynamic cavitation proposes a promising alternative to be used to increase the therapeutic efficacy of anticancer drugs