Synthesis of Pd+2 complexes of Schiff bases containing methyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate and spectral and catalytic activities

Here in, ONS-donor atom containing Schiff base ligands (1, 2) was used to prepare 1a and 2a complexes. The Schiff base ligands were synthesized using 2?hydroxy-3-methoxysalicylaldehyde and 4-benzoxybenzaldehyde with methyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate as precursors in ethanol medium. Pd(II) complexes (1a, 2a) were prepared using the corresponding PdCl2(CH3CN)2 and Schiff base in a (1:1) molar proportion. The Schiff bases (1, 2) and their Pd(II) complexes (1a, 2a) were then identified via various analytical/spectroscopic methods (1H and 13C) NMR, UV- Vis spectra, FT-IR, mass, TGA and CHN to determine their molecular structures. Finally, the results obtained based on Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions show that electron-donating and electron-withdrawing substituents on the aryl halide might produce coupling products in excellent yield in the presence of 1a, 2a complexes (as catalysts) under optimum conditions. © 2022Muş Alparslan Üniversitesi: BAP-20-TBMY-4902–03This study was supported by Muş Alparslan University (Turkey) Research Fund (BAP-20-TBMY-4902–03). The authors thank the Institute of Science for their postgraduate studies and the Department of Chemistry of the Faculty of Arts and Sciences of Muş Alparslan University for the characterization of the compounds (FT-IR and UV-Vis Spectrophotometer analysis).This study was supported by Muş Alparslan University (Turkey) Research Fund (BAP-20-TBMY-4902–03). The authors thank the Institute of Science for their postgraduate studies and the Department of Chemistry of the Faculty of Arts and Sciences of Muş Alparslan University for the characterization of the compounds (FT-IR and UV-Vis Spectrophotometer analysis)