Drugs and afterparties.

Graham Ryall of the Rialto Community Drug Team and Dr Kiran Santlal, a Registrar in Psychiatry of Substance Misuse in the HSE National Drug Treatment Centre, speak about the rise of Crystal Meth and GHB use on the afterparty scene

Gamma Hydroxybutyrate & Gamma Butrolactone (GHB/GBL): a case series of inpatient & outpatient detoxification.

GHB is a natural endogenous neurotransmitter. It can also be ingested orally and crosses the blood-brain barrier. It is structurally similar to gamma-aminobutyric acid (GABA) and acts on GABA & GHB receptors in brain with effects on the dopaminergic system. It is rapidly eliminated and not detectable after: 4 hours in the blood 12 hours in the urine. This poster includes: Symptoms of GHB overdose and withdrawal, Management of GHB overdose and withdrawal, Treatment episodes & outcomes in the GHB clinic

Changes in first-time registration for opioid agonist treatment in Ireland between 1999 and 2019

To improve the understanding of problematic opioid use, monitoring of patterns of use is essential. We investigated changes in first-time registrations for opioid agonist treatment (OAT) in Ireland from 1999 to 2019. Data on individuals aged 15–64 years registering for OAT in Ireland for the first time from 1999 to 2019 were retrieved from the Central Treatment List, the database of all individuals receiving OAT in Ireland. Secular changes in numbers and rates of first-time registrations by age and sex were analyzed. The overall incidence of first-time treatments for opioid use decreased from 40.7 per 100,000 in 1999 to 23.0 per 100,000 in 2019 (p  The trends observed indicate a sustained decline in opioid use disorder in Ireland in younger individuals. These favorable findings support the view that recent drug policy in Ireland has contributed in part to the decline in heroin use among this group.</p