Mefenamic Acid Caplet Stability in Storage Rooms with Different Temperature and Humidity

Mefenamic acid is an unstable drug to light and humidity can cause decomposition. This research aim to get stability data of mefenamic acid stored in West Jakarta health centers as consideration to good drug storage. The research was done by determining 7 health centers using simple random sampling from 74 health centers in West Jakarta, then the drugs depository condition were observed by observation method during 6 months, and the evaluation of mefenamic acid caplet quality were observed by experiment method according to the 4th edition of The Indonesia Pharmacopoeia. The result of this research indicate that five of the depository condition were up to standard, the room temperature of these health centers range 23-29 οC with humidity of 58-67% and mefenamic caplet in those health centers also up to standard during depository 6 months. There were two health centers were the depository room with lam light, no air conditioning and no ventilation, room temperature of 30-35 οC and humidity of 68-70%, in which the color and content of mefenamic acid deteriorated