Reading/writing connection

Reading and writing have many common tasks. Children\u27s language abilities are nurtured through instructional practices that connect these commonalities. In a second-grade language arts program, tasks presented through reading instruction were related to children\u27s writing experiences. To support the reading-writing connection, a strong literature base was created. This base offered models of language and focuses for discussions to relate the commonalities of the processes. The teacher traced the transfer of reading instruction to the children\u27s writing through a collection of their writing pieces

Sandra Carpenter; Janis Hopkins to Mr. Meredith (10 October 1962)

https://egrove.olemiss.edu/mercorr_pro/2109/thumbnail.jp

SPR-5; MET-2 maternal reprogramming cooperates with the Dream Complex to regulate developmental cell fates

Histone methylation is a post-transcriptional modification to the N-terminal tails of histone core proteins that regulates DNA accessibility, and consequently, gene expression. Like DNA, histone methylation can be inherited between generations, and is highly regulated during embryonic development. At fertilization, histone methylation must undergo maternal reprogramming to reset the epigenetic landscape in the new zygote. During maternal reprogramming of histone methylation in the nematode, C. elegans, H3K4me (a modification associated with active transcription) is removed by the H3K4 demethylase, SPR-5, and H3K9me (a modification associated with transcriptional repression) is subsequently added by the histone methyltransferase, MET-2. Recently, it was demonstrated that SPR-5; MET-2 maternal reprogramming antagonizes the H3K36 methyltransferase, MES-4, which maintains a transcriptional memory of a subset of germline genes between generations. Maternal loss of SPR-5 and MET-2 results in ectopic expression of MES-4 germline genes in somatic tissues and a severe developmental delay. Recently, exciting new literature suggest that the DREAM Complex, a transcriptional repressor complex that regulates cell cycle, also represses MES-4 germline genes in somatic tissues suggesting that the DREAM Complex and SPR-5; MET-2 maternal reprogramming may work together to prevent ectopic germline gene expression in somatic tissues and developmental delay. To test this hypothesis, we knocked down Dream Complex members LIN-35 and LIN-9 in spr-5; met-2 mutants using RNA interference (RNAi). We found that loss of either LIN-35 or LIN-9 exacerbates the severe developmental delay that we normally observe in spr-5; met-2 mutants leading to a complete larval arrest. These findings suggest that the Dream Complex and SPR-5; MET-2 maternal reprogramming work together to ensure proper development and provide insight into how an evolutionary conserved transcriptional repressor complex cooperates with maternal reprogramming of histone methylation to regulate germline versus somatic cell fates

Social media and data privacy in education: An international comparative study of perceptions among pre-service teachers

Social media platforms offer many educational possibilities, but they also create challenges associated with their business models. One increasingly relevant challenge, especially in the context of teacher education and schools, is personal data privacy. When considering social media and data privacy in education, taking into account culture-specific aspects in different countries, such as legal frameworks, user attitudes, and cultural values, is uncommon. This cross-sectional study explores the perceptions of pre-service teachers (N = 225) from universities in four countries (Germany, New Zealand, Spain, and the USA) concerning educational and professional social media use, as well as data privacy awareness and practices. Data were collected via a survey and analyzed through descriptive and inferential statistics. Results indicate that along with common belief in social media's educational potential, data privacy concerns were present, knowledge related to data privacy was lacking, and differences existed between participants from the different universities. We discuss these results in relation to legal frameworks, user attitudes, and cultural values concerning social media data privacy, and consider implications for research, practice, and policy

An all-inclusive and transparent view of a vascular program's direct impact on its health system

ObjectiveThis study explores the fiduciary advantage of a Vascular Surgery program to an academic, tertiary care hospital.MethodsThis is a retrospective review of hospital (HealthQuest) and physician (IDX) billing databases from April 2009 to September 2010. We identified all patients interacting with Vascular Surgery (VS) to provide an overview of global finances. Patients introduced solely by VS were identified to minimize confounding of the downstream effect. Outcome measures obtained were revenue, average and total gross margin, relative value unit production, and service utilization.ResultsA total of 552 cases were identified demonstrating $13 million in revenue. This translated into a gross margin of$5 million. Examined per surgeon, VS was the most profitable, producing $1.6 million. Lower extremity amputation had the highest average gross margin at$34,000. Notably, $8 million in direct cost is among the highest in the health system. A total of 137 cases unique to VS generated$5 million in total revenue. This patient subset made use of up to 29 physician specialty services. General Medicine and Radiology were the most frequently utilized.ConclusionThe overall profitability of a comprehensive vascular program is tremendously positive. This study verifies that new vascular-specific referrals are a significant catalyst for revenue

Homeotic genes controlling flower development in Antirrhinum

In order to study genes controlling flower development, we have carried out an extensive transposon-mutagenesis experiment in Antirrhinum majus. More than 15 independent homeotic mutations were obtained, allowing three categories of genes to be defined. The first includes floricaula (flo), a primary gene required for the initiation of the floral developmental pathway. In the absence of the wild-type flo product, proliferating inflorescence meristems arise in place of flowers. The flo gene has been isolated and shown to be expressed transiently in a subset of organ primordia in the floral meristem. The second category includes genes that affect the identity, and also sometimes the number, of whorls of organs in the flower. These genes act in overlapping domains so that each whorl has a distinct combination of gene functions, suggesting a model for the genetic control of whorl identity and number. Genes of the third category control differences between organs in the same whorl and hence the overall symmetry of the flower. We discuss how the basic plan of the flower and inflorescence may arise through the interactions between the three categories of genes