Low temperature microwave emission from molecular clusters

We investigate the experimental detection of the electromagnetic radiation generated in the fast magnetization reversal in Mn12-acetate at low temperatures. In our experiments we used large single crystals and assemblies of several small single crystals of Mn12-acetate placed inside a cylindrical stainless steel waveguide in which an InSb hot electron device was also placed to detect the radiation. All this was set inside a SQUID magnetometer that allowed to change the magnetic field and measure the magnetic moment and the temperature of the sample as the InSb detected simultaneously the radiation emitted from the molecular magnets. Our data show a sequential process in which the fast inversion of the magnetic moment first occurs, then the radiation is detected by the InSb device, and finally the temperature of the sample increases during 15 ms to subsequently recover its original value in several hundreds of milliseconds.Comment: changed conten

Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes

CD38 controls the chemotaxis of leukocytes to some, but not all, chemokines, suggesting that chemokine receptor signaling in leukocytes is more diverse than previously appreciated. To determine the basis for this signaling heterogeneity, we examined the chemokine receptors that signal in a CD38-dependent manner and identified a novel "alternative" chemokine receptor signaling pathway. Similar to the "classical" signaling pathway, the alternative chemokine receptor pathway is activated by G{alpha}i2-containing Gi proteins. However, unlike the classical pathway, the alternative pathway is also dependent on the Gq class of G proteins. We show that G{alpha}q-deficient neutrophils and dendritic cells (DCs) make defective calcium and chemotactic responses upon stimulation with N-formyl methionyl leucyl phenylalanine and CC chemokine ligand (CCL) 3 (neutrophils), or upon stimulation with CCL2, CCL19, CCL21, and CXC chemokine ligand (CXCL) 12 (DCs). In contrast, G{alpha}q-deficient T cell responses to CXCL12 and CCL19 remain intact. Thus, the alternative chemokine receptor pathway controls the migration of only a subset of cells. Regardless, the novel alternative chemokine receptor signaling pathway appears to be critically important for the initiation of inflammatory responses, as G{alpha}q is required for the migration of DCs from the skin to draining lymph nodes after fluorescein isothiocyanate sensitization and the emigration of monocytes from the bone marrow into inflamed skin after contact sensitization

The ultracool dwarf DENIS-P J104814.7-395606. Chromospheres and coronae at the low-mass end of the main-sequence

We have obtained an XMM-Newton observation and a broad-band spectrum from the ultraviolet to the near infrared with X-Shooter for one of the nearest M9 dwarfs, DENIS-P J1048-3956 (4pc). We integrate these data by a compilation of activity parameters for ultracool dwarfs from the literature with the aim to advance our understanding of these objects by comparing them to early-M type dwarf stars and the Sun. Our deep XMM-Newton observation has led to the first X-ray detection of DENIS-P J1048-3956 (log Lx = 25.1) as well as the first measurement of its V band brightness (V = 17.35mag). Flux-flux relations between X-ray and chromospheric activity indicators are here for the first time extended into the regime of the ultracool dwarfs. The approximate agreement of DENIS-P J1048-3956 and other ultracool dwarfs with flux-flux relations for early-M dwarfs suggests that the same heating mechanisms work in the atmospheres of ultracool dwarfs, albeit weaker as judged from their lower fluxes. The observed Balmer decrements of DENIS-P J1048-3956 are compatible with optically thick plasma in LTE at low, nearly photospheric temperature or optically thin LTE plasma at 20000K. Describing the decrements with CaseB recombination requires different emitting regions for Halpha and the higher Balmer lines. The high observed Halpha/Hbeta flux ratio is also poorly fitted by the optically thin models. We derive a similarly high value for the Halpha/Hbeta ratio of vB10 and LHS2065 and conclude that this may be a characteristic of ultracool dwarfs. We add DENIS-P J1048-3956 to the list of ultracool dwarfs detected in both the radio and the X-ray band. The Benz-Guedel relation between radio and X-ray luminosity of late-type stars is well-known to be violated by ultracool dwarfs. We speculate on the presence of two types of ultracool dwarfs with distinct radio and X-ray behavior.Comment: accepted for publication in Astronomy & Astrophysic

Sintomas de deficiências de macronutrientes em plantas de jaborandi (Pilocarpus microphyllus Starf.).

bitstream/item/57703/1/CPATU-ComTec84.pd

El deber legal de conservación, la ITE y el IEE: nuevos instrumentos normativos para el impulso de la conservación y la rehabilitación edificatoria

This paper presents the results of the comparative analysis of the national, regional and local regulatory frameworks related to the legal duty of conservation, the Buildings’ Technical Inspection (ITE) and the Buildings´ Assessment Report (IEE). Although it confirms that these instruments have been widely assumed in Spain, and that they no longer only include the assessment of the conservation status, but also of buildings’ accessibility and energy efficiency, there is still a certain conceptual gap to be filled in order to articulate them correctly with the current contents of the legal conservation duty and with the terminology of the LOE and the CTE, as well as to understand their role in the promotion, beyond the strict conservation, of the voluntary upgrading of the Spanish existing housing stock.Este trabajo presenta los resultados del análisis comparado de la normativa estatal y autonómica, así como de las ordenanzas municipales, relacionadas con el deber legal de conservación, la Inspección Técnica (ITE) y el Informe de Evaluación de Edificios (IEE). Aunque se constata que, en los últimos años, se han generalizado estos instrumentos y que ya no solamente comprenden la evaluación del estado de conservación, sino también de la accesibilidad y la eficiencia energética, todavía falta un cierto recorrido conceptual para terminarlos de articular correctamente con los contenidos actuales del deber de conservación, la LOE y el CTE, así como para que estos instrumentos puedan impulsar realmente, más allá de la estricta conservación, la mejora de la calidad del parque edificado residencial español

Simian immunodeficiency virus infection in wild-caught chimpanzees from Cameroon

Simian immunodeficiency viruses (SIVcpz) infecting chimpanzees (Pan troglodytes) in west central Africa are the closest relatives to all major variants of human immunodeficiency virus type 1 ([HIV-1]; groups M, N and O), and have thus been implicated as the source of the human infections; however, information concerning the prevalence, geographic distribution, and subspecies association of SIVcpz still remains limited. In this study, we tested 71 wild-caught chimpanzees from Cameroon for evidence of SIVcpz infection. Thirty-nine of these were of the central subspecies (Pan troglodytes troglodytes), and 32 were of the Nigerian subspecies (Pan troglodytes vellerosus), as determined by mitochondrial DNA analysis. Serological analysis determined that one P. t. troglodytes ape (CAM13) harbored serum antibodies that cross-reacted strongly with HIV-1 antigens; all other apes were seronegative. To characterize the newly identified virus, 14 partially overlapping viral fragments were amplified from fecal virion RNA and concatenated to yield a complete SIVcpz genome (9,284 bp). Phylogenetic analyses revealed that SIVcpzCAM13 fell well within the radiation of the SIVcpzPtt group of viruses, as part of a clade including all other SIVcpzPtt strains as well as HIV-1 groups M and N. However, SIVcpzCAM13 clustered most closely with SIVcpzGAB1 from Gabon rather than with SIVcpzCAM3 and SIVcpzCAM5 from Cameroon, indicating the existence of divergent SIVcpzPtt lineages within the same geographic region. These data, together with evidence of recombination among ancestral SIVcpzPtt lineages, indicate long-standing endemic infection of central chimpanzees and reaffirm a west central African origin of HIV-1. Whether P. t. vellerosus apes are naturally infected with SIVcpz requires further study

Non-thermal emission in hyper-velocity and semi-relativistic stars

Context. There is a population of runaway stars that move at extremely high speeds with respect to their surroundings. The fast motion and the stellar wind of these stars, plus the wind-medium interaction, can lead to particle acceleration and non-thermal radiation. Aims. We characterise the interaction between the winds of fast runaway stars and their environment, in particular to establish their potential as cosmic-ray accelerators and non-thermal emitters. Methods. We model the hydrodynamics of the interaction between the stellar wind and the surrounding material. We self-consistently calculate the injection and transport of relativistic particles in the bow shock using a multi-zone code, and compute their broadband emission from radio to γ-rays. Results. Both the forward and reverse shocks are favourable sites for particle acceleration, although the radiative efficiency of particles is low and therefore the expected fluxes are in general rather faint. Conclusions. We show that high-sensitivity observations in the radio band can be used to detect the non-thermal radiation associated with bow shocks from hyper-velocity and semi-relativistic stars. Hyper-velocity stars are expected to be modest sources of sub-TeV cosmic rays, accounting perhaps for ∼0.1% of that of galactic cosmic rays