3 research outputs found

    <i>n</i>‑BuLi/LiCH<sub>2</sub>CN-Mediated One-Carbon Homologation of Aryl Epoxides into Conjugated Allyl Alcohols

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    A series of styrene oxides in the presence of a 1:1 mixture of <i>n-</i>butyllithium (<i>n</i>-BuLi) and lithioacetonitrile (LiCH<sub>2</sub>CN) in THF are converted into one-carbon homologated allyl alcohols in an unusual regioselective manner
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