Characteristics of HIV-infected New Yorkers with ≥2 viral load tests and all persons diagnosed and presumed living, New York City¹.

<p>VL, viral load. NYC, New York City. PLWHA, persons living with HIV/AIDS. MSM, men who have sex with men. IDU, intravenous drug users.</p>1<p>Data as reported to the NYC DOHMH by December 31, 2009.</p>2<p>Includes persons who had heterosexual sex with an HIV-infected person, an injection drug user, or a person who has received blood products. For females only, heterosexual sex also includes sex with a male and at least one of the following: history of commercial sex work, multiple male sex partners, sexually transmitted disease, crack/cocaine use, sex with a bisexual male, probable heterosexual transmission as noted in a medical chart, or negative history of injection drug use.</p>3<p>NYC DOHMH collects race and ethnicity data that meet federal standards of classification and maintains ethnicity data separately from race information. Persons of Hispanic or Latino ethnicity have a separate race classification. Due to small numbers, persons reporting more than one race, Native Americans or Alaska Natives, Hawaiian Natives, Asian, and Pacific Islanders were classified as ‘Other’.</p>4<p>Borough of residence refers to the residence at HIV diagnosis for persons living with HIV (non-AIDS) or residence at AIDS diagnosis for PLWHA.</p

HIV-infected New Yorkers grouped by VL trend, 2006–2007.

<p>HIV-infected New Yorkers grouped by VL trend, 2006–2007.</p

Eligibility flow chart on HIV-infected New Yorkers, 2006 and 2007.

<p>Eligibility flow chart on HIV-infected New Yorkers, 2006 and 2007.</p

Characteristics of HIV-infected New Yorkers with sustained high viral load (SHVL) and durable virologic suppression and all persons diagnosed and presumed living, New York City¹.

<p>VL, viral load. NYC, New York City. PLWHA, persons living with HIV/AIDS. MSM, men who have sex with men. IDU, intravenous drug use. IQR, interquartile range. NA, not available.</p>1<p>Data as reported to the NYC DOHMH by December 31, 2009.</p>2<p>Includes persons who had heterosexual sex with an HIV-infected person, an injection drug user, or a person who has received blood products. For females only, heterosexual sex also includes sex with a male and at least one of the following: history of commercial sex work, multiple male sex partners, sexually transmitted disease, crack/cocaine use, sex with a bisexual male, probable heterosexual transmission as noted in a medical chart, or negative history of injection drug use.</p>3<p>NYC DOHMH collects race and ethnicity data that meet federal standards of classification and maintains ethnicity data separately from race information. Persons of Hispanic or Latino ethnicity have a separate race classification. Due to small numbers, persons reporting more than one race, Native Americans or Alaska Natives, Hawaiian Natives, Asian, and Pacific Islanders were classified as ‘Other’.</p>4<p>Borough of residence refers to the residence at HIV diagnosis for persons living with HIV (non-AIDS) or residence at AIDS diagnosis for PLWHA.</p

STARHS assay results over time among participants with incident HIV in prospective cohort (N = 11).

<p>STARHS assay results over time among participants with incident HIV in prospective cohort (N = 11).</p

Correlation of results on BED-CEIA and AxSYM Avidity Index for recent HIV infection, Cross-sectional sample (N = 190).

<p>Correlation of results on BED-CEIA and AxSYM Avidity Index for recent HIV infection, Cross-sectional sample (N = 190).</p

HIV incidence estimates based on STARHS assays among ARV-naïve, high-risk women in Kigali, Rwanda.

<p>1. Sample-specific window periods, based on data from seroconverter panel.</p><p>2. CD4 adjustment removes individuals with CD4<200 from recent infection classifications: 2 from Concordant; 5 from BED-RI.</p><p>3. False-recent rate calculations exclude individuals taking antiretroviral therapy and with CD4 count <200 cells/µl. Assuming a CoV for the window period of 20%; (CoV for FRR were calculated and input into spreadsheet).</p

Characteristics of cross-sectional survey participants with long-term HIV infection by repeat STARHS test result ≥12 months after HIV diagnosis (N = 141).

<p>Abbreviations: RI = recent infection; LTI = long-term infection.</p>1<p>P-values for the Chi-square or Fisher's exact tests for categorical variables, and the Wilcoxon-Mann-Whitney test for continuous variables.</p>+<p>Includes: recent unexpected weight loss, chronic diarrhea, chronic weakness, fever, cough, night sweats, oral candidiasis.</p

STARHS assay-based incidence estimates, cross-sectional sample.

<p>STARHS assay-based incidence estimates, cross-sectional sample.</p

HIV testing algorithm.

<p>Approximately 800 women at each CRC were tested for HIV infection at screening as indicated. Those confirmed as seronegative and who met the entry criteria (299 at each CRC) were enrolled into the prospective cohort study and retested at 3, 6, 9, and 12 months after enrollment using the same algorithm. Participants who became HIV-positive while on study were referred to available sources of psychosocial and medical care and support. HIV-positive participants could continue on study for scheduled examinations per protocol with the exception of any further HIV testing and genital assessment, unless clinically indicated.</p