Spacetime structure of 5D hypercylindrical vacuum solutions with tension

We investigate geometrical properties of 5D cylindrical vacuum solutions with a transverse spherical symmetry. The metric is uniform along the fifth direction and characterized by tension and mass densities. The solutions are classified by the tension-to-mass ratio. One particular example is the well-known Schwarzschild black string which has a curvature singularity enclosed by a horizon. We focus mainly on geometry of other solutions which possess a naked singularity. The light signal emitted by an object approaching the singularity reaches a distant observer with finite time, but is infinitely red-shifted.Comment: revtex4, 5 pages, 2 figures. To appear in the proceedings of the 10th Asia Pacific Physics Conference (APPC10), Pohang, Korea, 21-24 Aug. 2007. Submitted to J. Korean Phys. Soc. Penrose diagram has been adde

Highly sensitive colorimetric detection of allergies based on an immunoassay using peroxidase-mimicking nanozymes

Nanomaterials that exhibit enzyme-like characteristics, which are called nanozymes, have recently attracted significant attention due to their potential to overcome the intrinsic limitations of natural enzymes, such as low stability and relatively high cost for preparation and purification. In this study, we report a highly efficient colorimetric allergy detection system based on an immunoassay utilizing the peroxidase- mimicking activity of hierarchically structured platinum nanoparticles (H-Pt NPs). The H-Pt NPs had a diameter of 30 nm, and were synthesized by a seed-mediated growth method, which led to a significant amount of peroxidase-like activity. This activity mainly occurs because of the high catalytic power of the Pt element, and the fact that the H-Pt NPs have a large surface area available for catalytic events. The H-Pt NPs were conjugated to an antibody for the detection of immunoglobulin E (IgE) in the analytes; IgE is a representative marker for the diagnosis of allergies. They were then successfully integrated into a conventionally used allergy diagnostic test, the ImmunoCAP diagnostic test, as a replacement for natural signaling enzymes. Using this strategy, total and specific IgE levels were detected within 5 min at room temperature, with high specificity and sensitivity. The practical utility of the immunoassay was also successfully verified by correctly determining the levels of both total and specific IgE in real human serum samples with high precision and reproducibility. The present H-Pt NP-based immunoassay system would serve as a platform for rapid, robust, and convenient analysis of IgE, and can be extended to the construction of diagnostic systems for a variety of clinically important target molecules.11Ysciescopu

Schwinger Pair Production at Finite Temperature in Scalar QED

In scalar QED we study the Schwinger pair production from an initial ensemble of charged bosons when an electric field is turned on for a finite period together with or without a constant magnetic field. The scalar QED Hamiltonian depends on time through the electric field, which causes the initial ensemble of bosons to evolve out of equilibrium. Using the Liouville-von Neumann method for the density operator and quantum states for each momentum mode, we calculate the Schwinger pair-production rate at finite temperature, which is the pair-production rate from the vacuum times a thermal factor of the Bose-Einstein distribution.Comment: RevTex 10 pages, no figure; replaced by the version accepted in Phys. Rev. D; references correcte

The cortical activation pattern by a rehabilitation robotic hand: a functional NIRS study

Introduction: Clarification of the relationship between external stimuli and brain response has been an important topic in neuroscience and brain rehabilitation. In the current study, using functional near infrared spectroscopy (fNIRS), we attempted to investigate cortical activation patterns generated during execution of a rehabilitation robotic hand. Methods: Ten normal subjects were recruited for this study. Passive movements of the right fingers were performed using a rehabilitation robotic hand at a frequency of 0.5 Hz. We measured values of oxy-hemoglobin (HbO), deoxy-hemoglobin (HbR) and total-hemoglobin (HbT) in five regions of interest: the primary sensory-motor cortex (SM1), hand somatotopy of the contralateral SM1, supplementary motor area (SMA), premotor cortex (PMC), and prefrontal cortex (PFC). Results: HbO and HbT values indicated significant activation in the left SM1, left SMA, left PMC, and left PFC during execution of the rehabilitation robotic hand (uncorrected, p < 0.01). By contrast, HbR value indicated significant activation only in the hand somatotopic area of the left SM1 (uncorrected, p < 0.01). Conclusions: Our results appear to indicate that execution of the rehabilitation robotic hand could induce cortical activation. © 2014 Chang, Lee, Gu, Lee, Jin, Yeo, Seo and Jang.1

Nonperturbative QED Effective Action at Finite Temperature

We advance a novel method for the finite-temperature effective action for nonequilibrium quantum fields and find the QED effective action in time-dependent electric fields, where charged pairs evolve out of equilibrium. The imaginary part of the effective action consists of thermal loops of the Fermi-Dirac or Bose-Einstein distribution for the initial thermal ensemble weighted with factors for vacuum fluctuations. And the real part of the effective action is determined by the mean number of produced pairs, vacuum polarization, and thermal distribution. The mean number of produced pairs is equal to twice the imaginary part. We explicitly find the finite-temperature effective action in a constant electric field.Comment: RevTex4, 6pages, no figure; replaced by the version to be published in Phys. Rev.

Gastroprotective effects of the isopropanol extract of Artemisia princeps and its gastroretentive floating tablets on gastric mucosal injury

In this study, we investigated the gastroprotective effect of an isopropanol extract from the aerial parts of Artemisia princeps (IPAP) and developed a gastroretentive floating tablet of IPAP (IPAP-FR) for maximized local gastroprotective effects. Pre-treatment with IPAP ameliorated the gastric mucosal hemorrhagic lesions in ethanol/HCl- or indomethacin-treated rats. IPAP decreased mucosal hemorrhage of gastric ulcers induced by ethanol or indomethacin plus pyloric ligation in rats. The optimized floating tablet, IPAP-FR, floated on medium surface with more sustained eupatilin release compared to the non-floating control tablet. X-ray photographs in beagle dogs showed that IPAP-FR was retained for >2 h in the stomach. In the ethanol-induced gastric ulcer rat model, the gastric hemorrhagic lesion was improved more substantially with IPAP-FR compared to the non-floating control tablet. Based on these data, our data suggest that IPAP-FR has an improved therapeutic potential for the treatment of gastric ulcer

Effective Action of QED in Electric Field Backgrounds II: Spatially Localized Fields

We find the Bogoliubov coefficient from the tunneling boundary condition on a charged particle coupled to a static electric field $E_0 sech^2 (z/L)$ and, using the regularization scheme in Phys. Rev. D 78, 105013 (2008), obtain the exact one-loop effective action in scalar and spinor QED. It is shown that the effective action satisfies the general relation between the vacuum persistence and the mean number of produced pairs. We advance an approximation method for general electric fields and show the duality between the space-dependent and time-dependent electric fields of the same form at the leading order of the effective actions.Comment: RevTex 7 pages, no figure; extension of arXiv:0807.2696 to space-dependent electric fields; new section added on approximate effective actions in general electric fields and conclusion shortened; references added; replaced by the version to be published in Phys. Rev.