511 research outputs found
Investigation of the SH3BP2 Gene Mutation in Cherubism
Cherubism is a rare developmental lesion of the jaw that is generally inherited as an autosomal dominant trait. Recent studies have revealed point mutations in the SH3BP2 gene in cherubism patients. In this study, we examined a 6-year-old Korean boy and his family. We found a Pro418Arg mutation in the SH3BP2 gene of the patient and his mother. A father and his 30-month-old younger brother had no mutations. Immunohistochemically, the multinucleated giant cells proved positive for CD68 and tartrate-resistant acid phosphatase (TRAP). Numerous spindle-shaped stromal cells expressed a ligand for receptor activator of nuclear factor kB (RANKL), but not in multinucleated giant cells. These results provide evidence that RANKL plays a critical role in the differentiation of osteoclast precursor cells to multinucleated giant cells in cherubism. Additionally, genetic analysis may be a useful method for differentiation of cherubism.</p
BIM-Based Construction Information Management Framework for Site Information Management
Projects in the construction industry are becoming increasingly large and complex, with construction technologies, methods, and the like developing rapidly. Various different types of information are generated by construction projects. Especially, a construction phase requires the input of many resources and generates a diverse set of information. While a variety of IT techniques are being deployed for information management during the construction phase, measures to create databases of such information and to link these various different types of information together are still insufficient. As such, this study aims to suggest a construction information database system based on BIM technology to enable the comprehensive management of site information generated during the construction phase. This study analyzed the information generated from construction sites and proposed a categorization system for structuring the generated information, along with a database model for storing such structured information. Through such efforts, it was confirmed that such a database system can be used for accumulating and using construction information; it is believed that, in the future, the continual accumulation and management of construction information will allow for corporate-level accumulation of knowledge as opposed to the individual accumulation of know-how
Disentangling The Effects Of The Employee Benefits On Employee Productivity
This study aimed to investigate the effects of employee benefits on employee productivity. There are conflicting views, positive and negative, with regard to the effect of employee benefits on employee productivity. Overall, we found that employee benefits have a positive impact on employee productivity through the embodied effect (direct effect). Specifically, according to a workplace panel survey in Korea conducted between 2005 and 2009, an increase of one unit in employee benefits leads to an increase of employee productivity by about 7.9%. In addition, we found that such effect is stronger in the manufacturing industry than in the non-manufacturing industry. Although there is no difference in the effect of benefits between large firms and small and medium-sized firms, the labor-embodied effect is stronger in large firms, and the capital-embodied effect is salient in small and medium-sized firms
Dynamical mean-field theory of Hubbard-Holstein model at half-filling: Zero temperature metal-insulator and insulator-insulator transitions
We study the Hubbard-Holstein model, which includes both the
electron-electron and electron-phonon interactions characterized by and
, respectively, employing the dynamical mean-field theory combined with
Wilson's numerical renormalization group technique. A zero temperature phase
diagram of metal-insulator and insulator-insulator transitions at half-filling
is mapped out which exhibits the interplay between and . As () is
increased, a metal to Mott-Hubbard insulator (bipolaron insulator) transition
occurs, and the two insulating states are distinct and can not be adiabatically
connected. The nature of and transitions between the three states are
discussed.Comment: 5 pages, 4 figures. Submitted to Physical Review Letter
Repair Using Conventional Implant for Ruptured Annulus Fibrosus after Lumbar Discectomy: Surgical Technique and Case Series
Study DesignA retrospective review of annulus fibrosus repair (AR) using a novel technique with a conventional implant.PurposeThe purpose of this study was to present the feasibility and clinico-radiological outcomes of a novel AR technique using a conventional implant to minimize recurrence following a lumbar discectomy (LD).Overview of LiteratureConventional repair techniques to prevent recurrence following LD have several drawbacks. The AR surgical technique has received little attention as an adjunct to LD.MethodsA total of 19 patients who underwent novel AR following LD, and who were available for follow-up for at least three years, were enrolled in this study. Several variables, including the type and size of disc herniation, and the degree of disc degeneration, were evaluated preoperatively. Postoperatively, the presence of clinical and radiological recurrence of disc herniation was evaluated from pain intensity and functional statuses, as well as an enhanced L-spine magnetic resonance imaging at the final follow-up. The presence of a peripheral hollow rim and inserted anchor mobilization were also evaluated during the follow-up.ResultsDuring follow-ups, there were no recurrences of disc herniation or complications, including neurovascular complications. Pain and functional disability improved significantly after surgery, and the improvement was maintained throughout the three-year follow-up period. No mobilization or implant peripheral hollow rim was observed during the follow-up.ConclusionsThis study examined the feasibility of a novel and easily available annulus implant technique following LD. These results suggest performing AR with this technique may be a valuable alternative for optimizing outcomes, if the procedure is performed in proper candidates
Suppression of magnetic ordering in XXZ-type antiferromagnetic monolayer NiPS3
How a certain ground state of complex physical systems emerges, especially in
two-dimensional materials, is a fundamental question in condensed-matter
physics. A particularly interesting case is systems belonging to the class of
XY Hamiltonian where the magnetic order parameter of conventional nature is
unstable in two-dimensional materials leading to a
Berezinskii-Kosterlitz-Thouless transition. Here, we report how the XXZ-type
antiferromagnetic order of a magnetic van der Waals material, NiPS3, behaves
upon reducing the thickness and ultimately becomes unstable in the monolayer
limit. Our experimental data are consistent with the findings based on
renormalization group theory that at low temperatures a two-dimensional XXZ
system behaves like a two-dimensional XY one, which cannot have a long-range
order at finite temperatures. This work provides experimental examination of
the XY magnetism in the atomically thin limit and opens new opportunities of
exploiting these fundamental theorems of magnetism using magnetic van der Waals
materials.Comment: 57 pages, 24 figures (including Supplementary Information
Parameter-robust linear quadratic Gaussian technique for multi-agent slung load transportation
This paper copes with parameter-robust controller design for transportation system by multiple unmanned aerial vehicles. The transportation is designed in the form of string connection. Minimal state-space realization of slung-load dynamics is obtained by Newtonian approach with spherical coordinates. Linear quadratic Gaussian / loop transfer recovery (LQG/LTR) is implemented to control the position and attitude of all the vehicles and payloads. The controller's robustness against variation of payload mass is improved using parameter-robust linear quadratic Gaussian (PRLQG) method. Numerical simulations are conducted with several transportation cases. The result verifies that LQG/LTR shows fast performance while PRLQG has its strong point in robustness against system variation
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