REVIEW: Carry Me: Animal Babies on the Move

Review of the children\u27s book Carry Me: Animal Babies on the Move, written and illustrated by Susan Stockdale

Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy by Aspelund et al. (2011) Diabetologia 54:2525–2532

published_or_final_versionSpringer Open Choice, 28 May 201

National Assessment of Educational Progress (NAEP) Results: 2019

The National Center for Education Statistics has released this year’s NAEP results which measure nationwide student performance in 4th and 8th grade Reading and Math. NAEP is administered nationally to a representative sample of students from all 50 states, so acts as a standard measure of student performance across states and time. This policy brief will examine Arkansas’ 2019 results and examine score gaps between student groups

Emerging adulthood : exploring the implications for care experienced young people and those who care for them

In this paper, we aim to explore some of the notions and concepts around 'emerging adulthood'; what this might mean for Scotland's care experienced young people; and what this might mean for those who care for them. Societally, transition to adulthood is a longer, more extended process than it was a few decades ago. Young people now generally live longer with their parents who tend to help with ongoing practical and financial support, as well as providing ongoing emotional and relational support and security. Changes in access to secure well-paid employment and to affordable housing and accommodation have been cited as key influencing factors. However, despite recent changes in domestic policy and legislation, too many young people growing up in alternative care – in foster care, residential care and kinship care – continue to experience their transitions from care to adulthood to be accelerated and abrupt. We set the context by exploring some definitions and offering some reflections on the concept of emerging adulthood, and what this might mean for young people transitioning from care to adulthood and interdependence. The challenges faced by our young people, and the need for extended care has become even more amplified as the impacts of the COVID-19 pandemic have hit home - and as the fragility of supports, and the structural disadvantages that many care experienced young people face, have been laid bare

Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

Intestinal epithelial cells exist within a complex environment that affects how they interpret and respond to stimuli. We have applied a multi-scale in vivo systems approach to understand how intestinal immune cells communicate with epithelial cells to regulate responses to inflammatory signals. Multivariate modeling analysis of a large dataset composed of phospho-signals, cytokines, and immune cell populations within the intestine revealed an intimate relationship between immune cells and the epithelial response to TNF-α. Ablation of lymphocytes in the intestine prompted a decrease in the expression of MCP-1, which in turn increased the steady state number of intestinal plasmacytoid dendritic cells (pDCs). This change in the immune compartment affected the intestinal cytokine milieu and subsequent epithelial cell signaling network, with cells becoming hypersensitive to TNF-α-induced apoptosis in a way that could be predicted by mathematical modeling. In summary, we have uncovered a novel cellular network that regulates the response of intestinal epithelial cells to inflammatory stimuli in an in vivo setting

The Grizzly, October 5, 2006

Family Day 2006 Hits Ursinus • Monumental Players in the Black Arts Movement Speak at Ursinus • MSA and Hillel Broke the Fast Together • Free Fitness Class Offered to Ursinus Students • Popping the Pill • Catching Up with Dane Cook • Spotlight on UC Professors: Dr. Bruce Rideout • Abstract Mastery: Exploring the Outdoor Sculpture Collection • Opinions: Forced Suffrage? • Bears Terrorize McDaniel, Ending Nine-Year Streak • Women Split, Men Earn First Conference Pointhttps://digitalcommons.ursinus.edu/grizzlynews/1720/thumbnail.jp

The Grizzly, September 7, 2006

WeCAN Kicks Off the School Year with a Protest for Workers\u27 Rights • Crocodile Hunter Killed by a Stingray • Freshmen Attend First Common Hour • Construction on Campus • Dell Announces Recall • Alternate Energy Sources Needed to Insure Globally-Sound Future • Stopping the Stork: Emergency Contraception • Women, Thou Art Loose: A Concise, Candid Discussion on Sluts, Smuts and Hoes • Opinions: The New Zack\u27s; Dylan Strikes Gold; We Want Water! • Men\u27s Soccer Looking for Breakout Season • Harper and Gibson Carry Bears to Home Opener Victoryhttps://digitalcommons.ursinus.edu/grizzlynews/1716/thumbnail.jp

Cost-analysis of XELOX and FOLFOX4 for treatment of colorectal cancer to assist decision- making on reimbursement

Abstract Background: XELOX (capecitabine + oxaliplatin) and FOLFOX 4 (5-FU + folinic acid + oxaliplatin) have shown similar improvements in survival in patients with metastatic colorectal cancer (MCRC). A US cost-minimization study found that the two regimens had similar costs from a healthcare provider perspective but XELOX had lower costs than FOLFOX4 from a societal perspective, while a Japanese cost-effectiveness study found XELOX had superior cost-effectiveness. This study compared the costs of XELOX and FOLFOX4 in patients with MCRC recently treated in two oncology departments in Hong Kong. Methods: Cost data were collected from the medical records of 60 consecutive patients (30 received XELOX and 30 FOLFOX4) from two hospitals. Drug costs, outpatient visits, hospital days and investigations were recorded and expressed as cost per patient from the healthcare provider perspective. Estimated travel and time costs were included in a societal perspective analysis. All costs were classed as either scheduled (associated with planned chemotherapy and follow-up) or unscheduled (unplanned visits or admissions and associated tests and medicines). Costs were based on government and hospital sources and expressed in US dollars (US$). Results: XELOX patients received an average of 7.3 chemotherapy cycles (of the 8 planned cycles) and FOLFOX4 patients received 9.2 cycles (of the 12 planned cycles). The scheduled cost per patient per cycle was$2,046 for XELOX and $2,152 for FOLFOX4, while the unscheduled cost was$240 and $421, respectively. Total treatment cost per patient was$16,609 for XELOX and $23,672 for FOLFOX4; the total cost for FOLFOX4 was 37$17,836 for XELOX and $27,455 for FOLFOX4. Sensitivity analyses showed XELOX was still less costly than FOLFOX4 when using full drug regimen costs, incorporating data from a US model with costs and adverse event data from their clinical trial and with the removal of oxaliplatin from both treatment arms. Capecitabine would have to cost around four times its present price in Hong Kong for the total resource cost of treatment with XELOX to equal that of FOLFOX4

The Lantern Vol. 76, No. 1, Fall 2008

• Cruel • A Night in Three Parts • The Moment I Said It • To Know • I Will Never Skipskipskip a Rock • The Ravine • Untitled • Skeleton • Midnight Letter • Where Children Come From • Orphan of War • Ciega / Mezquita • The Other Side • Those Dancing Days are Gone • Cycling • The 2nd of July • The Tantric Semantics of Studying Abroad • A Three-Part Study in Musical Relations • Amway Man • Hard Luck Investigator • Spring • Interview With Poet Eleanor Wilnerhttps://digitalcommons.ursinus.edu/lantern/1173/thumbnail.jp

Economic evaluation of the introduction of rotavirus vaccine in Hong Kong.

Background Rotavirus is a common cause of severe gastroenteritis in young children in Hong Kong (HK) with a high economic burden. This study aimed to evaluate the cost-effectiveness of introducing rotavirus vaccination into the HK Government's Childhood Immunisation Programme (CIP) and to include the potential protective effect of the vaccine against seizures. Methods A decision-support model was customised to estimate the potential impact, cost-effectiveness and benefit-risk of rotavirus vaccination in children below 5 years over the period 2020-2029 in HK. Two doses of Rotarix® and three doses of RotaTeq® were each compared to no vaccination. Rotavirus treatment costs were calculated from a governmental health sector perspective (i.e., costs of public sector treatment) and an overall health sector perspective (both governmental and patient, i.e., costs of public sector treatment, private sector treatment, transport and diapers). We ran probabilistic and deterministic uncertainty analyses. Results Introduction of rotavirus vaccination in HK could prevent 49,000 (95% uncertainty interval: ~44,000-54,000) hospitalisations of rotavirus gastroenteritis and seizures and result in ~50 (95% uncertainty interval: ~25-85) intussusception hospitalisations, over the period 2020-2029 (a benefit-risk ratio of ~1000:1), compared to a scenario with no public or private sector vaccine use. The discounted vaccination cost would be US$51-57 million over the period 2020-2029 based on per-course prices of US$72 (Rotarix®) or US$78 (RotaTeq®), but this would be offset by discounted treatment cost savings of US$70 million (government) and US$127 million (governmental and patient health sector). There was a greater than 94% probability that the vaccine could be cost-saving irrespective of the vaccine product or perspective considered. All deterministic 'what-if' scenarios were cost-saving from an overall health sector perspective (governmental and patient). Conclusions Rotavirus vaccination is likely to be cost-saving and have a favourable benefit-risk profile in HK. Based on the assumptions made, our analysis supports its introduction into CIP