Association of gender with depression and anxiety in SSc^*.

<p>*Values are number/number of patients for whom the data is available (%), otherwise indicated in parenthesis.</p><p>SSc: systemic sclerosis; n: number; HADa: Hospital Anxiety and Depression scale for Anxiety; HADd: Hospital Anxiety and Depression scale for Depression.</p

Disability and health-related quality of life features associated with clinically significant symptoms of anxiety and depression in patients with systemic sclerosis.

<p>Values are given in median (interquartile range).</p><p>*After Bonferroni correction for multiple comparisons, a p-value less than 0.001 was considered statistically significant.</p><p>CHFS: Cochin Hand Function Scale; HAQ: Health Assessment Questionnaire; MACTAR: McMaster-Toronto Arthritis Patient Preference Disability Questionnaire; MCS: Mental Component Score; MHISS: Mouth Handicap In Systemic Sclerosis Scale; n: number; PCS: Physical Component Score; SF-36: Medical Outcomes Study 36-Item Short Form Health Survey.</p

Evolution of DLCO during the follow up.

<p>Panel A represents the individual data of the 75 patients and the red line is the trajectory of DLCO using the linear mixed model with random effect. DLCO significantly decreased over time (-1.5±0.3%/year (p<0.0001). Panel B is the progression-free survival of DLCO. Progression was defined as a decline of ≥15% of baseline DLCO.</p

Bivariate analysis of parameters associated with baseline value and slope of DLCO.

<p>Bivariate analysis of parameters associated with baseline value and slope of DLCO.</p