Surface-Enhanced Raman Spectroscopy (SERS) Based on ZnO Nanorods for Biological Applications

Detection of nanometer-sized biomarkers is a research topic that attracts much attention as an application for early diagnosis of diseases. Biopsy monitoring by analyzing cell secretion in a non-destructive way has many advantages in the field of biomedicine. We introduce the Raman signal enhancement method on a biosensing chip based on surface-enhanced Raman diagnosis. This approach has the advantage because the ZnO nanorods are grown to form nanoscale porosity and are coated with gold to enable size selective biomarker detection. After sputtering gold on the grown ZnO nanostructures, the unique feature of clustering the nanorod’s heads first appeared. The grain formation on the head was the main factor for the localized surface plasmon resonance (LSPR) enhancement, and this fact could be verified by finite element analysis. It has been demonstrated in breast cancer cell line that the cell viability is also high in such gold-clad ZnO nanostructure-based surface-enhanced substrates. For bioapplication, interstitial cystitis/bladder pain syndrome (IC/BPS) animal model was prepared by injecting HCl into the bladder of a rat, and urine was collected a week later to conduct Raman spectroscopy experiments

知的資産会計の体系化

This study concerns for the systematization of accounting for Intellectual Assets, closely examining a reasonable accounting policy to measure and disclose a class of productive resources, which can be christened as the Intellectual assets. I will show a kind of ones as technique for systematization of accounting for Intel-lectual Assets as follows. Firstly, giving to definition it by conceptual regulations of Intellectual Assets. Secondly, rationalizing it by method to measure and a basis of measurement for the Intellectual Assets. Finally, rationalizing it by system of Intel-lectual Assets management, and so far

環境会計情報の質的確保に関する一考察

This thesis concerns several techniques for the qualitative preservation of environmental accounting information, closely examining the essential sense of relevance and the reliability that are one of the qualitative characteristics determining for the usefulness of environmental information. It shows following kind of ones as technique for the qualitative preservation of environmental accounting information. Firstly, preserving it by synthetic environmental accounting system. Secondly, regulating it by inclusive environmental accounting standard. Finally, guaranteeing it by environmental auditing, and so far