262 research outputs found

    Is Phototherapy an Effective Treatment for Herpes Simplex Labialis?

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    Objective: The objective of this evidence based medicine review is to determine if laser phototherapy is an effective treatment for herpes simplex labialis. Study Design: Review of one case study published in 2009, and two randomized controlled trials published in 2010 and 2013. All studies were published in English. Data Source: One case study and two randomized controlled trials were retrieved from PubMed database to write this EBM review Outcomes measured: Decreases in healing time or size based on patient reporting, scoring systems, or photo documentation. Results: The study conducted by Marotti et al determined that the use of laser phototherapy decreases healing time and size of the herpes simplex labialis lesions. In the study by De Carvalho et al, there was a significant difference in monthly average size of the lesions between the groups (p=0.013). The study performed by Dougal et al showed a significant difference in healing time between the groups (p=0.01). Conclusions: Laser phototherapy is an effective and well tolerated treatment for herpes simplex labialis outbreaks

    A New Manuscript of Tiberius Claudius Donatus at UNC-Chapel Hill

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    This thesis presents Folio MS 539 in the Rare Book Collection at Wilson Library, UNC-Chapel Hill, which contains the Interpretationes Vergilianae of Tiberius Claudius Donatus on books 6-12 of the Aeneid. The first chapter describes the manuscript itself from a paleographic perspective and argues for its originating in the region of Veneto in Italy circa 1465. The second chapter collates the text of the manuscript against other known manuscripts and the standard modern edition. The third chapter uses the conclusions of the first two to place the Wilson Library manuscript within the textual transmission of the Interpretationes Vergilianae. The fourth chapter, finally, presents the unique text with which the manuscript opens, accompanied by a commentary, and discusses what this supplement reveals about the treatment of Donatus' work by the humanists who rediscovered it

    A Longitudinal Ultrasound Study of Fetal Growth and Intrauterine Growth Restriction in Kinshasa, Democratic Republic of Congo

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    Each year, 24% of births in resource poor countries are small-for-gestational age (SGA). Most SGA infants suffer from intrauterine growth restriction (IUGR); a pathologic process characterized by insufficient transfer of nutrients and oxygen to the fetus and impaired fetal growth. In resource poor countries, IUGR is frequently due to malaria or maternal under-nutrition. This dissertation addresses clinically important questions concerning the pathogenesis of malaria infection in utero and the identification of IUGR in resource poor settings. The data source is a prospective, longitudinal ultrasound study of 182 pregnant women conducted in Kinshasa, Democratic Republic of Congo between May 2005 and May 2006. Women participated in monthly follow-up visits during which malaria, maternal anthropometrics, and ultrasound estimated fetal weight (EFW) were measured. We estimated the effect of malaria on the risk of IUGR, and assessed whether maternal under-nutrition modified this relationship. Data from 178 women and 758 ultrasounds were included. IUGR was defined as EFW below the 10th percentile of a standardized fetal weight nomogram. Log-binomial models using generalized estimating equations were fitted separately for malaria and maternal anthropometric exposures and including a product interaction term between them. A single incident malaria infection was not significantly associated with IUGR (Risk ratio (RR)=1.2, 95% confidence interval (CI): 0.7, 2.2); women with [greater than or equal to] 3 episodes were at increased risk (RR=2.3, 95% CI: 0.8, 6.3). The effect of malaria was significantly stronger among under-nourished women. Prompt treatment of antenatal malaria infections may prevent IUGR, especially in under-nourished women. We developed a fetal size nomogram for Congo using data from 144 women with certain gestational dates and 755 ultrasound scans. A linear mixed effect model was fitted for EFW as a function of gestational age that incorporated random effects for the intercept and slope. Reference intervals were derived from this model and compared with intervals derived from industrialized countries. The 50th centile EFW for Congo fetuses was consistently lower than fetuses born in industrialized populations. Comparison of the outer centiles showed inconsistent patterns, owing primarily to differing statistical techniques. This fetal size nomogram should improve diagnosis of IUGR in resource poor settings with endemic malaria

    The Clinical Reasoning Assessment Tool for Learning from Standardized Patient Experiences: A Pilot Study

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    Purpose: Clinical reasoning (CR) is the ability to integrate the knowledge of diagnoses with the use of supporting theories to create effective, client-centered interventions. One means of teaching CR to rehabilitation students is using standardized patient (SP) experiences. The relationship between faculty and student CR ratings after SP experiences has not been researched. The purpose of the study was to determine if there would be correlations between physical therapy (PT) and occupational therapy (OT) student and faculty ratings of CR skills after an SP experience. Method: The Clinical Reasoning Assessment Tool (CRAT) was used by students to self-reflect on their CR performance after an SP experience and compared to their respective faculty ratings. The CRAT includes three subsections: content knowledge, procedural knowledge, and conceptual reasoning, each with a visual analog scale. Correlations between students’ self-assessment of CR and faculty reviews were analyzed using Spearman’s rho correlations. Results: Seventeen PT and seventeen OT students participated. Spearman’s rho correlation coefficients for the PT students and their faculty were: content knowledge (r=.180; p=.488), procedural knowledge (r=.697; p=.002), and conceptual reasoning (r=.258; p=.317). Spearman’s rho correlation coefficients for the OT students and their faculty were: content knowledge (r=.103; p=.693), procedural knowledge (r=.676; p=.003), and conceptual reasoning (r=.505; p=.039). Conclusions: Neither PT nor OT student ratings was a statistically significant correlation in content knowledge ratings in relation to respective faculty ratings. Both PT and OT student procedural knowledge rating correlations with faculty were strong and statistically significant. PT student and faculty ratings were not significantly correlated in conceptual reasoning compared to faculty; however, OT students and faculty ratings were strong, had positive correlations, and were statistically significant. Further research is needed to assess students’ CR development longitudinally across curricula

    The Grizzly, August 31, 2006

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    Rebirth of Zack\u27s • Internet Outage on Campus • Changes to Parking on Campus • Class of 2010 Moves In • Sex at Ursinus • Getting to Know Ursinus • Local Dining Delights • Experiencing the Journey • Opinions: Save the Moderates; Opinions Editors Opinions on Opinions; Election Projections • Talent and Experience Lead Bears Into 2006 Season • Field Hockey Looks to Continue Dominance in CChttps://digitalcommons.ursinus.edu/grizzlynews/1715/thumbnail.jp

    Continuing to Confront COPD International Physician Survey: Physician Knowledge and Application of COPD Management Guidelines in 12 Countries

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    AIM: Utilizing data from the Continuing to Confront COPD (chronic obstructive pulmonary disease) International Physician Survey, this study aimed to describe physicians\u27 knowledge and application of the GOLD (Global initiative for chronic Obstructive Lung Disease) Global Strategy for the Diagnosis, Management and Prevention of COPD diagnosis and treatment recommendations and compare performance between primary care physicians (PCPs) and respiratory specialists. MATERIALS AND METHODS: Physicians from 12 countries were sampled from in-country professional databases; 1,307 physicians (PCP to respiratory specialist ratio three to one) who regularly consult with COPD, emphysema, or chronic bronchitis patients were interviewed online, by telephone or face to face. Physicians were questioned about COPD risk factors, prognosis, diagnosis, and treatment, including knowledge and application of the GOLD global strategy using patient scenarios. RESULTS:Physicians reported using spirometry routinely (PCPs 82%, respiratory specialists 100%; P\u3c0.001) to diagnose COPD and frequently included validated patient-reported outcome measures (PCPs 67%, respiratory specialists 81%; P\u3c0.001). Respiratory specialists were more likely than PCPs to report awareness of the GOLD global strategy (93% versus 58%, P\u3c0.001); however, when presented with patient scenarios, they did not always perform better than PCPs with regard to recommending GOLD-concordant treatment options. The proportion of PCPs and respiratory specialists providing first- or second-choice treatment options concordant with GOLD strategy for a GOLD B-type patient was 38% versus 67%, respectively. For GOLD C and D-type patients, the concordant proportions for PCPs and respiratory specialists were 40% versus 38%, and 57% versus 58%, respectively. CONCLUSION: This survey of physicians in 12 countries practicing in the primary care and respiratory specialty settings showed high awareness of COPD-management guidelines. Frequent use of guideline-recommended COPD diagnostic practices was reported; however, gaps in the application of COPD-treatment recommendations were observed, warranting further evaluation to understand potential barriers to adopt guideline recommendations

    The Grizzly, March 22, 2007

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    Speaker on Ethics in the Pharmaceutical Industry • New Plans for the Field House • Potential Carcinogen Found Abundant in Collegeville • WeCAN Button and T-Shirt Campaign Successful • Scientific Sexual Healing • Nutrition Tips: Atkins in the News • Brief History of St. Patrick\u27s Day • Spotlight on Professor Laurian Bowles • Opinions: Obama-mania! • Bears Hungry for CC Crown • Longball Key to Bears Victoryhttps://digitalcommons.ursinus.edu/grizzlynews/1734/thumbnail.jp

    The Grizzly, February 22, 2007

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    Students Join with Local Labor Leaders to Confront Jones Apparel Group • Francophone Film Marathon • Gardasil • WeCAN Strike • New Group Fighting Cancer • The How Article • Spotlight on Dr. Ross Doughty • Nutrition Tips: Stretch it Out! • An Afternoon with Billy Bob Thornton • Opinions: Fixing the Primaries • UC Wrestling Wins Fifth Running CC Championship • Ursinus Senior Flying Through Final Semester with Wngshttps://digitalcommons.ursinus.edu/grizzlynews/1732/thumbnail.jp
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