Neutrophil gelatinase-associated lipocalin (NGAL) circulating levels are related to LDL Myocardial infarction

Background: Low-density lipoprotein receptors (LDL-R) in hepatocytes are degraded by the enzyme Neiutrophophil gielatinase-associated lipocalin (NGAL) A brand-new target for lipid-lowering treatment is Neiutrophophil gielatinase-associated lipocalin (NGAL) inhibition. Three subsets of monocytes, which play a critical role in the pathophysiology of atherosclerosis, are known. Objectives: The aim of this study was to examine whether circulating levels of Neiutrophophil gielatinase-associated lipocalin (NGAL) are associated with LDL liped subsets. Materials and Methods: We included 70 patients with coronary artery disease. Neiutrophophil gielatinase-associated lipocalin (NGAL) levels were measured and LDL liped and 30 control health. Results: Eighty percent of the patients were men, with a mean age between 40 and 70. Patients increese displayed greater Neiutrophophil gielatinase-associated lipocalin (NGAL) -levels compared to the 30 male control group. Neiutrophophil gielatinase-associated lipocalin (NGAL) levels in the blood were associated with CM treatment in patients, whereas NCM had the opposite effect. Patients whose levels of Neiutrophophil gielatinase-associated lipocalin (NGAL) were greater than the median displayed a significantly higher. Conclusions: Endurance training, resistance training, and combined training improve cardiovascular risk factors associated with obesity. These types of training methods also improve cardiovascular risk factors in school obese children. Also, they can be used as effective exercise programs for these people. Therefore, EET, RET, and CET used in this study, especially EET, can be recommended as a non-medical way to improve the incidence of cardiovascular risk factors and obesity-related disorders in obese boys

Cytotoxic Effect of Vincarosea Aqueous Crude Extraction Human Brain Carcinoma Cell Line (AMGM) In Vitro

The present study investigated the cytotoxic effects of aqueous crude extracts of Vincarosea leaves, flowers and seeds on Human brain carcinoma cell line (AMGA, Ahmed Majeed Glioblastoma Multiform ) in vitro, by using serial double dilution (concentration between 1.95-1000 µg/ml). The results showed that the cytotoxic effect of extracts was depended on type of parts of plant extracted, concentration and exposure time. The concentration 1000 µg/ml gave inhibition rate (IR), were (34, 49 and 64) % of leaves, flowers and seeds extracts respectively compared with control 100% after 24 hours from exposure time. However, low concentrations of aqueous extracts were found to induce the AMGA cells growth and proliferation (PR), it was 115% by treatment with aqueous extract offlowers extract in 1.95 µg/ml after 24 hours of exposed

Cytotoxic Effect of the Crude Alcoholic Extract of Juncus Rigidus on Cells of the Human Breast Cancer Line MCF-7 in Vitro

This study tested the toxicological activity of the crude alcoholic extract of the vegetative part of Juncus rigidus on cells of the MCF-7. The quantitative estimation of the active compounds of the alcoholic extract (alkaloids - tannins - flavonoids - phenols) was found, as the results gave (6.06 - 7.91 - 13.84 - 16.34 mg/g) respectively. The antioxidant activity of the alcoholic extract was also calculated by DPPH method. The percentages of free radical inhibition were (9.31%, 16.43%, 19.81%,20.51%,24.31%) at concentrations (10,20,30,40,50 mg/ml) respectively. Six concentrations of (6.25, 12.5, 25, 50, 100, 200 μg/ml) of alcoholic extract of the vegetative part of the plant were tested on the growth of human breast cancer cells MCF-7 line for ( 3 ) exposure periods (24,48,72) Hr .Where the extract had a toxic effect on cell growth from the lowest used concentration (6.25 μg/ml), where the inhibition percentage was recorded (2±32.8%) for the 72-hour exposure period and for a probability level (P≤ 0.05) versus (72.3%±2) at the concentration (200 µg/ml) and for the same exposure time and probability level

The cytotoxicity effect of crude aqueous and alcoholic extracts of Juncus rigidus on human lung cancer cell line (A549) in vitro

The current study dealt with the identification on cytotoxicity effective of crude water and alcohol extracts from the  Juncus rigidus on human lung cancer cells A549. The quantitative estimation of the active compounds of the water and alcohol extracts of the Juncus (Phenols - Flavonoids - Alkaloids - Tannins) was calculated The results of the aqueous extract were (8.82,5.91,13.42,16.29) mg/g, respectively. While the results of the crude alcoholic extract of the plant were (7.01,6.06,13.84,16.34) mg/g, respectively. The cytotoxicity effect of the water and alcohol  extracts of the plant  was tested on human lung cancer cells A549 and took six concentrations (200,100,50,25,12.5,6.25)micrograms/millilters for 3 exposing times(72, 48, 24)Hr, which recorded  highest inhibition rate was for the alcoholic extract of the plant at a concentration (200) µg/ml, for an exposure period (72) hours, and for a probability level (0.05) that reached (83.45%), while (IR) of cancer cells obtained from the aqueous extract was recorded (68.96%)

Cytotoxic effect of the crude alcoholic extract of Juncus rigidus on cells of the human breast cancer line MCF-7 in vitro

This study tested the toxicological activity of the crude alcoholic extract of the vegetative part of Juncus rigidus on cells of the MCF-7. The quantitative estimation of the active compounds of the alcoholic extract (alkaloids - tannins - flavonoids - phenols) was found, as the results gave (6.06 - 7.91 - 13.84 - 16.34 mg/g) respectively. The antioxidant activity of the alcoholic extract was also calculated by DPPH method. The percentages of free radical inhibition were (9.31%, 16.43%, 19.81%,20.51%,24.31%) at concentrations (10,20,30,40,50 mg/ml) respectively. Six concentrations of (6.25, 12.5, 25, 50, 100, 200 μg/ml) of alcoholic extract of the vegetative part of the plant were tested on the growth of human breast cancer cells MCF-7 line for ( 3 ) exposure periods (24,48,72) Hr .Where the extract had a toxic effect on cell growth from the lowest used concentration (6.25 μg/ml), where the inhibition percentage was recorded (2±32.8%) for the 72-hour exposure period and for a probability level (P≤ 0.05) versus (72.3%±2) at the concentration (200 µg/ml) and for the same exposure time and probability level