Examining the Reliability and Validity of Teacher Candidate Evaluation Instruments

The webinar is designed for faculty and staff of educator preparation programs (EPPs), state education agency (SEA) staff responsible for oversight of teacher preparation and certification, and others interested in the evaluation of teacher candidates. The content of the webinar will focus on the Council for the Accreditation of Educator Preparation (CAEP) program standards that require that EPPs use evaluation instruments with evidence of reliability and validity. The content will also include two studies that examined the reliability and validity of a teacher candidate evaluation instrument

Integrated modeling and simulation of lunar exploration campaign logistics

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2007.Includes bibliographical references (p. 138-140).As NASA prepares to establish a manned outpost on the lunar surface, it is essential to consider the logistics of both the construction and operation of this outpost. This thesis presents an interplanetary supply chain management and logistics planning and simulation software tool, SpaceNet, developed to assist mission architects, planners, systems engineers and logisticians in performing analysis on what will be needed to support future human exploration missions, primarily in the Earth-Moon-Mars system. Also presented in this thesis are the results of numerous trade studies performed using SpaceNet to determining the best mix of mission types (pre-positioning, carry-along and resupply) to achieve sustainable, robust space exploration. These trade studies focus on analyzing notional mission architectures in terms of scientific benefit, logistical overhead and robustness to campaign level risks such as flight delays, flight cancellations and uncertain demand parameters. The significant findings presented in this thesis broadly fall into three categories: a demonstration of the value of integrated modeling and simulation of campaign logistics, the best logistics strategy for the establishment of a lunar outpost, and suggestions to reduce campaign level risk.(cont.) The development of SpaceNet has made several key contributions to the field of space logistics, primarily in the creation of a set of ten function-based classes of supply for human space exploration, the detailed modeling of demand parameters at the supply class level, and the ability to model entire campaigns of missions and to compare these campaigns using the measures of effectiveness developed. Through the campaign analysis it is shown that the Lunar Architecture Team (LAT) Option 1 lunar mission architecture is ~11,500 kg short of being able to support four crew members for the proposed durations. It is also shown that the inclusion of at least two unmanned cargo missions makes the architecture sustainable. The campaign level risk analysis research performed demonstrates that the best way to protect against schedule and demand uncertainty is to maintain at least a 90-day safety stock of consumables at the lunar base (~2100 kg for a crew of four).by Sarah A. Shull.S.M

Mapping the Nephron Exercise Incorporates Multiple Learning Strategies

Introduction: Understanding the location and action of nephron transporters and channels is important to the understanding of renal function. As each region of the nephron is unique in its inclusion of specific transporters and channels, mapping of the nephron is an effective first step in understanding overall nephron processing. We describe a small-group, active-learning exercise that facilitates students' ability to understand renal processing within each region of the nephron. Methods: Following an overview lecture on renal transporters and channels, small groups of students worked cooperatively to map the nephron. This 2-hour, collaborative exercise was developed to reinforce key concepts in renal processing of ions and nutrients and, at the same time, utilize effective learning strategies. Learning strategies incorporated in this exercise include small-group collaboration, peer teaching, retrieval practice using an audience response system, and elaboration through discussion. Results: Written examination was used to assess student understanding. Students demonstrated higher performance on a subset of questions related to this learning activity compared to the overall exam. Highly positive feedback was provided by a convenience sample of students completing an anonymous survey. Discussion: This nephron-mapping exercise was an effective means to promote synthesis and analysis of lecture content and engage students in methods that enhance learning

Application of Structured Decision Making to Wildlife Management in Montana

Good decision-making is essential to conserving wildlife populations. Whereas there may be multiple ways to address a problem, perfect solutions rarely exist. Managers are therefore tasked with identifying optimal decisions that will best achieve desired outcomes. Structured decision making (SDM) is a method of decision analysis used to identify the most effective, efficient, and realistic optimal decisions while accounting for values and priorities of the decision maker. The stepwise process includes identifying the management problem, defining objectives for solving the problem, developing alternative approaches to achieve the objectives, and formally evaluating which alternative is most likely to accomplish the objectives. The SDM process can be more effective than informal decision-making because it provides a transparent way to quantitatively evaluate decisions for addressing multiple management objectives while incorporating science, uncertainty, and risk tolerance. We illustrate the application of this process to management needs, including an SDM-based decision tool developed to identify optimal decisions for proactively managing risk of pneumonia epizootics in bighorn sheep (Ovis canadensis). Pneumonia epizootics are a major challenge for managers, including in terms of knowing how or when to manage risk. The decision tool facilitates analysis of alternative decisions for how to manage herds based on predictions from a risk model, herd-specific objectives, and predicted costs and benefits of each alternative. Managers can be confident resulting decisions are most effective, efficient, and realistic because they explicitly account for important considerations managers implicitly weigh when making decisions, including competing management objectives, uncertainty in potential outcomes and risk tolerance

Individual differences in susceptibility to false memories: The effect of memory specificity

Previous research has highlighted the wide individual variability in susceptibility to the false memories produced by the Deese/Roediger-McDermott (DRM) procedure [Deese, J. (1959). On the prediction of occurrence of particular verbal intrusions in immediate recall. Journal of Experimental Psychology, 58, 17–22; Roediger, H. L., III, & McDermott, K. B. (1995). Creating false memories: Remembering words not presented in lists. Journal of Experimental Psychology: Learning, Memory, & Cognition, 21, 803–814]. The current study investigated whether susceptibility to false memories is influenced by individual differences in the specificity of autobiographical memory retrieval. Memory specificity was measured using the Sentence Completion for Events from the Past Test (SCEPT) [Raes, F., Hermans, D., Williams, J. M. G., & Eelen, P. (2007). A sentence completion procedure as an alternative to the Autobiographical Memory Test for assessing overgeneral memory in non-clinical populations. Memory, 15, 495-507]. Memory specificity did not correlate with correct recognition, but a specific retrieval style was positively correlated with levels of false recognition. It is proposed that the contextual details that frequently accompany false memories of nonstudied lures are more accessible in individuals with specific retrieval styles

A role for human mitochondrial complex II in the production of reactive oxygen species in human skin

AbstractThe mitochondrial respiratory chain is a major generator of cellular oxidative stress, thought to be an underlying cause of the carcinogenic and ageing process in many tissues including skin. Previous studies of the relative contributions of the respiratory chain (RC) complexes I, II and III towards production of reactive oxygen species (ROS) have focussed on rat tissues and certainly not on human skin which is surprising as this tissue is regularly exposed to UVA in sunlight, a potent generator of cellular oxidative stress. In a novel approach we have used an array of established specific metabolic inhibitors and DHR123 fluorescence to study the relative roles of the mitochondrial RC complexes in cellular ROS production in 2 types of human skin cells. These include additional enhancement of ROS production by exposure to physiological levels of UVA. The effects within epidermal and dermal derived skin cells are compared to other tissue cell types as well as those harbouring a compromised mitochondrial status (Rho-zero A549). The results show that the complex II inhibitor, TTFA, was the only RC inhibitor to significantly increase UVA-induced ROS production in both skin cell types (P<0.05) suggesting that the role of human skin complex II in terms of influencing ROS production is more important than previously thought particularly in comparison to liver cells. Interestingly, two-fold greater maximal activity of complex II enzyme was observed in both skin cell types compared to liver (P<0.001). The activities of RC enzymes appear to decrease with increasing age and telomere length is correlated with ageing. Our study showed that the level of maximal complex II activity was higher in the MRC5/hTERT (human lung fibroblasts transfected with telomerase) cells than the corresponding wild type cells (P=0.0012) which can be considered (in terms of telomerase activity) as models of younger and older cells respectively